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Pain clinical trials

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NCT ID: NCT05471219 Completed - Pain Clinical Trials

The Effect of Focus on Vaginal Examination Experience and Pain Level: a Randomized Controlled Trial

Start date: May 18, 2021
Phase: N/A
Study type: Interventional

Vaginal examination contains many negative emotions such as pain, fear, stress, and discomfort for women. When the literature was examined, no study was found in which the focus method was used to reduce or eliminate the feelings that cause negative emotions in women in the vaginal examination experience. For this reason, our research will be a first in the literature and it is thought that it will contribute to the field. In this context, it is assumed that the focusing behavior based on the door control theory will reduce the pain level of primiparous women who will have a vaginal examination for the first time in labor, positively affect the vaginal examination experience and experience a positive birth. In the research; Ho hypothesis: Focus has no effect on the vaginal examination experience of pregnant women. Hypothesis H1: Focus has an impact on the vaginal examination experience of pregnant women. Ho hypothesis: Focus has no effect on vaginal examination pain level of pregnant women. Hypothesis H1: Focus has an effect on the vaginal examination pain level of pregnant women. It was aimed to examine the effect of focusing on the first vaginal examination experience and pain level of primiparous women in labor by establishing hypotheses.

NCT ID: NCT05470075 Recruiting - Pain Clinical Trials

A Study to Evaluate the Efficacy and Safety of HR18042 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.

Start date: August 11, 2022
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, double-blind, dose finding, parallel controlled with active drug and placebo, phase II clinical trial, and the purpose of the study is to evaluate the efficacy and safety of HR18042 tablets for postoperative analgesia after impacted teeth removal surgery.

NCT ID: NCT05470049 Not yet recruiting - Pain Clinical Trials

A Clinical Study of the Combination of SHR8554 Injection and SHR0410 Injection for the Treatment of Pain After Abdominal Surgery.

Start date: August 1, 2022
Phase: Phase 2
Study type: Interventional

The primary objective is to evaluate the analgesic efficacy of the combination of SHR8554 injection and SHR0410 injection compared with SHR8554 injection in patients with acute postoperative pain following abdominal surgery

NCT ID: NCT05469451 Not yet recruiting - Pain Clinical Trials

Effect of the Diode Laser (940nm) on Orthodontics

Start date: August 20, 2022
Phase: N/A
Study type: Interventional

To evaluate the effect of the low power density 940nm diode laser in the total relief of dental crowding during the alignment phase and the perception of pain in patients who initiate orthodontic treatment.

NCT ID: NCT05468398 Recruiting - Pain Clinical Trials

Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA

Start date: December 2, 2020
Phase: N/A
Study type: Interventional

The study team aims to investigate whether implementing virtual reality therapy (VRT) during Genicular nerve radiofrequency ablation (GNRFA) procedure will provide better alleviation of procedural pain and augmented satisfaction for patients.

NCT ID: NCT05466656 Active, not recruiting - Pain Clinical Trials

Sumamos Excelencia 2022

Start date: November 25, 2021
Phase: N/A
Study type: Interventional

There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices. Quasi-experimental, multicentre, before and after. Primary care, hospital units and nursing homes, and the patients attended at both. Implementation of evidence-based recommendations by application of a continuous quality improvement cycle model (process of improvement by reference to a prior baseline clinical audit. Data will be collected at baseline and, during the first year of follow up, at months (3, 6, 12)

NCT ID: NCT05466604 Completed - Pain Clinical Trials

Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema

Start date: December 1, 2019
Phase: Phase 4
Study type: Interventional

The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection. For this purpose, 60 participants with symmetrical mandibular wisdom teeth enrolled the present study. All measurements and evaluations were performed before and 1, 2, 3, and 7 days later the operation.

NCT ID: NCT05462964 Completed - Pain Clinical Trials

Reducing Pain During Orogastric Tube Insertion in Newborns: Use of Pacifiers and Pacifiers Sweetened With 25% Dextrose

Start date: December 25, 2018
Phase: N/A
Study type: Interventional

Orogastric tube(OGT) placement, which is used for monitoring, diagnostic and therapeutic purposes, causes pain and stress in premature and term newborns. Non-pharmacological pain intervention with pacifiers and sweetener solutions (sucrose, dextrose, etc.) in newborns is a viable nursing approach to reduce pain. In the limited number of studies in the literature, it was seen that pacifiers and sucrose were used in nasogastric tube(NGT) applications and they were especially focused on premature babies. In our study, due to the fact that it was conducted in term newborns and, unlike the limited number of studies, OGT was placed in the stomach in the form of a pacifier and a 25% dextrose pacifier leaking from the rim. Our study was conducted as a randomized controlled experimental study to examine the effect of using pacifiers and dextrose pacifiers on pain reduction during orogastric tube placement, and also to evaluate the effects on behavioral response and physiological parameters (heart rate, oxygen saturation) in newborns.In addition, it was thought that the fact that the study was carried out by passing a pacifier and a pacifier sweetened with 25% dextrose, would facilitate progress and reduce trauma by stimulating the swallowing reflex in newborns via a pacifier as in adults.The population of the study consisted of term newborns at 38-42 weeks of gestation who were hospitalized in the Neonatal Intensive Care Unit of a hospital in Turkey between April-December 2019. The sample group randomly consisted of 60 newborns (Control group: 20, Intervention group with only pacifiers:20, with dextrose flavored pacifiers:20). 20 babies in the intervention group were given only pacifiers and 20 babies were given a pacifiers flavored with dextrose 2 minutes before the OGT insertion. The procedure was performed by leaking the tube from the edge of the pacifiers. Routine OGT insertion was performed in the control group. The data collection process was recorded with a camera. The Neonatal Infant Pain Scale (NIPS), the highest heart rate and lowest oxygen saturation from physiological pain responses, and crying time from behavioral parameters were evaluated by the researcher by watching the camera recording. Variance analysis, Shapiro Wilk, Kruskal Wallis, Chi-square, Bonferro, and Wilcoxon tests were used in the statistical analysis of the study. The SPSS v22 package program was used for statistical analysis and the significance level was taken at α=0.05.

NCT ID: NCT05459246 Completed - Pain Clinical Trials

The Effect of Virtual Reality Application on Pain Severity, Anxiety Level and Patient Satisfaction

Start date: July 4, 2022
Phase: N/A
Study type: Interventional

In this study; It is aimed to examine the Effect of Virtual Reality Based Relaxation Program on Pain Severity, Anxiety Level and Patient Satisfaction in Patients Who Will Be Applied Angiography.

NCT ID: NCT05459207 Recruiting - Pain Clinical Trials

Association Between Body Composition and Pain in Spinal Cord Injury

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and explore the influence of body composition on these responses, in individuals with chronic spinal cord injury