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Pain clinical trials

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NCT ID: NCT00576173 Completed - Pain Clinical Trials

An Open Label Study to Evaluate Safety, Tolerability and Clinical Utility of ULTRACET® (37.5mg Tramadol Hydrochloride/325mg Acetaminophen) for the Treatment of Breakthrough Pain in Cancer Patients

Start date: December 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the analgesic effectiveness and safety of 37.5mg Tramadol hydrochloride/325mg Acetaminophen in the treatment of breakthrough pain in cancer patients.

NCT ID: NCT00576043 Completed - Pain Clinical Trials

Effect of Virtual Endoscopy Simulator Training on Real Patient Endoscopy

endosim
Start date: March 2004
Phase: N/A
Study type: Interventional

Trainees (Residents in internal medicine), naive to real patient endoscopy, will be randomized to receive either 3 weeks/2 hours per day of structured training for a total of 20 hours on the virtual endoscopy simulator GI-Mentor or no training before starting on-patient endoscopy in the University of Vienna Medical School Endoscopy Unit. Patients satisfaction and pain, technical accuracy and number of found/missed pathologies as well as average time for successful endoscopy will be recorded. After one month or 50 supervised, self performed endoscopies, trainees will be evaluated again with the above mentioned criteria during ten consecutive investigations.

NCT ID: NCT00576017 Completed - Pain Clinical Trials

A Study to Evaluate the Safety and Effectiveness of Fentanyl-TTS Compared to Weak Opioids in Patients With Moderate to Severe Chronic Cancer Pain Previously Treated With NSAIDS (Non-steroidal Anti-inflammatory Drugs).

Start date: October 2003
Phase: Phase 4
Study type: Interventional

To show, using the analgesic WHO scale, that fentanyl-TTS may be directly used for treating moderate to severe cancer pain in patients treated with NSAIDs, acetaminophen, or metamizole (first step drugs) avoiding the second step, and may be at least as effective and safe as currently used second step drugs, minor opioids.

NCT ID: NCT00573963 Completed - Pain Clinical Trials

Efficacy of the Transversus Abdominus Plane (TAP) Block for Post-Cesarean Delivery Analgesia

Start date: December 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if patients having the transversus abdominal place (TAP) block at the end of a cesarean delivery have less pain in the post-delivery period than those who do not. Freezing medication is injected between the layers of muscle on either side of the belly, to freeze the nerves that carry pain stimuli from an abdominal wound. This technique has been useful for many abdominal operations, and has recently been studied in cesarean sections, however more information is needed.

NCT ID: NCT00571636 Completed - Pain Clinical Trials

Continuous Infusion of Fentanyl in Preterm on MV

Start date: December 2007
Phase: Phase 3
Study type: Interventional

The objective of this randomized, double-blind trial is to compare the efficacy and safety of 2 therapeutic regimens of fentanyl administration in a population of preterm newborns of GA <= 32 weeks in MV: - Group A) continuous infusion of Fentanyl + open label boluses of Fentanyl; - Group B) continuous infusion of placebo + open label boluses of Fentanyl.

NCT ID: NCT00564486 Completed - Pain Clinical Trials

Analgesic Efficacy & Safety of Intravenous (IV) Acetaminophen Versus Placebo for the Treatment of Postop Pain

Start date: November 2007
Phase: Phase 3
Study type: Interventional

This research study will look at the pain relieving ability and safety of using repeated doses of intravenous (into the vein [IV]) acetaminophen in the treatment of moderate postoperative pain after planned or elective abdominal laparoscopic surgery, such as a laparoscopic abdominal hysterectomy or laparoscopic cholecystectomy (removal of the gall bladder).

NCT ID: NCT00562211 Completed - Pain Clinical Trials

Efficacy of a New Topical Anesthetic

Start date: November 2007
Phase: Phase 1/Phase 2
Study type: Interventional

A new topical anesthetic which contains 5% lidocaine and a disinfection ingredient has been developed and is tested in this study (LidoDyn). The study examines the efficacy of LidoDyn by comparing it with an already proven anesthetic agent (EMLA crème).

NCT ID: NCT00560443 Completed - Pain Clinical Trials

RCT on Ketorolac and Tramadol in Bone Fractures Pain of Child

Start date: February 2008
Phase: Phase 4
Study type: Interventional

Randomized double blind Trial with the aim to estimate effectiveness of two therapeutic regimes per os on pain due to not compound bone fractures in child 4-17 years old: - ketorolac 0,5 mg/kg (1 drop every 2 Kg) - tramadol 2,5 mg/Kh (1 drop every 2 Kg) Intensity of pain will be estimated with linear 1 to 10 or analogic McGrath type scale every 20 min. The main objectives are the evaluation of pain decreasing in every group, the time of decreasing, the intensity of pain during procedures (ex. Xray) and the occurrence of side effects Secondary outcomes are comparison between the two groups on effectiveness on pain and on side effects

NCT ID: NCT00560196 Completed - Depression Clinical Trials

Pain Processing in Anxiety and Depression

Start date: November 2007
Phase: N/A
Study type: Observational

The purpose of the study is to investigate pain, anxiety and depression in patients with panic anxiety disorders without pain or depression without pain compared with healthy volunteers

NCT ID: NCT00553982 Completed - Pain Clinical Trials

Patellar Resurfacing in Total Knee Arthroplasty

Start date: October 2007
Phase: N/A
Study type: Interventional

Background: The best treatment of the patella during total knee arthroplasty (TKA) is controversial. The implantation of a patellar component adds to the operation time and the costs of the operation.There is a huge variation as to whether the patella is resurfaced or not during TKA. Meta-analysis of prospective, randomised trials might indicate that patellar resurfacing reduces the risk of reoperation and anterior knee pain, but drawing firm conclusions is not possible and additional, high quality randomised trials are required. Purpose: The aim of this study is to determine whether ther is a difference between the two groups in knee pain, functions, patient satisfaction and quality of life after TKA.