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Pain, Postoperative clinical trials

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NCT ID: NCT05549011 Completed - Hip Fractures Clinical Trials

PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia

Start date: September 20, 2022
Phase:
Study type: Observational

This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal anesthesia in patients who are scheduled for surgery due to hip fracture.

NCT ID: NCT05548660 Active, not recruiting - Acute Pain Clinical Trials

Pharmacogenetic-guided Choice of Post-surgery Analgesics

PRECISE
Start date: October 13, 2022
Phase: N/A
Study type: Interventional

Pharmacogenomics (PGx) is the study of how genes affect a person's response to drugs. PGx testing for certain genes can help predict the risk of side effects or therapeutic failure from analgesics. Testing is not regularly performed in clinical practice due to long wait times for results and challenges with integrating test results in the electronic health record. Investigators leading this study hope to find out if providing surgeons with the ability to order a PGx test and electronically receive results with dosing recommendations will increase the use of these tests to guide analgesic choice and improve patient outcomes. This is a prospective, two-arm randomized implementation study. Eligible participants will be randomly assigned to receive genotype-guided analgesic selection (intervention arm) or usual care (control arm). Both cohorts will undergo pharmacogenetic testing at the time of consenting. The investigators will primarily measure the feasibility of using this test to guide analgesic selection.

NCT ID: NCT05548582 Active, not recruiting - Pain Clinical Trials

Reduced Opioid Prescription After Laparoscopic Hysterectomy

Start date: January 12, 2023
Phase: N/A
Study type: Interventional

Given the nationwide epidemic of opioid use and abuse (in part due to over prescription), this study aims at addressing the need for opioid prescription after laparoscopic hysterectomy.

NCT ID: NCT05547932 Completed - Breast Cancer Clinical Trials

The Effect of Rhomboid Intercostal Block and Serratus Anterior Plane Block on Postoperative Respiratory Functions

RIBSAB
Start date: September 21, 2022
Phase: N/A
Study type: Interventional

Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. Serratus anterior plane block is used to block lateral cutaneous branches of intercostal nerves between T2 and T6, in addition, it is also known to block thoracodorsal nerve and long thoracic nerve. Both of the blocks are usually performed for postoperative analgesia following breast surgery. The primary hypothesis of the study is that FEV1 value of the patients who will receive modified radical mastectomy (MRM) and rhomboid intercostal plane (RIP) block combined with serratus anterior plane (SAP) will be higher than FEV1 value of the patients in the no-block group. The secondary hypothesis is that RIP+SAP blocks will provide reduction in the pain scores and opioid consumption in the postoperative first 24 hours.

NCT ID: NCT05543785 Recruiting - Clinical trials for Postoperative Pain, Acute

Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries

K-IVRAg
Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries. From the previous documented effectiveness and safety of intravenous (IV) administration of ketorolac in the circulatory-isolated limb as a part of intravenous regional anesthesia; we hypothesized that in orthopedic surgeries done with tourniquet, intravenous (IV) administration of ketorolac after tourniquet inflation, will act as intravenous regional analgesia. So, it will prolong the postoperative analgesic duration as a primary outcome.

NCT ID: NCT05543668 Completed - Pain, Postoperative Clinical Trials

Association of Preoperative Pain With Moderate to Severe Acute Pain After Laparoscopic Cholecystectomy.

Start date: September 16, 2022
Phase:
Study type: Observational

Despite advancement in perioperative pain management, more than half of the patients still report moderate-severe pain after surgery. Among several risk factors, pre-existing pain has consistently been shown to predict postoperative severe pain.If one can predict the patients who will experience more post-operative pain, then a more aggressive pain management strategy can be adopted perioperatively. This would improve patient satisfaction and prevent poor outcomes such as chronic pain after surgery. Therefore, our primary aim is to find out whether presence of pre-existing preoperative pain would predict moderate-severe acute pain after laparoscopic cholecystectomy. Moreover, we plan to use Patient Reported Outcomes Measurement Information System (PROMIS) scale to assess preoperative pain intensity and pain-related behaviors. Primary &Secondary Objectives: Primary objectives To investigate the association between preexisting preoperative pain (more than 3 months duration) and postoperative moderate-severe acute pain after laparoscopic cholecystectomy. Secondary objectives .1. To investigate the association between preoperative PROMIS(patient reported outcome measurement and information system) domain (PROMIS pain intensity score, PROMIS pain interference score, PROMIS pain behavioural score) and postoperative moderate-severe acute pain after LC. 2. To examine baseline demographic, clinical, psycho-behavioural features and intraoperative factors in relation to dynamic moderate to severe pain after LC. 3. To identify perioperative predictors for acute postsurgical pain. 4. To find out the incidence of shoulder tip pain after LC.

NCT ID: NCT05543109 Enrolling by invitation - Pain, Postoperative Clinical Trials

Ultrasound Guided Psoas Compartment Block vs Suprainguinal Fascia Iliaca Compartment Block

Start date: September 29, 2022
Phase: N/A
Study type: Interventional

The aim of this study was to compare the intraoperative and the postoperative analgesic effect of psoas compartment block (PCB) and supra-inguinal fascia iliaca compartment block (SFIB) in pediatric patients undergoing developmental dysplasia of the hip

NCT ID: NCT05541666 Recruiting - Clinical trials for Total Knee Replacement

The Effect of Emotional Freedom Technique on Postoperative Pain and Anxiety on Total Knee Replacement

Start date: March 7, 2022
Phase:
Study type: Observational

Since pain is a complex and unpleasant feeling that affects the individual physically, mentally and socially, it should be controlled. It is also known that major surgeries such as orthopedics and traumatology, general surgery and cardiovascular surgery cause fear of death in the patient, and this fear is then replaced by general anxiety and post-operative pain. The emotional freedom technique is a method that uses cognitive functions and physical components (tapping acupuncture points) to bring about psychological changes. It is also defined as "needle-free acupuncture" or "an emotional form of acupressure" because it is a gentle, non-invasive procedure and uses acupuncture meridians. This method, which is very old in Eastern cultures, started to be used in the West in the 1980s. In this developed technique, all 12 points on the 12 basic meridians, which are the flow paths of the energy in the body, are used. In the emotional liberation technique tour, general anxiety, phobias, post-traumatic stress disorder, fears and the discomfort caused by anxiety are eliminated and all kinds of targeted problems are cured. Considering the patients as a whole in terms of biopsychosocial is the basic element of nursing. It is inevitable to experience pain and anxiety in the post-operative period in individuals who are in a foreign environment such as a hospital and who have undergone major surgery such as total knee replacement. With this study, it is expected that the emotional freedom technique will contribute to the national and international literature on the effect of pain and anxiety in the post-operative period and will be a source of information in the development of nursing science on the use of non-pharmacological treatments that can be used in the treatment of pain and anxiety in patients.

NCT ID: NCT05540691 Completed - Postoperative Pain Clinical Trials

Effect of Noise Blocking During General Anesthesia on Postoperative Pain

Start date: October 8, 2022
Phase: N/A
Study type: Interventional

To investigate the effect of noise blocking during general anesthesia on postoperative pain in patients undergoing laparoscopic abdominal surgery. The aim of this study was to determine whether noise blocking can reduce postoperative pain, analgesic use, and its possible effects on intraoperative electrocorticogram.

NCT ID: NCT05536362 Completed - Colon Cancer Clinical Trials

Propofol With Clonidine and Ketamine Throughout Colon Cancer Surgery

Start date: February 1, 2021
Phase: Phase 1
Study type: Interventional

The Study Showed that combining clonidine and ketamine together can increase the likelihood of achieving a sufficient level of anaesthesia while minimizing post-operative discomfort and inflammation.