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Pain, Postoperative clinical trials

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NCT ID: NCT04291833 Completed - Knee Osteoarthritis Clinical Trials

Prospective, Assessment of Vitamin D and Calcium Supplementation, Improvement of Nutritional Status and Preoperative Rehabilitation in Patients Before Knee Arthroplasty.

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

Prospective randomized study of 150 patients qualified for knee arthroplasty between 2015 and 2017. Patients were randomized into 3 groups receiving vitamin D and calcium supplementation, increased protein supply and preoperative rehabilitation, respectively. Following factors were analyzed: changes in vitamin D3, calcium, total protein, albumin and CRP levels during preparation for surgery, nutritional status on the Subjective Global Assessment (SGA) scale, osteoporosis risk assessment according to the Osteoporosis Risk SCORE, level of pain felt on the scale VAS and the number of analgesics used, the result of the Duke Activity Status Index, the result of the following scales: Cardiac Risk Index for Orthopedic Surgery (Lee), Knee injury and Osteoarthritis Outcome Score (KOOS), Fear Avoidance Beliefs Questionnaire (FABQ) about Physical Activity, The Quality of Life Scale (QOLS). Additionally, the occurrence of perioperative complications was analyzed (e.g. venous thrombosis and pulmonary embolism, wound or joint infection, excessive bleeding, loosening of the implant, bone fracture or fracture, pain).

NCT ID: NCT04286035 Completed - Pain, Postoperative Clinical Trials

Two Different Blocks for Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty

Start date: April 2, 2019
Phase: Phase 4
Study type: Interventional

The frequency of femoral nerve block and adductor canal block for analgesia after TKA(total knee arthroplasty) increases with the use of ultrasonography in regional anesthesia. In this study, we aimed to compare the effects of femoral nerve block and adductor canal block on postoperative analgesia in patients undergoing unilateral knee arthroplasty.

NCT ID: NCT04284930 Completed - Pain, Postoperative Clinical Trials

Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management

Start date: February 2016
Phase: Phase 4
Study type: Interventional

Effective post surgical pain control in patients undergoing unilateral deep inferior epigastric perforator (DIEP) free flap reconstruction.

NCT ID: NCT04280432 Completed - Clinical trials for Cesarean Section Complications

Monocentric Observational Study: Postoperative Pain After Cesarean Section: Incidence and Risk Factors.

Start date: March 1, 2017
Phase:
Study type: Observational

The purpose of this prospective study was to assess chronic pain 3, and 12 months after cesarean delivery in a cohort of women in University hospital La Paz. We also aim to study the possible contribution of anesthetic and surgical risk factors for the development of Chronic post-surgical pain after cesarean (PCSCP)

NCT ID: NCT04278846 Completed - Pain, Postoperative Clinical Trials

Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Patient Undergoing Breast Reconstruction With Tissue Expander

Start date: August 22, 2014
Phase: Phase 4
Study type: Interventional

Patients undergoing breast reconstruction with tissue expanders will be treated with a local anesthetic during their procedure and monitor their post-operative pain level and amount of oral pain medication taken. This information will be used to determine if liposomal bupivacaine provides better and longer pain control vs. bupivacaine HCl.

NCT ID: NCT04277975 Completed - Postoperative Pain Clinical Trials

Liberal vs. Restricted Post-discharge Opioid Prescribing Following Midurethral Sling

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The specific objective of this proposal is to evaluate pain and opioid use following a midurethral sling (MUS) under two different opioid prescribing schemes. The central hypothesis is that, in spite of the fact that opioids are often routinely prescribed by many surgeons following this procedure, most patients do not require them for pain control, and patients who are not prescribed postoperative will have similar pain scores and pain control satisfaction compared with patients who are routinely prescribed a standard amount of opioids for postoperative pain control.

NCT ID: NCT04277611 Completed - Pain, Postoperative Clinical Trials

Comaprison Between QLB and ESPB in Patients for PCNL Operation

Start date: April 20, 2021
Phase: N/A
Study type: Interventional

comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.

NCT ID: NCT04277520 Completed - Root Canal Therapy Clinical Trials

Postoperative Pain Assessment After Using Different Kinematics

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate postoperative pain after endodontic instrumentation using rotation, reciprocation and adaptive motion.

NCT ID: NCT04265456 Completed - Postoperative Pain Clinical Trials

A Phase 1 Study to Evaluate Pregabalin and Acetaminophen in Healthy Volunteers

Start date: January 14, 2020
Phase: Phase 1
Study type: Interventional

This is a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose study to determine a maximum tolerated dose of IV PGB and to evaluate the safety, tolerability, and PK of an admixture of IV PGB and a fixed dose of 1300 mg IV APAP in healthy adult volunteers.

NCT ID: NCT04262245 Completed - Postoperative Pain Clinical Trials

Comparison of Different Irrigation Activation Techniques on Postoperative Pain After Endodontic Treatment

Start date: January 5, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of different irrigation activation methods on postoperative pain using visual analog scale (VAS) using Xp-endo Finisher, EndoActivator and Passive ultrasonic irrigation activation techniques with traditional irrigation method. In this study, Traditional Irrigation (GI), Xp-endo Finisher (XPF), Passive Ultrasonic Irrigation (PUI), EndoActivator (EA) techniques will be used for irrigation activation. Twenty-five maxillary or mandibular single root and canal-shaped nonvital teeth will used in each group. Root canals will be prepared with TF-Adaptive system. Four different activation techniques will be applied during final irrigation. The canal treatments will be completed in one stage and postoperative pain analysis will be taken with VAS (Visual Analog Scale) scale after 12-24-48 hours. Statistical analysis will be performed with Mann Whitney-U test.