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Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

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NCT ID: NCT06359171 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Effectiveness of the ARTH-e Application on Adherence to Physical Exercises in Patients Suffering From KOA: RCT

ARTH-e3
Start date: May 3, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of a smartphone-based e-health application (intervention group) compared with standard care (control group) in terms of changes in adherence in patients with knee osteoarthritis using the EARS questionnaire. In addition, other questionnaires presented in the appendix (KOOS, TSK, EPAP, EQ-5D-3L, pain) will be given to all patients in order to meet the secondary evaluation criteria.

NCT ID: NCT06358521 Recruiting - Knee Osteoarthritis Clinical Trials

Determining the Impact of a Physiotherapist-led Primary Care Model for Hip and Knee Pain - A Cluster Trial

Start date: October 2, 2023
Phase: N/A
Study type: Interventional

This is a cluster randomized controlled trial to to evaluate the individual and health system impacts of implementing a new physiotherapist-led primary care model for hip and knee pain in Canada.

NCT ID: NCT06357741 Completed - Knee Osteoarthritis Clinical Trials

Clinical Study of Desuzumab in the Treatment of Knee Osteoarthritis

CSODITTOKO
Start date: March 2, 2023
Phase:
Study type: Observational

As an activator of inhibiting nuclear factor kB receptor, denosumab affects osteoclast differentiation and development by inhibiting OPG/RANKL-RANK bone regulatory axis pathway. Therefore, denosumab is widely used in the treatment of bone diseases such as osteoporosis. Osteoporosis is closely related to knee osteoarthritis. RANKL-RANK pathway also plays a key role in the pathogenesis of knee osteoarthritis. Therefore, the investigators propose the hypothesis that denosumab can effectively treat knee osteoarthritis.

NCT ID: NCT06347692 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Effect of Antigravity Treadmill in Knee Osteoarthritis (AGTreadmill)

AGTreadmill
Start date: April 7, 2024
Phase: N/A
Study type: Interventional

To date, the anti-gravity treadmill, as a representative method of lower body positive pressure treadmills, has been rarely reported for knee osteoarthritis rehabilitation. Purpose: This study aims to evaluate the effect of antigravity treadmill training on pain, gait characteristics, and function in patients with knee osteoarthritis.

NCT ID: NCT06343909 Recruiting - Knee Osteoarthritis Clinical Trials

Foot and Hip Abductor Strengthening in Patients With Knee Osteoarthritis.

Start date: November 23, 2023
Phase: N/A
Study type: Interventional

The study will be Randomized controlled trail, Subject diagnosed with knee osteoarthritis meeting predetermined inclusion and exclusion criteria will be divided into two groups. Pre assessment will be done using pain, ROM, function, foot arches and knee alignment as subjective measurement through KOOS questionnaire, goniometer, 2D frontal plane projection, Berkemann foot prints using ink and paper ,30s chair stand test, nine step stair climb,40m fast paced walk test,Global rating of change score respectively . One group will be treated with hip abductor strengthening exercise along with conventional exercises and second group will be treated with intrinsic foot muscle strengthening exercise along with conventional exercises. Post treatment values recorded after the session.After data collection from defined study setting,data will be entered and analyzed at Riphah International University,Lahore

NCT ID: NCT06339944 Recruiting - Knee Osteoarthritis Clinical Trials

Effects of Sensory Motor Training and Kinesthetic Exercises in Knee Osteoarthritis.

Start date: November 23, 2023
Phase: N/A
Study type: Interventional

In this study i will see the effects of kinesthetic exercises and sensory motor training on pain and range of motion in patients with knee OA.

NCT ID: NCT06336278 Completed - Knee Osteoarthritis Clinical Trials

Relationship Between Central Sensitization and Kinesiophobia in Knee Osteoarthritis

Start date: October 1, 2022
Phase:
Study type: Observational [Patient Registry]

Objective: The knee joint is one of most common locations in OA. In recent years, it has been accepted that there are different pain phenotypes and patient subgroups in knee OA and that central sensitization (CS) mechanisms are at the forefront in some patients. It is also known that fear of movement, known as kinesiophobia, develops in patients with chronic pain. The aim of this study is to investigate CS and kinesiophobia in patients with knee OA, their relationships with each other, and their effects on pain intensity, functional status, pain catastrophizing and depression. Materials and Methods: Forty-two patients with knee OA and 42 healthy subjects participated in our study. Demographic data, body mass index, habits, comorbidities, medications of participants and disease duration and radiographic grade of knee OA patients were recorded. VAS was used to assess the severity of pain and WOMAC was used to assess pain and functional status in patients with OA. Algometer (pressure pain threshold measurement) and Central Sensitization Inventory were used to evaluate central sensitization in all participants. Pressure pain threshold (PPT) was measured at 3 different points: knee joint, cruris and forearm. The presence of kinesiophobia was assessed with the Tampa Scale af Kinesiophobia (TSK). Pain Catastrophizing Scale (PCS) and Beck Depression Inventory (BDI) were used to assess chronic pain related symptoms.

NCT ID: NCT06336200 Recruiting - Knee Osteoarthritis Clinical Trials

Knee Osteoarthritis and Kinesiophobia

Start date: January 1, 2024
Phase:
Study type: Observational

Kinesiophobia after total knee arthroplasty is an important parameter affecting recovery. However, the relationship between kinesiophobia and the factors it may cause is not clear. Therefore, this study aimed to examine the relationship between kinesiophobia, pain, fear of falling, mobility and proprioception in the early period after total knee arthroplasty.

NCT ID: NCT06331858 Recruiting - Pain Clinical Trials

The Effect of Adding Instrumented Hip Concentric Abductor Strengthening Exercise in Knee Osteoarthritis

Start date: September 20, 2023
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effectiveness of adding hip device-assisted concentric abductor strengthening (HDACAS) program to knee device-assisted concentric flexor-extensor strengthening (KDACFES) program on pain, function, physical performance, quality of life and gait parameters in patients with knee osteoarthritis (OA).

NCT ID: NCT06329492 Enrolling by invitation - Osteoarthritis Clinical Trials

Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis

A2MRP
Start date: January 9, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness and safety of autologous alpha-2 macroglobulin rich plasma (A2MRP) injections in the treatment of knee osteoarthritis (OA).