Clinical Trials Logo

Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

Filter by:

NCT ID: NCT02876120 Not yet recruiting - Knee Osteoarthritis Clinical Trials

The STavanger osteoARThritis Study

START
Start date: September 2016
Phase: N/A
Study type: Interventional

The START study will implement osteoarthritis (OA) treatment recommendations to increase the use of recommended treatment modalities and reduce non-desired events (e.g. unnecessary referrals to secondary care, unnecessary use of costly imaging modalities and use of treatment modalities supported by low quality of evidence). The purpose of the STavanger osteoARThritis (START) study is to improve the quality of OA care and increase the collaboration between health care professionals in primary health care and across health care levels.

NCT ID: NCT02873611 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Estimation of the Localization Accuracy of the Genicular Ablation Procedure Applied for Chronic Pain Suppression

Start date: August 2016
Phase: N/A
Study type: Interventional

Estimation of the localization accuracy of the genicular ablation procedure applied for chronic pain suppression

NCT ID: NCT02865161 Completed - Knee Osteoarthritis Clinical Trials

Amtolmetin Gaucil in Knee Osteoarthritis

AGATA
Start date: February 2015
Phase: Phase 4
Study type: Observational

This study is conducted to study the efficacy and safety of Niselat in patients with osteoarthritis.

NCT ID: NCT02863120 Recruiting - Knee Osteoarthritis Clinical Trials

Liposomal Bupivacaine vs Adductor Canal Block in Total Knee Arthroplasty

Start date: July 2016
Phase: Phase 4
Study type: Interventional

This study is being done to evaluate the outcomes of patients undergoing total knee replacement with two different methods of local pain control:shots of liposomal bupivacaine, a long acting anesthetic, directly into the knee during surgery or anesthetic delivered continuously to the adductor canal to provide long term pain relief. The goal is to try to find a standard protocol that provides the greatest pain relief for patients undergoing total knee replacement.

NCT ID: NCT02861794 Recruiting - Knee Osteoarthritis Clinical Trials

Stability of Contemporary Knee Arthroplasty

Start date: May 2016
Phase: N/A
Study type: Interventional

Total joint replacement is an efficacious treatment for osteoarthritis of hips and knees. Both total knee replacement (TKR) and total hip replacements (THR) have excellent implant survivorship. However, patients' satisfaction is lower in TKR than THR. A possible cause of the discrepancy is the unnatural knee kinematics after TKR. Various implants designs have been developed to solve the problem. However, most of their designs are based on experimental data and little has been studied about their actual performance in vivo. In this study, the investigators will analyze the in vivo stability of the Global Medacta Knee Sphere (GMK Sphere) implant. Migration of the implants will be monitored with a high precision measuring method called Radiostereometric Analysis (RSA). The investigators assume the investigators study will contribute the development of more satisfying knee implants.

NCT ID: NCT02855073 Recruiting - Knee Osteoarthritis Clinical Trials

Clinical Trial to Compare ReJoinTM to Sodium Hyaluronate Injection for Knee Osteoarthritis Cartilage Defects

Start date: July 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of ReJoinTM for the Knee Osteoarthritis patients with Cartilage Defects comparing to Sodium Hyaluronate Injection.

NCT ID: NCT02851316 Recruiting - Knee Osteoarthritis Clinical Trials

Whole Body Vibration on Running Biomechanics

Start date: July 2016
Phase: N/A
Study type: Interventional

Whole body vibration (WBV) acutely improves quadriceps strength, and may improve long-term outcomes in individuals with anterior cruciate ligament reconstruction (ACLR). However, it is unclear if WBV influences athletic tasks such as running. The purpose of this study is to evaluate the influence of WBV on running biomechanics in individuals with ACLR.

NCT ID: NCT02845206 Recruiting - Knee Osteoarthritis Clinical Trials

Bespoke vs Standard Instrumentation in TKR

Start date: February 2016
Phase: N/A
Study type: Interventional

Total knee replacement (TKR) is an established treatment for knee osteoarthritis and leads to a satisfactory outcome in over 75% of patients. The pain and function after TKR can be dependent on the accuracy of initial implantation, as deviation of more than 3 degrees from the normal alignment of the limb can lead to abnormal stresses on the implant and accelerated failure. Patient specific cutting blocks may result in a more individualised implant placement, improved pain and function following surgery, and a long-lasting implant. This trial is designed to investigate if there is any benefit to bespoke instrumentation in terms of pain and function to the patient, and an economic benefit to the NHS.

NCT ID: NCT02840422 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Assessment of Patients Quality of Life Treated With Three ARTHRUM H 2% Joint Injections

ART-QUALIVIE
Start date: January 2016
Phase: N/A
Study type: Observational

The reduction of functional limits and disablilities induced by knee osteoarthritis as well as improvement of patients quality of life is a public health need registered amongst the priorities established by the French law of August 9th 2004 relative to Public Health policy. However, the response to this need is not limited to treatment with health products. This clinical trial in real life on ARTHRUM H 2% device aims to analyse patients quality of life treated by intraarticular injections, eventually for several years, by difference of usual clinical trials. This open, prospective, multicentric study aims to analyse, in patient care, the impact of three intraarticular injections of ARTHRUM H 2% on quality of life over a period of 6 months (D180) in the symptomatic treatment of knee osteoarthritis.

NCT ID: NCT02837900 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

A Study Evaluating the Safety and Efficacy of a Second Course of TPX-100 in Subjects Who Previously Received TPX-100 for Patellar Osteoarthritis Involving Both Knees

Start date: August 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability, and preliminary efficacy of a second course of TPX-100 administered by intra-articular injection to subjects with osteoarthritis of the knee who participated in study TPX-100-1.