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Knee Osteoarthritis clinical trials

View clinical trials related to Knee Osteoarthritis.

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NCT ID: NCT03082430 Enrolling by invitation - Knee Osteoarthritis Clinical Trials

GO PRP: Assessing the Efficacy of Intra Articular Injection of Platelets Rich Plasma for Gonarthrosis Treatment in Routine Care

Start date: January 19, 2017
Phase: N/A
Study type: Interventional

This monocentric protocol is designed to evaluate the efficacy of therapeutic management of symptomatic knee osteoarthritis (resistant to medical first-line treatment) by intra-articular injection of autologous PRP prepared in the same procedure and using a dedicated CE marked medical device and a validated and reproducible method of preparation

NCT ID: NCT03081663 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Quadriceps Sparing Versus Standard Total Knee Arthroplasty

Start date: May 2017
Phase: N/A
Study type: Interventional

This study is a randomized clinical trial comparing standard medial para-patellar total knee arthroplasty with a quadriceps sparing mid-vastus approach. Patients who are medically well and have a good support structure at home will be randomized to a standard or quadriceps sparing surgical approach. We will compare patient satisfaction and costs from the perspective of the Ministry of Health, the institution, society and the patient.

NCT ID: NCT03076294 Recruiting - Knee Osteoarthritis Clinical Trials

Repetitive Transcranial Magnetic Stimulation Associated With Manual Therapy in Knee Ostearthritis Pain

Start date: January 2017
Phase: Phase 2
Study type: Interventional

In this study, the investigators wondered whether the association between high frequency repetitive transcranial magnetic stimulation (hf-rTMS) and manual therapy (peripheral and central approach) is more effective in reducing pain levels and modulation of cortical activity of chronic knee ostearthritis pain subjects than manual therapy alone (usual peripheral approach). For this purpose, patients included will be submitted to one session with active or sham hf-rTMS followed by a protocol of manual therapy. Besides that another active group will have the sequence of interventions exchanged (manual therapy followed by hf-rTMS) in order to investigate whether this may influence in the final outcomes.

NCT ID: NCT03076177 Recruiting - Knee Osteoarthritis Clinical Trials

The Effectiveness of Kinesio Taping Method for Knee Osteoarthritis.

Start date: October 2014
Phase: N/A
Study type: Interventional

Purpose of our study is to evaluate effectiveness of Kinesio Taping method for knee osteoarthritis. Using simple concealed randomization procedure to form two groups (kinesio taping and control-nonspecific taping) of 100 knee osteoarthritis patients in each. 1 month all patients (depending on the group they will be allocated to) will receive either kinesio taping applications or non-specific taping: 4 applications per subject. Three times: before taping, after a month with tapes, and after 1 month without tapes evaluation of knee function, mobility, quality of life will be evaluated, including clinical examination of knee joint, measurements of knee flexion and extension by goniometer, circumference of leg over the knee, in ½ of thigh and in ½ of calf (to evaluate edema); pain will be evaluated by questionnaire, patella tendon algometry; force of calf flexors and extensors will be evaluated using Lovett manual muscle testing scale, goniometry for knee flexion/extension; for mobility, knee function, life quality evaluations - 10 Meter Walk , Five Times Sit to Stand Tests will be performed, Knee injury and Osteoarthritis Outcome Score (KOOS) and Medical Outcomes Study Short Form 36 2 version (SF-36 2v) questionnaires will be used. Also data about the need of analgesic medicament will be collected from subjects.

NCT ID: NCT03072147 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Teriparatide as a Chondroregenerative Therapy in OA

Start date: March 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate teriparatide (TP) as a chondroregenerative therapy for human knee osteoarthritis (OA). The central hypothesis to be tested is that TP supports structural modification of the joint and improves biomarker, functional and patient-reported measures of knee OA.

NCT ID: NCT03071250 Not yet recruiting - Knee Osteoarthritis Clinical Trials

An Analysis of the Outcomes From Protocolized Perioperative Care for Patients Receiving Total Hip or Knee Arthroplasty

Start date: April 1, 2017
Phase: N/A
Study type: Observational

The care for patients receiving total hip and knee arthroplasty at UAMS has followed a structured care pathway since July 2015. This system of perioperative care has focused on preoperative assessment of medical co-morbidities and risks to postoperative functional recovery, anesthetic care focused on PONV prevention and optimizing immediate postoperative functional ability, and aggressive postoperative physical therapy. This is an observational study to look at the outcomes of this program at UAMS. Areas of focus will be hospital length of stay, postoperative narcotic consumption, VAS scores, incidence of PONV, and 30-day readmission rates, and health literacy rates.

NCT ID: NCT03065738 Recruiting - Knee Osteoarthritis Clinical Trials

Effect of RO On GB During TKR Severe Varus Deformity

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Effect Of Reduction Osteotomy On Gap Balancing During Total Knee Replacement For Severe Varus Deformity

NCT ID: NCT03064139 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Mindful Walking Intervention for Knee Osteoarthritis

Start date: April 2017
Phase: N/A
Study type: Interventional

This study evaluates the feasibility of a mindful walking intervention for management of knee osteoarthritis. Half of the participants will receive the mindful walking intervention while the other half will receive education on osteoarthritis management.

NCT ID: NCT03058393 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Teach-Back for Knee Replacement Discussions

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

The goal of this study is to analyze how using the teach-back communication technique can improve patient:provider communication surrounding the discussion of knee replacement options, specifically Total Knee Arthroplasty(TKA) or a Unicompartmental Knee Arthroplasty(UKA). Orthopedic residents, fellows, physician assistants, and attendings that agree to participate will be consented and patients that have a clinical indication for a TKA and a UKA will be recruited from participating providers clinical schedules. Patient:provider interactions will be recorded and then the providers will attend a 1 hour education lecture about how to use teach-back. After attending the lecture, additional patient:provider interactions will be recorded and analyzed via a qualitative approach. Additionally, providers will participate in a semi-structured interview to capture their perceptions of teach-back and what challenges and benefits they may derive from using it.

NCT ID: NCT03058380 Not yet recruiting - Knee Osteoarthritis Clinical Trials

Stated-Preferences in Knee Arthroplasty

Start date: March 1, 2017
Phase: N/A
Study type: Observational

The primary objectives of this study are to apply best-practice stated-preference methods to quantify patient preferences for benefit-risk tradeoffs associated with arthroplasty treatment options for end-stage osteoarthritis of the knee. Duke will develop and administer stated-preference surveys to adult patients (Ages 40-80) with knee pain to collect preference data, estimate the relative importance of treatment features and outcomes, and estimate maximum acceptable risks for given benefits and minimum acceptable benefits for given harms. This study proposal describes plans for the patient stated-preference survey.