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Pain, Postoperative clinical trials

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NCT ID: NCT02154464 Not yet recruiting - Obesity Clinical Trials

Morphine-sparing Effect of Intravenous Paracetamol for Post-operative Pain Management Following Laparoscopic Gastric Banding in Morbidly Obese Patients

Start date: June 2014
Phase: N/A
Study type: Interventional

The investigators predict that giving patients paracetamol in the operative period will reduce their need for opioid pain reducers in the post operative setting.

NCT ID: NCT01909765 Not yet recruiting - Postoperative Pain Clinical Trials

Two Different Surgical Techniques on Postoperative Circumcision Pain

Start date: July 2013
Phase: Phase 4
Study type: Interventional

To compare the effect of two different surgical techniques, the dorsal slit and double incision technique, on postoperative pain.

NCT ID: NCT01711229 Not yet recruiting - Pain, Postoperative Clinical Trials

Equality Study of Ofirmev vs Oral Acetaminophen

Start date: December 2015
Phase: Phase 4
Study type: Interventional

Acetaminophen (Tylenol) is a drug that is used commonly for relief of mild to moderate pain. It is found in many pain medicines that people take after having surgery. Narcotics are other drugs also used for pain (examples of narcotics are morphine and related pain medications). Medical science knows for a fact that acetaminophen works well when taken with narcotics for moderate to severe pain. Recently, acetaminophen has become available in an intravenous (IV) form called Ofirmev®. The IV form means that acetaminophen can be given into a vein. The benefits of getting medicine from an IV include: - making the medicine work quickly - less medicine having to pass through the liver to be changed into a form that your body can process The investigators know that acetaminophen is helpful for pain relief at the time of surgery and after surgery. Acetaminophen is a very popular drug in outpatient surgery for pain control when patients go home. The patient's surgeon uses it to control pain after surgery at home in the form of Lortab or Percocet (Lortab and Percocet also have a narcotic medicine that mixes with acetaminophen). Also, currently at Surgicare, some anesthesiologists give intravenous acetaminophen while the patient is waiting to go to surgery. The investigators currently do not give any patient acetaminophen by mouth BEFORE surgery. However, since the addition of the IV form to the drug market, there has been interest to see if the oral form is just as good or better in reducing pain after surgery. This is why we are asking patients to join our study. The goal of this study is to find out if the oral form (by mouth) or the IV form (given into a vein) of acetaminophen controls pain after surgery better.

NCT ID: NCT01614236 Not yet recruiting - Clinical trials for Multimodal Analgesia

Pre- Versus Post-Incisional Pregabalin for Postoperative Pain Control

Start date: July 2012
Phase: N/A
Study type: Interventional

Proper pain relief is a major concern of patients worldwide. Preoperatively, one of the most common questions asked by patients pertains to the amount of pain they will experience after surgery how long it will last and how good will it be controlled. Pain concerns the surgical team as well, because of its correlation with clinical outcomes and patients' satisfaction rate . Studies have shown that negative clinical outcome with regard to pain control includes decreases in vital capacity and alveolar ventilation, pneumonia, tachycardia, hypertension, myocardial ischemia, transition into chronic pain, poor wound healing, and psychological sequelae .

NCT ID: NCT01547663 Not yet recruiting - Pain, Postoperative Clinical Trials

A Comparison of Pain Scales in Patients With Disorder of Consciousness Following Craniotomy

Start date: March 2012
Phase: N/A
Study type: Observational

This study aims to test validity, reliability and practicality of translated NCS, CNPI and FLACC in unconscious patients in 48 hour following craniotomy.

NCT ID: NCT01491191 Not yet recruiting - Clinical trials for Chronic Post-operative Pain

Palmitoylethanolamide for Post-operative Pain Prevention

PEAforCPSP
Start date: January 2012
Phase: N/A
Study type: Interventional

Postsurgical pain becomes chronic when it lasts more then two months after surgery. A neurogenic or neuropathic pathogenesis is hypothesized for this event that reaches high rates after urologic and gynecologic surgeries. Palmitoylethanolamide (PEA) binds to mast cells and regulates pro-inflammatory factors release, without adverse events. The investigators assume that perioperative administration of PEA can reduce chronic postsurgical pain incidence of patients undergoing to urologic and gynecologic elective surgery.

NCT ID: NCT01359059 Not yet recruiting - Postoperative Pain Clinical Trials

Pre- Versus Post-incisional Pregabalin for Postoperative Pain Attenuation and Analgesics Spare in Orthopedic Oncologic Patients

Start date: June 2011
Phase: N/A
Study type: Interventional

Hypothesis No studies considered the comparison of preemptive vs. post-surgery Pregabalin (PGL) only administration. The investigators believe that the administration of PGL preemptively would diminish pain sensation and therefore the need for opioids administration in orthopedic-oncologic patients more effectively than if administered starting postoperatively.

NCT ID: NCT01329120 Not yet recruiting - Pain, Postoperative Clinical Trials

Short and Long-term Effects of Surgical Repair of Pectus Deformities

Start date: September 2015
Phase: N/A
Study type: Observational

A large number of institutions have reported their early results with minimally invasive repair of pectus excavatum and open repair of pectus carinatum, but only few have addressed the outcomes relevant to the concerns of the patients and even fewer have reported long-term results following bar removal. Even fewer studies have investigated the prevalence and characteristics of long term persistent post-surgical pain following surgical repair of pectus deformities. The reasons as to why acute postoperative pain in some patients persists and becomes chronic whereas in others the pain dies down shortly after wound healing are largely unknown, and why some patients complain of loss of sensibility in wide regions of their chest following surgery also remains unclear.

NCT ID: NCT01291979 Not yet recruiting - Postoperative Pain Clinical Trials

The Effect of Intravenous Lidocaine on Pain After Tonsillectomy

Start date: February 2011
Phase: Phase 4
Study type: Interventional

This prospective randomized study aims to evaluate the effectiveness of intravenous lidocaine injection on the relief of pain in patients undergoing tonsillectomy. A total of 62 patients will be randomized into one of two groups (group C or group I) based on Excel number generation. Patients in group C will receive received normal saline intravenous injection, and patients in group I will receive an intravenous bolus injection of 1.5 mg/kg lidocaine followed by a continuous lidocaine infusion of 2 mg/kg/hr. Visual analogue scale pain scores, fentanyl consumption and the frequency at which patients pushed the button (FPB) of a patient-controlled analgesia system will be recorded at 4, 12, 24, 48 hours postoperatively.

NCT ID: NCT01278264 Not yet recruiting - Post Operative Pain Clinical Trials

Transversus Abdominis Plane Blocks With Abdominoplasty

TAPA
Start date: June 2011
Phase: Phase 4
Study type: Interventional

Comparing morphine consumption and recovery with two different TAP block techniques after abdominoplasty.