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Pain, Postoperative clinical trials

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NCT ID: NCT01589796 Recruiting - Adult Clinical Trials

Medial Versus Traditional Approach to US-guided TAP Blocks for Open Inguinal Hernia Repair

Start date: April 2012
Phase: N/A
Study type: Interventional

Pain relief after open inguinal hernia repair could be improved by administration of TAP block or ilioinguinal/iliohypogastric nerve block. It is unclear which one works better. The investigators hypothesize that doing TAP block closer to the middle of the abdomen would result in improved pain relief due to simultaneous block of ilioinguinal/iliohypogastric nerves.

NCT ID: NCT01586741 Completed - Recurrence Clinical Trials

A Study to Evaluate Two Different Surgical Methods for Treatment for Abdominal Wall Diastasis

Start date: December 2009
Phase: N/A
Study type: Interventional

This is a three armed prospective randomized trial that will compare two different surgical techniques for reconstruction of the abdominal wall diastasis with a conservative treatment procedure. The study hypothesis: Which surgical approach provides the safest and best long term results for patients with abdominal wall diastasis either the insertion of net alternative with a double row suture or exercise alone?

NCT ID: NCT01582490 Completed - Postoperative Pain Clinical Trials

Study of EXPAREL in Patients Undergoing Breast Augmentation

Start date: April 2012
Phase: Phase 4
Study type: Interventional

This is a Phase 4, prospective, open-label, non-randomized, sequential study with two treatment groups differing only in the technique used for EXPAREL administration (instillation or infiltration).

NCT ID: NCT01582477 Completed - Analgesia Clinical Trials

TAP-patients With Robotic Assisted Lap Prostatectomy

TAP
Start date: March 2012
Phase: Phase 4
Study type: Interventional

The purpose of the study is to assess the safety and efficacy of EXPAREL when administered via infiltration into the transversus abdominis plane (TAP) to prolonged postsurgical analgesia in men undergoing robot-assisted laparoscopic prostatectomy.

NCT ID: NCT01579786 Active, not recruiting - Post Operative Pain Clinical Trials

Treatment of Post Operative Pain in Thyroid Surgery Patients: Perspective Study Acupuncture Versus Drugs

Start date: May 2011
Phase: N/A
Study type: Interventional

The aim of the study was to evaluate if acupuncture may reduce intraoperative ULTIVA (remifentanil) consumption and post operative pain measured with VAS, italian version Mc Gill Questionnaire Pain and drug consumption (acetaminophen daily consumption).

NCT ID: NCT01579747 Completed - Postoperative Pain Clinical Trials

Does Ultrasound Improve Procedural Time in the Lateral Popliteal Approach to the Sciatic Nerve in Obese Patients

Start date: July 2012
Phase: Phase 4
Study type: Interventional

Ultrasound have been shown to improve the time needed to locate and block nerves in the non obese population. However, its utility is still unknown in the obese population. Ultrasound is known to produce poorer quality images in the obese population. This study aims to find out if it is a better tool for nerve localization compared to the traditional nerve stimulation technique.

NCT ID: NCT01577940 Completed - Postoperative Pain Clinical Trials

Method Study: Bilateral TAP Block With 24 Hours Infusion

Start date: January 2011
Phase: Phase 4
Study type: Interventional

The purpose of this method study in healthy volunteers is to determine the extent of sensory block following Transversus Abdominis Plane (TAP) block with 24 hours infusion of ropivacaine versus infusion of saline. Furthermore, to determined the analgesic effect of the TAP block and the influence on the lung function.

NCT ID: NCT01566838 Completed - Postoperative Pain Clinical Trials

Continuous Subpleural Infusion of Bupivacaine

Start date: October 2012
Phase: N/A
Study type: Interventional

Rationale: For the past 3 years the investigators have routinely used an axial subpleural tunneling technique that del Study Design: All patients over the age of 18 having an isolated thoracoscopic procedure performed at Inova Fairfax Hospital for therapeutic or diagnostics purposes will be screened. Patients will be excluded if they have: previous ipsilateral thoracic surgery, need for operative pleurectomy or pleurodesis, chronic use of pain medication, sedatives or hypnotics, drug allergies, liver dysfunction, renal dysfunction, history of peptic ulcerative disease, sleep apnea in need of Bipap, severe chronic obstructive pulmonary disease (COPD), inability to consent, or are pregnant. All patients included will be screened, consented, and operated on by the one year anniversary of institutional review board (IRB) approval. Study Methodology: Eighty-six consented patients will be randomized into the study arm (use of a pain catheter with 0.125% bupivacaine) or the standard of care group (no pain catheter). The primary outcome is the use of narcotic pain medication post-operatively, compared between study groups. Secondary outcomes will include postoperative pain scores, hospital and length of stay. The On-Q pump delivers local anesthetic to the intercostal space, without leakage elsewhere, creating a functional multi level rib block. Despite positive subjective results, objective data is lacking. The investigators have also noted that some patients develop an annoying short term paresthesia that has been minimized by using lower anesthetic concentrations than described in other publications. Objectives: To evaluate visual analog pain scores post-operatively up to 30 days post-operative, and to determine any association between pain management and length of stay. Study Type: A prospective randomized 2-arm study will be performed. Statistical Methodology: Total amount of narcotic pain medication administered through postoperative day 7, will be compared between the study groups using student's t-tests and Wilcoxon rank-sum tests. Secondary outcomes, overall sum of pain scores through postoperative day 7, then at day 30 post-operatively, hospital length of stay, and overall hospital cost, will also be compared among study groups using student's t-tests and Wilcoxon rank-sum tests.

NCT ID: NCT01564680 Completed - Postoperative Pain Clinical Trials

Lornoxicam vs. Paracetamol After Lower Abdominal Surgery

Start date: March 2009
Phase: Phase 4
Study type: Interventional

Background: The aim of this prospective, randomized, double-blind study is to determine the most effective supplemental analgesic, paracetamol or lornoxicam for postoperative pain relief after lower abdominal surgery. Methods: Sixty patients scheduled for lower abdominal surgery under general anesthesia were randomly allocated to receive either isotonic saline (Control group), intravenous paracetamol 1 g every 6 h (Paracetamol group) or lornoxicam 16 mg then 8 mg after 12 h (Lornoxicam group). Additionally pain was treated postoperatively using morphine patient-controlled analgesia. Postoperative pain scores measured by the verbal pain score (VPS), morphine consumption and the incidence of side effects were measured at 1, 2, 4, 8, 12 and 24 hours postoperatively.

NCT ID: NCT01562691 Completed - Clinical trials for Postoperative Respiratory Complications

Effect of Airway Integrated Nasal Packing With Different Material

Start date: June 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the effect of integrated airway in nasal packing material foe patients receiving nasal septoplasty surgery.