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Pain, Postoperative clinical trials

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NCT ID: NCT05308797 Completed - Postoperative Pain Clinical Trials

Combine Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Coronary Bypass Surgery

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Even though Erector Spinae Plane (ESP) Block is shown to be efficient in cardiac surgery, the Combine Serratus Anterior Plane (CSAP) Block is still controversial if it has an efficient analgesic effect for sternotomy and drain tube pain relief. This study aims to compare ESP block and CSAP block for postoperative analgesia in coronary bypass surgery patients.

NCT ID: NCT05308420 Completed - Postoperative Pain Clinical Trials

PENG Block vs Intrathecal Morphine in Total Hip Arthroplasty

Start date: April 3, 2022
Phase: Phase 4
Study type: Interventional

To compare the impact of pericapsular nerve group (PENG) block to intrathecal morphine on postoperative analgesia, motor function and side effects in patients undergoing primary total hip arthroplasty under spinal anesthesia.

NCT ID: NCT05306535 Completed - Post Operative Pain Clinical Trials

Effect of Occlusal Reduction on Relief of Pain and Sensitivity to Percussion in Patients With Irreversible Pulpitis

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

One of the most important aspects of endodontic practice is to abate pain during and post root canal treatment. An endodontist by all means should provide a painless endodontic treatment to their patients. This study is carried out to determine the effect of occlusal reduction on relief of pain and percussion in patients with irreversible pulpitis and symptomatic apical periodontitis treated in a single visit root canal treatment. Pain will be assessed preoperatively and then post operatively after completion of the root canal at 6 hours, 12 hours, 24 hours, 48 hours and 72 hours following obturation of root canal.

NCT ID: NCT05303688 Completed - Pain, Postoperative Clinical Trials

Does Preventive Dexketoprofen Reduce Pain After Orthognathic Surgery

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

Background The purpose of this study was to evaluate the effect of a single-dose intravenous dexketoprofen administration for preventive analgesia on postoperative pain and reducing swelling in double jaw surgery. Material and Methods The authors designed a prospective, randomized, and double-blind cohort study. Patients who have Class III malocclusion were randomly divided in two groups. 50 mg intravenous dexketoprofen trometamol were administrated 30 minutes before incision in treatment group, while intravenous sterile saline was administrated 30 minutes before incision in placebo group. The primary predictor variable was treatment group. Primary outcomes were pain, swelling and 24-hour opioid intake. Patient- controlled analgesia with tramadol was given for management of postoperative pain. Other variables were demographic and operation related parameters. Visual analogue scale was used to evaluate postoperative pain. 3dMD Face System (3dMD, USA) was used to measure postoperative swelling. Data were analysed using two independent samples t test and Mann Whitney U test.

NCT ID: NCT05300854 Completed - Post Operative Pain Clinical Trials

Serratus Block Versus Paravertebral Block for Post Thoracotomy Pain Relief

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This double-blinded, randomized controlled study was done on 60 patients older than 18 years undergoing thoracotomy. Patients were allocated into two equal groups (30 patients each). Group S: Standard anesthesia in addition to SPB. II. Group P: Standard anesthesia in addition to PVB.

NCT ID: NCT05299788 Completed - Pain, Acute Clinical Trials

Post-thoracotomy Pain Management With Active External Warming and Ice Application

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption. The research is a quasi-experimental design with control and study groups.

NCT ID: NCT05299021 Completed - Postoperative Pain Clinical Trials

Serratus Anterior Plane Block for Modified Radical Mastectomy: Double-point VS Single-point

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Nowadays, the incidence of breast cancer is the first number of malignant tumors, and the primary treatment method is surgery. As is known to all, less postoperative complications and enhanced recovery are closely related to effective analgesia. However, postoperative patients often experience moderate pain, while associated with axillary discomfort. Serratus Anterior Plane Block (SAPB) relieves postoperative pain, but traditional single point block method has no effect on axillary discomfort. Therefore, it is necessary to try double point blocks to explore their impact on postoperative analgesia and axillary comfort. This RCT will recruit patients proposed to undergo Modified Radical Mastectomy (MRM) and be randomized to single point or double point groups to evaluate their postoperative pain score and axillary comfort in order to provide clinical guidance.

NCT ID: NCT05291715 Completed - Pain, Postoperative Clinical Trials

The Effect of Ozone Therapy on Pain Perception After Free Gingival Graft Surgery in Patients With Mucogingival Defects

Start date: June 15, 2022
Phase: N/A
Study type: Interventional

Gaseous ozone (O3-triatomic oxygen) is the third-strongest oxidizing agent worldwide. It influences the cellular and the humoral immune system, by stimulating the proliferation of immunocompetent cells and the synthesis of immunoglobulin. Additionally; biologically active substances, such as interleukins, leukotrienes and prostaglandins which are beneficial in reducing inflammation and wound healing are orchestrated following ozone application. Given that after harvesting of a free gingival graft from the palatal donor site, healing occurs by secondary intention process; for patients with mucogingival conditions. The investigators will compare the natural process of healing at the donor site versus the healing process consecutive to ozone application; with the primary outcome is to evaluate the postoperative pain perception using visual analogue scale and to estimate the consumption of analgesics tablets after surgery.

NCT ID: NCT05289791 Completed - Clinical trials for Symptomatic Irreversible Pulpitis

Effect of Ultrasonic Activation of Bioceramic Sealer on Postoperative Pain in Lower Premolars

Start date: April 8, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to clinically compare post-operative pain levels after ultrasonic activation of Ceraseal bioceramic sealer versus non-activated bioceramic sealer for patients with symptomatic irreversible pulpitis related to mandibular premolar teeth.

NCT ID: NCT05288374 Completed - Pain, Postoperative Clinical Trials

Celecoxib in Postoperative Analgesia for Radius Fracture Surgery

Start date: February 10, 2022
Phase: Phase 4
Study type: Interventional

Patients scheduled for elective osteosynthesis of the distal radius will be randomized to receive celecoxib 100 mg orally (PO) at 6 in the morning before surgery and every 12 hours for 2 days thereafter, or a placebo pill in the same regimen. After surgery under general anaesthesia, they will receive paracetamol 1 g intravenously (IV) every 6 hours and if pain intensity is greater than 4 on a numeric rating scale (NRS) of 0-10, piritramid 15 mg intramuscularly (IM) will be administered. Pain intensity, piritramid consumption and side effects of treatment will be recorded in a questionnaire for 2 days.