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Pain, Postoperative clinical trials

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NCT ID: NCT03248648 Completed - Postoperative Pain Clinical Trials

Efficacy of Intra-articular Neostigmine Versus Ketamine for Postoperative Analgesia in Arthroscopic Knee Surgery

Start date: March 1, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

To compare the efficacy of intra-articular administration of neostigmine versus ketamine as adjuvant analgesics after knee arthroscopy.

NCT ID: NCT03245359 Completed - Pain, Postoperative Clinical Trials

Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks

Start date: September 28, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if there is any significant difference between using a short-term ON-Q nerve block (which is applied prior to surgery and maintained in place until the medication in the initial balls have been fully used, usually 2-4 days) in comparison to a long-term ON-Q nerve block (which is applied prior to surgery and maintained in place up to seven days after surgery). This study will analyze patient reported levels of pain, range of motion, and narcotic use, as well as investigate whether blood loss, blood thinners, and hemoglobin/hematocrit blood levels influence patient pain levels. This study will compare patient-reported pain, range of motion and narcotic use in total knee arthroplasty patients who receive the short-term and long-term combination nerve block (saphenous and posterior of the adductor canal and wide-field posterior knee.

NCT ID: NCT03244540 Completed - Pain, Postoperative Clinical Trials

Regional Analgesia After Cesarean Section

Start date: September 4, 2017
Phase: Phase 4
Study type: Interventional

All patients will be anaesthetized with spinal technique. Each patient will be treated with intravenous morphine - patient controlled analgesia (PCA). 2 of 3 groups of patients will receive ultrasound-guided transversus abdominis plane or quadratus lumborum block to treat postoperative pain. Postoperative pain will measured with visual-analogue scale (VAS). Total morphine consumption and time to the first demand will be noted. 1, 2, 6 months after surgery each patient will be called to assess neuropathic pain with Neuropathic Pain Symptom Inventory (NPSI).

NCT ID: NCT03243279 Completed - Atrial Fibrillation Clinical Trials

BRS and Outcomes in Cardiothoracic Surgery

Start date: September 15, 2017
Phase:
Study type: Observational

The purpose of this study is to determine whether baroreceptor sensitivity (the ability of your body to change your heart rate and/or blood pressure in response to a situation) has any effect on how likely you are to suffer certain events after heart or lung surgery. The postoperative events that the investigators will be studying are pain after surgery, atrial fibrillation (an irregular heart rhythm), and cognitive dysfunction (a decline in mental abilities).

NCT ID: NCT03243032 Withdrawn - Pain, Postoperative Clinical Trials

Pre-Emptive Analgesia in Dental Implant Surgery

Start date: October 6, 2017
Phase: Early Phase 1
Study type: Interventional

To determine the clinical effectiveness of combined use of pre-emptive analgesia and long acting anesthesia for pain suppression following dental implant surgery as measured by a validated numerical rating scale and the information related to consumption of post-operative medications.

NCT ID: NCT03242668 Completed - Pain, Postoperative Clinical Trials

Paravertebral Block for Postoperative Analgesia in Thoracoscopic Surgery

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

To access the analgesic efficacy of patient controlled thoracic paravertebral analgesia.

NCT ID: NCT03241875 Completed - Pain, Postoperative Clinical Trials

Effects of Preoperative Gabapentin Versus Pregabalin on Shoulder Pain After Laparoscopic Cholecystectomy

Start date: December 1, 2016
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate the effect of premedication with pregabalin or gabapentin versus placebo on postoperative shoulder pain after laparoscopic cholecystectomy.

NCT ID: NCT03240562 Completed - Postoperative Pain Clinical Trials

Ultrasound-guided Block for Thoracic Surgery Pain

Start date: August 3, 2017
Phase: N/A
Study type: Interventional

The investigators aimed to assess Ultrasounde- guided serratus anterior plane block can be effective in acute postoperative pain following thoracic surgery.

NCT ID: NCT03238430 Completed - Pain, Postoperative Clinical Trials

Management of Pain Post Hepatectomy : Infiltration of Local Anesthetics Versus Continuous Spinal Analgesia .

CATHEPAT
Start date: May 20, 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Analgesia in liver surgery is a challenge, postoperative coagulopathy risk raises fears an epidural haematoma formation following the epidural analgesia, "gold standard" in major abdominal surgery. The spinal analgesia and/or continuous wound infiltration of local anesthetics constitute so an alternative. The study will compare the continuous infiltration of local anesthetics and rachianalgesia in terms of decreased postoperative morphine consumption and incidences of chronic postoperative pain at 3 and 6 months after hepatic surgery compared to the control group.

NCT ID: NCT03237481 Completed - Postoperative Pain Clinical Trials

Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)

Start date: July 31, 2017
Phase: Phase 3
Study type: Interventional

This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in subjects undergoing unilateral open inguinal herniorrhaphy.