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Pain, Postoperative clinical trials

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NCT ID: NCT03312153 Not yet recruiting - Pain Clinical Trials

Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effect of Neem (azadirachta indica) and 2.5% sodium hypochlorite as root canal irrigants on the intensity of post-operative pain and the amount of endotoxins in necrotic teeth.

NCT ID: NCT03311737 Recruiting - Postoperative Pain Clinical Trials

Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery

CDAAMIUVLS
Start date: September 19, 2017
Phase: Phase 1
Study type: Interventional

This is a single center, randomized, single blind study to compare the analgesic effect of different anesthesia and postoperative analgesic methods in uniportal VATS lung surgery.

NCT ID: NCT03309267 Completed - Pain, Postoperative Clinical Trials

Serratus Anterior Plane Block Versus Intercostal Block

Start date: October 6, 2017
Phase: N/A
Study type: Observational

Pain after thoracotomy is the most severe pain experienced by the patient. Good pain control after the operation provides comfortable respiration and reduces the development of chronic pain and complications. we aimed to compare SAPB with IBregarding postoperative visual analog scale (VAS) scores and analgesic consumption in patients undergoing thoracotomy operation.

NCT ID: NCT03308955 Completed - Postoperative Pain Clinical Trials

Analgesic Effect of Quadratus Lumborum Block Application After Laparoscopic Cholecystectomy Surgery

Start date: August 22, 2017
Phase: N/A
Study type: Interventional

Laparoscopy is frequently used today for intraabdominal operations. Laparoscopic procedure has become the treatment of choice for many patients with symptomatic cholelithiasis. Patients undergoing laparoscopic cholecystectomy suffer from acute postoperative pain, despite a multimodal analgesic regime. This is a randomised controlled trial efficay of the Quadratus Lumborum (QL) Block in terms of analgesic efficacy in patients who undergo laparoscopic cholecystectomy.

NCT ID: NCT03306953 Completed - Pain, Postoperative Clinical Trials

The Effect of Rectus Muscle Approximation at Cesarean Delivery on Pain Perceived After Operation

Start date: October 11, 2017
Phase: N/A
Study type: Interventional

This is a prospective randomized controlled study to determine the clinical outcome of rectus muscle re-approximation at Cesarean delivery.

NCT ID: NCT03304444 Recruiting - Post Operative Pain Clinical Trials

A Comparison of Exparel to Bupivacaine in TAP Block for Abdominal Gynecologic Surgery

Start date: August 2016
Phase: Phase 3
Study type: Interventional

This study evaluates the comparison between liposomal bupivacaine versus bupivacaine HCl in Transversus Abdominis Plane blocks for gynecologic surgery on the length of stay in the hospital, total narcotic use, and overall complications rates.

NCT ID: NCT03303651 Completed - Pain Clinical Trials

Monitor-Guided Analgesia During General Anesthesia - Part I

MOGADA
Start date: October 16, 2017
Phase: N/A
Study type: Interventional

This prospective randomized clinical trial evaluates the effects of a monitor-guided opioid analgesia during general anesthesia. To date no standard-monitoring device exists to specifically reflect the analgesic component of general anesthesia. Quality and safety of general anesthesia are of major clinical importance and should be improved by limiting the opioid analgesic's dosage to the minimum amount needed. The study compares the effects of monitoring nociception during general anesthesia with different innovative techniques in comparison to routine clinical practice.

NCT ID: NCT03302689 Active, not recruiting - Pain, Postoperative Clinical Trials

Comparison Levobupivacaine and Ropivacaine for TAP-block After Caesarean Section

Start date: September 25, 2017
Phase: N/A
Study type: Interventional

Randomized, double-blind, controlled trial: a comparison of Levobupivacaine and Ropivacaine for postoperative analgesia using TAP-block Objectives: 1. VAS score during the first 12 hours 2. Determine which drug is more effective for postoperative analgesia in the first 12 hours after surgery 3. Side effects

NCT ID: NCT03301610 Completed - Pain, Postoperative Clinical Trials

Mobile Educations Effect on Pain Outcomes

Start date: October 23, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to explore the clinical impact of pain management education using a mobile web-based education delivery system compared to standard education delivery. This study seeks to understand the difference between two different education delivery methodologies and the effect on the postoperative pain experience, including participation in treatment plan, knowledge, pain outcomes, and opioid requirements in patients undergoing major hip (THA) and knee (TKA) arthroplasty. It is hypothesized that a real-time, interactive, mobile education system will demonstrate improved pain associated outcomes and higher patient participation when compared to the current standard education delivery method.

NCT ID: NCT03298711 Completed - Pain, Postoperative Clinical Trials

Central Sensitization and Alteration of Circulating Neurosteroid

Start date: November 20, 2017
Phase:
Study type: Observational

For patients who underwent two-stage replacement of both knee joints (one knee surgery - one week term- the other knee surgery), postoperative pain and analgesic usage with patient-controlled analgesia (PCA) increased at the second stage, which suggests that central sensitization occurs within a short period (one week) in patients who undergo total knee arthroplasty (TKA). Neurosteroids act on NMDA and AMPA receptors, GABAa receptors, and voltage-dependent Ca2+ or K+ channels of sensory neurons to increase invasive or neuropathic pain and, conversely, to exhibit analgesic and anticonvulsant effects. These actions mean that the neurosteroid acts as an endogenous regulator of pain control and central sensitization. The purpose of this study is to confirm that the hypothalamus-pituitary-adrenal (HPA) axis, which is the main body of endocrine neurosteroid, is associated with increased pain sensitivity after TKA. The concentrations of cortisol and dehydroepiandrosterone (DHEA) in the saliva of patients who undergo two-staged bilateral knee replacement surgery (one knee surgery - one week term- the other knee surgery) will be measured at each stage and analyzed for correlation between concentration-related changes of HPA and postoperative knee pain variations.