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Pain, Postoperative clinical trials

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NCT ID: NCT03570996 Terminated - Pain, Postoperative Clinical Trials

A Trial Comparing Transversus Abdominis Plane Catheter Versus Epidural After Esophagectomy

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

A randomized trial comparing perioperative outcomes between bilateral transversus abdominis plane TAP catheters with patient controlled analgesia (PCA) to epidural for esophagectomy patients with a VATS chest approach. Further objectives are to determine pain requirements between multiple modalities of pain control and compare the subsequent sequelae of narcotic use and blood pressure control and to compare complications such as anastomotic leak, atrial fibrillation and perioperative morbidity and mortality between the two groups.

NCT ID: NCT03570541 Completed - Postoperative Pain Clinical Trials

TQL-block for Laparoscopic Hemicolectomy

Start date: June 28, 2018
Phase: Phase 4
Study type: Interventional

Every year 350 patients undergo surgery due to colorectal cancer at Zealand University Hospital, Roskilde. The majority of the surgeries are performed using a minimal invasive laparoscopic technique where the bowl anastomosis is either hand sown or stapled. The procedure is performed, while the patient is under general anaesthesia. An observational prospective survey from 2016-17 of sixty patients undergoing hemicolectomy at Zealand University Hospital, Roskilde has shown, that even though the patients are subjected to a multimodal analgesic regimen, a substantial amount of opioids are being administered during the first 24 hours post surgery; i.e. 51.91 mg ± 36.22 mg (Mean ± SD) of oral morphine equivalents. Sixty-five percent of the patients receive opioids at the PACU. Their maximum pain score at the PACU is registered, using a numerical rating scale of 0-10, as 3.28 ± 2.65 (Mean ± SD). So it is obvious that there is room for improvement and a reduction in the use of postoperative opioids. Thus, there is a clearly defined research problem to explore. Currently ultrasound-guided nerveblocks are not part of the multimodal analgesic regimen. The primary aim of this study is to investigate the efficacy of the ultrasound-guided bilateral transmuscular quadratus lumborum block on reducing postoperative opioid consumption.

NCT ID: NCT03566433 Completed - Inguinal Hernia Clinical Trials

Postoperative Pain After Endoscopic TEP vs. Lichtenstein Hernioplasty in Inguinal Hernia Repair

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

Immediate pain reaction and return to work after TEP or Lichtenstein hernia repair have not been studied. In this multicenter trial the patients are allocated to surgery using TEP (n=50) or Lichtenstein (n=50) technique. Pain and return to work are recorded postoperatively up to one month. Immediate and late complications are also analyzed.

NCT ID: NCT03565705 Completed - Pain, Postoperative Clinical Trials

Spinal Anesthesia and Peri-operative Opioid Consumption in Open Abdominal Prostatectomy

SAPOC
Start date: April 24, 2018
Phase:
Study type: Observational

Retrospective analysis to assess the impact of spinal anesthesia on peri-operative opioid consumption during open abdominal prostatectomy. The authors compare the group that had spinal anesthesia in combination with propofol sedation and a laryngeal mask to the second group that underwent the same procedure in general anesthesia with tracheal intubation.

NCT ID: NCT03565640 Completed - Postoperative Pain Clinical Trials

Anchorsure Versus Capio for Sacrospinous Ligament Fixation

Start date: October 29, 2018
Phase: N/A
Study type: Interventional

Sacrospinous ligament fixation is a common method of repairing apical support for pelvic organ prolapse but it currently suffers from a high rate of postoperative buttock and posterior thigh pain. Anchorsure® is a relatively new FDA-approved device that uses an anchor instead of the widely-used suture capturing mechanism to perform sacrospinous ligament fixation. The study hypothesis is that Anchorsure® will reduce the degree and rate of buttock and posterior thigh pain compared to the widely used Capio™ Slim suturing capturing Device.

NCT ID: NCT03562611 Completed - Pain Clinical Trials

Postoperative Pain and Discomfort After Orbital Decompression

Start date: June 8, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the postoperative pain and discomfort using flurbiprofen axetil or nalbuphine administration after orbital decompression under general anesthesia.

NCT ID: NCT03560362 Recruiting - Lung Cancer Clinical Trials

Postoperative Pain Control With Lipossomic Extended Release Bupivacaine

Start date: July 9, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Randomized trial of intraoperative intercostal block with bupivacaine with epinephrine compared to lipossomal extended release bupivacaine.

NCT ID: NCT03559140 Completed - Post-operative Pain Clinical Trials

Reduction of Post-endodontic Pain After 3 Irrigation Regime

RPEP
Start date: January 4, 2018
Phase: N/A
Study type: Interventional

The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using there irrigating regime. Methodology: All 216 patients had upper or lower molar, premolar or anterior teeth selected for conventional RCT for prosthetic reasons detected with only vital pulps. Of the sample of 216 teeth, were selected to just one method for instrumentation and different manner to irrigate. All instruments were used with a micro motor (VDW, Munich Germany). Reciproc instruments. Final irrigation with cold (8oC, 2.5 oC and room temperature 17% EDTA and saline solution served as a lubricants.

NCT ID: NCT03559127 Completed - Post Operative Pain Clinical Trials

Pain Reduction Using Two Cold Irrigating Protocols in Teeth With Vital Pulps.

EP18
Start date: March 7, 2018
Phase: N/A
Study type: Interventional

The goal of this clinical research was to relate the incidence of post-endodontic pain after one-visit root canal treatment using two cold protocols of irrigation. Methodology: All 240 patients had upper or lower molar, premolar or anterior teeth selected for conventional root canal treatment for prosthetic reasons detected with only vital pulps (symptomatic or asymptomatic condition). Of the sample of 240 teeth, were selected to different manner to irrigate. Reciproc instruments were used with a micro motor (VDW, Munich Germany). Final irrigation with cold (6oC, 2.5 oC and room temperature 17% EDTA and saline solution served as a lubricants.

NCT ID: NCT03558880 Completed - Pain, Postoperative Clinical Trials

Ultrasound Guided Bilateral Erector Spinae Plane Block Versus Tumescent Anesthesia

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

In breast reduction surgery, pain control is usually performed with tumescent anesthesia, thoracic epidural anesthesia, intercostal nerve blocks and paravertebral block applications. Tumescent anesthesia is also preferred by plastic surgeons because of the varying risk of thoracic epidural anesthesia and paravertebral block applications. After the Erector spinae block was first described by Forero in 2016, it was reported to have been applied in many cases, including breast surgery. It is considered to be a safer block because of the presence of paravertebral block-like activity and the location where the needle is guided away from the pleura. The investigators aimed to compare postoperative analgesia consumption, pain scores and patient satisfaction of erector spine block with tumescent anesthesia in patients who underwent reduction mammoplasty operation under general anesthesia in this double-blind prospective randomized study.