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Pain, Postoperative clinical trials

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NCT ID: NCT04776369 Active, not recruiting - Postoperative Pain Clinical Trials

Effect of Lidocaine Versus Magnesium on Postoperative Pain in Spine Surgery

Start date: May 1, 2022
Phase: Phase 4
Study type: Interventional

The goal in this work is to compare the effect of intravenous single-bolus lidocaine infusion versus intravenous single-bolus magnesium sulfate infusion on postoperative pain, emotional status and quality of life in patients undergoing spine fusion surgery.

NCT ID: NCT04775992 Not yet recruiting - Clinical trials for Acute Postoperative Pain

Preemptive Analgesia of Gabapentoids in Orthopedic Surgery

Start date: March 1, 2021
Phase:
Study type: Observational

To address the preemptive analgesic effect of preoperative gabapentoids versus no gabapentoids in orthopedic surgery

NCT ID: NCT04774965 Not yet recruiting - Surgery Clinical Trials

The Effects of SlumberCurve™ Following Rotator Cuff Surgery: A Randomized Control Trial

Start date: June 30, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of a novel sleep aid known as SlumberCurve™, which serves as an adjustable form of a wedge pillow, on sleep quality and pain management following rotator cuff repair. The researchers hypothesize that SlumberCurve™ will significantly improve sleep quality and reduce night-time pain.

NCT ID: NCT04774328 Completed - Postsurgical Pain Clinical Trials

Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair

Start date: September 9, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

A Three-Part, Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Adaptive Safety, Pharmacokinetics, and Preliminary Efficacy Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair

NCT ID: NCT04773509 Completed - Scoliosis Clinical Trials

Effect of Intraoperative Paravertebral Block on Postoperative Pain and Recovery in Patients Undergoing Mechanical Correction for Scoliosis

Start date: June 24, 2021
Phase: N/A
Study type: Interventional

Pain management after scoliosis surgery is challenging for the anesthesiologists. This surgery causes severe postoperative pain and patients undergoing these operations are children or adolescents who are increased pain sensation compared with adults. Therefore, we aim to evaluate whether intraoperative paravertebral block (PVB) decreases postoperative pain in these patients. Thirty-two patients scheduled for mechanical correction due to scoliosis will be divided into PVB (n=16) and control (n=16) groups. Randomly selected patients of the PVB group are performed PVB with 0.2% ropivacaine on both sides. In contrast, PVB are not performed in the control group.

NCT ID: NCT04771689 Not yet recruiting - Post-operative Pain Clinical Trials

Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients

Start date: July 1, 2022
Phase: Phase 4
Study type: Interventional

A randomized clinical study evaluating the effect of buprenorphine/naloxone (bup/nx) sublingual film on postoperative pain management in opioid-tolerant patients.

NCT ID: NCT04768764 Not yet recruiting - Pain, Postoperative Clinical Trials

Comparison Of Femoral Block And Middle Adductor Canal Block In Patients With Knee Arthroplasty

Start date: April 16, 2021
Phase: Phase 4
Study type: Interventional

Femoral and adductor nerve blocks with ultrasonography(USG) guidance are used effectively and efficiently in post-operative pain management in lower extremity surgical procedures. However, the superiority of these two blocks to each other is still controversial. In this prospective, randomized, double-blind study, patients who underwent elective unilateral knee arthroplasty under spinal anesthesia, will be performed postoperative femoral block or middle adductor canal block with the guidance of USG.Patients who underwent spinal anesthesia and needed sedoanalgesia and who had to switch to general anesthesia will be excluded from the study. The patients will be divided into two groups by simple randomization. Since a total of 52 patients should be included in the study as a result of the power analysis (G-power 3.1); It is planned to take approximately 26 patients for each group.The anesthesiologist, who follows the pain control and mobilization after the block, will not know which study group the patient is in. The blocks will be performed behind the cover while the patient is under spinal anesthesia (Thus, the point of application of the block will not be noticed). In this way, the patient and the anesthesiologist who follows the parameters after the block will be blind to patient's arm. In the first group, 0.25% 20 ml of local anesthetic and middle adductor canal block, in the second group 0.25% 20 ml of local anesthetic and femoral nerve block will be applied We will compare these two blocks in terms of early mobilization, postoperative pain control, motor, and sensory block.

NCT ID: NCT04767399 Recruiting - Post Operative Pain Clinical Trials

Comparison of Postoperative Pain After Instrumentation in Different Visits With Different Single File Systems.

Start date: September 10, 2020
Phase: N/A
Study type: Interventional

Comparison of Postoperative Pain after Root Canal preparation, in Single and Multiple Visits, with Reciprocating and Rotary Single-File Systems: A Randomized Clinical Trial. Aim:1. Compare between the postoperative pain after root canal preparation, in single and multiple visits. 2. To assess the influence of reciprocating and rotary single-file systems instrumentation on post-operative pain.

NCT ID: NCT04765306 Completed - Pain, Postoperative Clinical Trials

Fascial Closure Technique After Gynecologic Laparoscopic Surgery and Postoperative Pain

Start date: March 5, 2021
Phase: N/A
Study type: Interventional

Our study aims to determine postoperative pain outcomes when comparing port site > 10 mm fascial closure with traditional direct closure versus use of laparoscopic fascial closure device in patients undergoing minimally invasive gynecologic surgery via laparoscopic or robotic techniques. Pain outcomes will be measured using the visual analog scale.

NCT ID: NCT04764916 Recruiting - Pain, Postoperative Clinical Trials

Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction

Start date: February 16, 2021
Phase: Phase 3
Study type: Interventional

This is a prospective, randomized study for adult patients presenting to the Carilion Clinic Institute of Orthopedics and Neurosurgery. Patients undergoing isolated ACL reconstruction will be eligible for inclusion. All patients will receive an adductor canal block (either with bupivacaine or Exparel. Patients will be given a pain diary for self-report of pill counts, pain scores, block duration, and pain control satisfaction). Pill counts and pain scores will also be taken by a team member at two and six-week post-operative visits. Primary outcomes include opioid requirements and pain scores.