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Pain, Postoperative clinical trials

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NCT ID: NCT05018104 Completed - Pain Clinical Trials

Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks

Start date: January 4, 2016
Phase:
Study type: Observational

Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care resources. People who are younger, female or have more pain before surgery are at higher risk of having rebound pain. Bone surgeries and upper limb surgeries also increase the chances of having rebound pain after surgery. Patients who have a tourniquet used during leg surgery often have worse pain after surgery compared to patients who get surgery without the use of a tourniquet. Things that may reduce the chances of getting rebound pain are the use of nerve block catheters, certain additives in nerve blocks and using multiple types of pain killers before the block wears off. Using nerve block catheters can be expensive, so a targeted approach of giving these catheters to patients who have the highest chances of getting rebound pain may be the best way to allocate resources and help patients. The aim of this study is to create and test a risk model for severe rebound pain after lower limb surgery where patients are getting a sciatic nerve block.

NCT ID: NCT05015907 Completed - Cancer Pediatric Clinical Trials

Ultrasound-guided Selective Supraclavicular Nerve Block for Postoperative Pain Control in Pediatric Patients.

Start date: October 22, 2021
Phase: N/A
Study type: Interventional

This prospective randomized controlled trial aims to investigate the effect of ultrasound-guided selective supraclavicular nerve block on pain control after Hickman catheter, chemoport, or Perm cath insertion in children.

NCT ID: NCT05012332 Completed - Postoperative Pain Clinical Trials

Local Anesthesia Spread After an Erector Spinae Plane Block.

Start date: September 17, 2021
Phase: N/A
Study type: Interventional

This a single-center prospective spread-evaluation study where the primary objective is to assess the spread of local anesthesia in an ESPB using magnetic resonance imaging (MRI). The investigators will include 10 healthy volunteers from the hospitals internal website. All volunteers will receive a one-sided Erector Spinae Plane (ESP) block. 30 min after the block sensitivity to cold and pinprick will be assessed before an MRI is performed after 60 min postblock. An radiology specialist will evaluate the MR images pertaining to the spread of the local anesthesia.

NCT ID: NCT05011084 Recruiting - Cryotherapy Effect Clinical Trials

Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

Cryotherapy has been used to enhance recovery after orthopaedic surgery. Many devices are available but few can guarantee a temperature regulation during a prolonged time and therefore have been criticized. The arrival of new advanced cryotherapy devices made it possible to test the effect of prolonged cooling on rehabilitation after arthroscopic orthopaedic procedures.

NCT ID: NCT05009771 Recruiting - Postoperative Pain Clinical Trials

Postoperative Pain Management of Caesarean Section

Start date: February 23, 2022
Phase:
Study type: Observational

Caesarean section is one of the most frequent surgeries causing severe postoperative pain. Poor management of acute pain can contribute to postoperative complications, late recovery and the development of chronic pain. Moreover, it had been demonstrated that the intensity of postpartum pain is associated with depression. It is imperative to find out appropriate methods of postpartum pain alleviation. Currently, a lot of analgesic drugs and methods have been developed and used in clinical practice, such as patient-controlled analgesia, extended-release analgesics and multimodal analgesia. This prospective cohort study is aimed to investigate the outcome of each postoperative analgesic method used in caesarean section.

NCT ID: NCT05009316 Completed - Coping Behavior Clinical Trials

Impact of Social Support and Coping Strategies on Post-Surgical Pain

POPQUEST
Start date: September 20, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the impact of social support and pain coping strategies in the development and evolution of post-surgical pain.

NCT ID: NCT05008614 Recruiting - Postoperative Pain Clinical Trials

Comparison of Continuous ESP Versus TEA After Thoracotomy

Start date: July 22, 2021
Phase: N/A
Study type: Interventional

This prospective, randomized, assessor-blinded study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided continuous erector spinae plane (ESP) block in patients undergoing thoracotomy. We hypothesize that US-guided ESP block is not inferior to thoracic epidural analgesia in terms of postoperative pain control in these patients.

NCT ID: NCT05008367 Completed - Postoperative Pain Clinical Trials

Effect of Dexamethasone as Analgesic Treatment After Total Knee Arthroplasty

Start date: September 14, 2018
Phase: Phase 4
Study type: Interventional

Effect of Dexamethasone as Analgesic Treatment After Total Knee Arthroplasty: Subgroup Analyses of The DEX-2-TKA Randomized Clinical Trial This explorative post-hoc analysis is a substudy of the DEX-2-TKA-trial (NCT03506789) investigating diffefferent subgroups of the patients included in the main trial.

NCT ID: NCT05005871 Completed - Pain, Postoperative Clinical Trials

Comparison of Quadratus Lumborum Intramuscular and Transmuscular in Postoperative Pain

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Acute pain is reported in approximately 80% of patients undergoing postoperative care for various types of surgical procedures in the United States. Another study reported patient postoperative pain intensity with 75% with severe pain in the first 1 to 2 postoperative days and 38% reporting moderate to severe pain at 14 postoperative days. Several modalities have been used as the standard for the management of pain postoperative C-sections. One of the postoperative analgesic modalities for SC is quadratus lumborum block (QLB). This technique has advantages in relieving postoperative pain after C-section because it is considered to be able to relieve visceral pain as well as somatic pain. The transmuscular QLB (QLBT) approach is one of the most frequently used. This technique was found to be effective with regard to the distribution of analgesics to the paravertebral spaces which is the hallmark of QLB. However, this technique was found to be difficult to perform. Difficulties were reported related to the position of the procedure i.e. lateral or sitting position.

NCT ID: NCT05005260 Completed - Pain, Postoperative Clinical Trials

Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty

Start date: October 14, 2021
Phase: Phase 4
Study type: Interventional

This study aims to assess analgesia efficacy between liposomal bupivacaine single injection interscalene blockade vs. continuous interscalene nerve block for patients undergoing primary total shoulder arthroplasty.