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Cryotherapy Effect clinical trials

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NCT ID: NCT06293209 Active, not recruiting - Ankle Fractures Clinical Trials

Effect of Cool Spray and Cold Packs in Reducing Preoperative Edema and Pain in Ankle Fractures in Ubonratchathani

3-armRCT
Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The use of evaporative coolants in the management of acute musculoskeletal injury has received increasing attention recently. However, its efficacy compared with conventional cryotherapy in treating injured human subjects remains unclear. The purpose of this study is to compare the efficacy of evaporative coolants with that of ice packs in the preoperative management of edema and pain in patients with an ankle fracture

NCT ID: NCT06223490 Recruiting - Cryotherapy Effect Clinical Trials

Effect of Cryolipolysis on Insulin Resistance

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Diabetes mellitus (DM) is a complex chronic illness associated with a state of high blood glucose level, or hyperglycemia, occurring from deficiencies in insulin secretion, action, or both. Diabetes mellitus is the name given to a wide spectrum group of disorders characterized by raised plasma glucose.Type 1 diabetes is characterized by an absolute insulin deficiency due to autoimmune destruction of insulin producing beta cells in the pancreas. most adults with diabetes have type 2, characterized by a relative insulin secretory defect, and target tissue resistance to the effects of insulin.

NCT ID: NCT06079437 Completed - Cryotherapy Effect Clinical Trials

The Effect of Brief Skin Cooling on Isometric Muscle Strength

Start date: April 10, 2023
Phase: N/A
Study type: Interventional

There is sympathetic innervation of the muscular spindle. The application of cold to the skin provides an increase in sympathetic activity. In rehabilitation practice, short-term local cold is applied to the skin to provide motor facilitation. The aim of this study was to examine whether short-term local cold application provides an increase in isometric contractile strength and, if so, whether this effect is related to muscle spindle activity.

NCT ID: NCT06037824 Completed - Knee Arthropathy Clinical Trials

Compressive Cryotherapy Versus Conventional Cryotherapy After Total Knee Arthroplasty

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

In the postoperative period of a total knee arthroplasty, subjects present limitations of articular amplitudes, swelling, pain and functional limitations. Functional rehabilitation is unanimously recommended, including the use of cryotherapy. However, there is no consensus regarding the methods of application of cryotherapy. Thus the objective of the study is to compare 2 cryotherapy techniques associated with a classic rehabilitation on the improvement of mobility, swelling, pain and functional parameters. The 2 cryotherapies were a compressive cryotherapy and a so-called classic cryotherapy by cold pack.

NCT ID: NCT06005727 Recruiting - Postoperative Pain Clinical Trials

Cryotherapy Post-haemorrhoidectomy (CYPHER) Randomized Controlled Trial

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Haemorrhoids is a common problem with an estimated prevalence of 5 to 36%. Surgery is indicated in patients with grade 3 to 4 piles and in patients whom conservative measures have failed. There have been several surgical techniques described such as the Milligan- Morgan, Ferguson haemorrhoidectomy, stapled and laser haemorrhoidectomy. However, most patients experience different degrees of postoperative pain which may cause anxiety and dissatisfaction. A relatively non-invasive and cost-effective technique targeting inflammation is cryotherapy which has been shown to decrease pain secondary to trauma, injury or disease. Cryotherapy has few deleterious side effects due to its non-pharmacologic nature and has become widespread in sports medicine to treat soft tissue damage. Therefore, we aim to evaluate the role of cryotherapy in improving postoperative pain and outcomes among patients who undergo haemorrhoidectomy.

NCT ID: NCT05896150 Recruiting - Thoracic Surgery Clinical Trials

Intercostal Cryoanalgesia for Acute Pain After VATS Lung Resection

CRYO-VATS
Start date: November 9, 2023
Phase: N/A
Study type: Interventional

Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the management of acute thoracic pain after VATS lung resection surgery.

NCT ID: NCT05884099 Recruiting - Lung Cancer Clinical Trials

Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection

CRYO-VATS-2
Start date: November 9, 2023
Phase: N/A
Study type: Interventional

Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the prevention of chronic thoracic pain after VATS lung resection surgery.

NCT ID: NCT05832970 Completed - Cryotherapy Effect Clinical Trials

Cooling Induces Motor Facilitation With Sympathetic Activation

Start date: April 3, 2023
Phase: N/A
Study type: Interventional

Cryotherapy has beneficial effects such as motor facilitation, increase isometric force generation, and reduce spasticity. It is known that the muscle spindle has sympathetic innervation. Muscle spindle sensitivity increase with sympathetic activity. This research has three hypotheses: First, short-term cold application to the skin increases sympathetic activity. Second, there is an increase in muscle spindle sensitivity with increased sympathetic activity. Third, the effect of short-term cold on muscle spindle sensitivity continues until the skin temperature returns to normal. The purpose of this research is to test these hypotheses.

NCT ID: NCT05692427 Recruiting - Cryotherapy Effect Clinical Trials

Evaluation of Cryotherapy in Granuloma Pyogenicum

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Surgical excision needs general anesthesia and might have complications due to anesthesia. Cryotherapy can be used in an outpatient setting and doesn't need general anesthesia. This study will evaluate if cryotherapy works in granuloma pyogenicum with the advancement of no general anesthesia.

NCT ID: NCT05600088 Recruiting - Clinical trials for Coronary Artery Disease

Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With NSTEMI or Unstable Angina

POLARSTAR
Start date: October 18, 2022
Phase: N/A
Study type: Interventional

The POLARSTAR study is an early safety and feasibility study to evaluate the performance and safety of the CryoTherapy System (CTS) for the treatment of coronary plaque lesions that are not obstructing blood flow but are at high-risk of rupture which would cause a major heart attack. The CTS is used to apply local freezing of the lesion using a balloon catheter, controlled by a console that regulates in- and outflow of a cooling agent into the catheter. The treatment is expected to stabilize the lesion, diminishing the risk of rupture. The study will enrol subjects with acute coronary disease who have suitable coronary lesions. Subjects will be followed for 1 year after the CTS treatment. Baseline identification of lesions will be done using Coronary CT-angiography (CCTA), which will be repeated at 3 and 9 months after procedure.