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Obesity clinical trials

View clinical trials related to Obesity.

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NCT ID: NCT03845868 Recruiting - Obesity Clinical Trials

Tongji-Ezhou Study

TJEZ
Start date: April 16, 2013
Phase:
Study type: Observational

Tongji-Ezhou study (TJEZ) is a prospective cohort study launched at 2013 in EZhou city, Hubei province, with the goal of recruiting and assessing 10,000 individuals and then following them for at least 2 decades. In addition, blood samples would be collected every 3-5 years among 6000 of them to investigate the nutritional biomarkers and potential determinants of chronic diseases such as obesity, type 2 diabetes, metabolic syndrome, and cardiovascular disease.

NCT ID: NCT03842475 Recruiting - Obesity Clinical Trials

Who Will Benefit From Bariatric Surgery for Diabetes?

Start date: October 1, 2018
Phase:
Study type: Observational

A study investigating the influence of fat distribution, genetic susceptibility markers for type 2 diabetes (T2DM) and fat distribution, epigenetic and transcriptomic changes and gut hormone responses to a mixed meal on diabetes remission following bariatric surgery.

NCT ID: NCT03841682 Recruiting - Obesity Clinical Trials

Engaging Self-regulation Targets to Improve Mood and Weight and Understand Mechanism in Depressed and Obese Adults

Start date: February 12, 2019
Phase: N/A
Study type: Interventional

Multimorbidity (i.e., the coexistence of 2 or more chronic conditions in an individual) is increasingly recognized as a pressing public health problem. Effective interventions targeting coexisting depression and obesity are critical given the high prevalence and worsened outcomes for patients with both conditions. ENGAGE-2 is a pilot randomized controlled trial (RCT). The objective is to investigate the outcomes and mechanisms of an integrated depression and obesity intervention that combines collaborative stepped depression treatment and evidence-based behavioral weight loss treatment. The Integrated Coaching for Better Mood and Weight-2 (I-CARE2) intervention synergistically integrates 2 proven national programs: the Program to Encourage Active and Rewarding Lives (PEARLS) for depression care and the Group Lifestyle Balance (GLB) program for weight loss and cardiometabolic risk reduction. In Phase 1 of the ENGAGE project, investigators developed a new protocol to quantify activation and connectivity of the Affective, Cognitive Control, and Default Mode brain circuits from functional magnetic resonance imaging (fMRI) among 108 depressed obese patients. Investigators implement the same fMRI protocol in this second phase of the project to examine the mechanistic role of these brain circuits as potential neural targets in treatment engagement and response in the I-CARE2 intervention. A new sample of 105 depressed obese patients are randomized in a 2:1 ratio to receive the I-CARE2 intervention (n=70) or usual care (n=35). Study assessments occur at 0 (baseline), 2 and 6 months. Investigators hypothesize that 1 or more of the neural targets under study will moderate (baseline state) and/or mediate (change at follow-up) the effect of the I-CARE2 intervention versus usual care on health behaviors (problem-solving ability, dietary intakes, physical activity) and clinical outcomes (weight loss, depression, anxiety).

NCT ID: NCT03836391 Recruiting - Obesity Clinical Trials

Precision Public Health: Enhancing Connections to Develop Just-in-Time Adaptive Intervention Strategies

Nudge
Start date: February 8, 2019
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to examine the effects of different types of just-in-time intervention messages on daily meeting dietary, activity, and weighing goals in a sample of young adults participating in a mobile-based weight loss program.

NCT ID: NCT03826212 Recruiting - Obesity Clinical Trials

Efficacy and Safety of Soybean Germ Extract on Decrease of Body Fat

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This study was conducted to investigate the effects of daily supplementation of Soybean germ extract on decrease of body fat

NCT ID: NCT03826173 Recruiting - Obesity Clinical Trials

Positive Psychology for Physical Activity Promotion

PPPA
Start date: October 26, 2018
Phase: N/A
Study type: Interventional

This study is for physically inactive adults. Participants will be enrolled in the Positive Psychology and Physical Activity intervention designed to help them overcome barriers to physical activity, based on the principals of positive psychology. This will involve six weekly one-hour group-based sessions at a local YMCA with a trained group leader. In addition to the in-person sessions, there will be text messages sent to participants about physical activity that include positive psychology content.

NCT ID: NCT03821961 Recruiting - Obesity Clinical Trials

18F-FDOPA PET/CT Imaging in Patients Undergoing Metabolic Surgery

Start date: September 3, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to compare the endocrine function of pancreas between pre and post metabolic surgery in patients with type 2 diabetes or prediabetes. The study will examine the endocrine function of pancreas using 18F-FDOPA PET/CT imaging and various biochemical laboratory tests

NCT ID: NCT03821818 Recruiting - Obesity Clinical Trials

Food Allergen Eliminations and Combined Protocols for Obesity Reduction: a Preliminary Comparison Study

Start date: March 5, 2018
Phase:
Study type: Observational

Screened subjects will be tested for hidden food allergies. Subjects will eliminate all food that showed leukocyte reactions for 90-days. Subjects will then also be invited to use the Willis Exercise protocol. Body composition testing and Body Mass Index calculation will be accomplished at enrollment and after completion of the 90-day study.

NCT ID: NCT03816462 Recruiting - Obesity Clinical Trials

ReNEW Clinic Cohort Study

ReNEW
Start date: January 2015
Phase:
Study type: Observational

This is an ongoing, prospective cohort study of children and young adults who are evaluated in the Reversing the Negative Effects of Weight on the Heart (ReNEW) Clinic at Johns Hopkins University. Demographic and clinical data of patients who agree to participate are obtained via chart review and entered into a longitudinal clinic registry.

NCT ID: NCT03815253 Recruiting - Central Obesity Clinical Trials

Electro-acupuncture for Central Obesity

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

In this study, a 8-week, single blinded, randomized controlled clinical trial will be conducted to examine the efficacy and safety of body acupuncture in the treatment of central obesity in Hong Kong.