Clinical Trials Logo

Obesity clinical trials

View clinical trials related to Obesity.

Filter by:
  • Enrolling by invitation  
  • Page 1 ·  Next »

NCT ID: NCT03225196 Enrolling by invitation - Obesity Clinical Trials

Extracellular RNAs in Relation to Cardiometabolic Risk

Start date: August 18, 2017
Phase: N/A
Study type: Observational

Background: Extracellular RNAs (exRNAs) send genetic data from cell to cell. This is how they affect the way cells communicate with each other. There are many types of exRNA, and they each serve different roles. But they have also been linked to some diseases. Researchers want to measure exRNAs to see how they relate to certain traits over time. They will use blood samples that were taken as part of the Framingham Heart Study (FHS). Objectives: To identify cross-sectional associations of exRNAs with age, sex, and cardiometabolic risk factors. Eligibility: People ages 30-70 who had blood taken as part of the FHS Third Generation cohort. Design: Researchers will study samples that have already been collected in the FHS. There will be no active participant contact for this project, only use of data that are collected as part of planned follow up from other studies. As part of the FHS, participants gave blood samples. They gave permission for the blood to be used for research. The exRNAs from the blood samples will be studied to see how they relate to certain traits. These include age, sex, and body mass index. The exRNAs will also be studied for their usefulness as biomarkers of risk for subclinical atherosclerotic cardiovascular disease. No study participants will be contacted for this study.

NCT ID: NCT03215485 Enrolling by invitation - Clinical trials for Childhood Obesity Prevention

WAVE~Ripples for Change: Obesity Prevention in Active Youth

Start date: August 2014
Phase: N/A
Study type: Interventional

Intervention targets youth ages 14 - 19 participating in soccer teams. The intervention group will be given face to face nutrition lessons and have access to an online immersive learning environment. The comparison group will not. The project will test if the immersive learning environment is effective in preventing unhealthy weight gain.

NCT ID: NCT03200535 Enrolling by invitation - Obesity Clinical Trials

Comparison of Outreach Methods to Encourage Enrollment in Diabetes Prevention and Weight Management Programs

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

Individuals with prediabetes are at increased risk for developing diabetes. Higher hemoglobin A1c's (6.1-6.4%) are associated with a high risk of developing diabetes. It is known that programs such weight management classes and one-on-one counseling with registered dieticians can lead to weight loss and decrease the risk of diabetes. However, engagement of Kaiser Permanente Colorado members in these activities is low. The purpose of this study is to determine which of three outreach methods is most effective in increasing engagement in these activities.

NCT ID: NCT03197363 Enrolling by invitation - Obesity Clinical Trials

Białystok PLUS - Polish Longitudinal University Study

Bialystok+
Start date: July 2017
Phase: N/A
Study type: Observational

The main goal of the study is to provide a unique multidimensional picture of the health of the population with simultaneous optimal standards of sampling, processing and storing of data and biomaterial that will allow discovering novel mechanisms in the development and progression of common civilization diseases. In the effect it will improve prevention, diagnosis and treatment.

NCT ID: NCT03191591 Enrolling by invitation - Physical Activity Clinical Trials

The First 1,000 Days Program: Maternal-Child Obesity Prevention in Early Life

Start date: August 9, 2016
Phase: N/A
Study type: Interventional

The First 1000 Days (conception to age 2) is a crucial period for the development and prevention of obesity and its adverse consequences in mother-child pairs and their families. The overall aim of the First 1000 Days program is to work across early-life systems to prevent obesity, promote healthy routines and behaviors, address social determinants of health, and reduce health disparities among vulnerable children and families at the MGH Chelsea and Revere HealthCare Centers, and DotHouse Health. The study aims to simultaneously implement and evaluate an obesity prevention program across early life systems to reduce the prevalence of obesity risk factors within racial/ethnic minority families, close the gap in maternal-child health disparities, and assess and address social determinants of health.

NCT ID: NCT03063606 Enrolling by invitation - Obesity Clinical Trials

Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Specialist Treatment

Start date: June 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This study will test the effectiveness of cognitive-behavioral therapy as a specialist treatment for binge eating disorder (BED) in patients with obesity. This is a controlled test of whether, amongst non-responders to acute treatments, cognitive-behavioral therapy augments on-going blinded pharmacotherapy (either naltrexone/bupropion or placebo), compared with no additional behavioral treatment .

NCT ID: NCT03047005 Enrolling by invitation - Obesity Clinical Trials

Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy

Start date: June 2017
Phase: Phase 2/Phase 3
Study type: Interventional

This study will test the effectiveness and relative efficacy of naltrexone/bupropion medication as a maintenance therapy for the treatment of binge eating disorder (BED) in patients with obesity. This is a controlled test of whether, amongst responders to acute treatments, naltrexone/bupropion medication results in superior maintenance and longer-term outcomes compared with placebo.

NCT ID: NCT03029936 Enrolling by invitation - Obesity Clinical Trials

Obesity-asthma Endophenotype and Diaphragm Mobility in Adolescence

Start date: July 1, 2016
Phase: N/A
Study type: Observational

Obesity and asthma share changes that may begin in the fetal development phase. The endophenotype obesity-asthma presents as main characteristic a pattern of inflammatory response different from the habitual Th2 profile of cytokines. In these obese patients, possible changes in the diaphragm muscle can directly influence the dynamics of pulmonary ventilation significantly. Due to the importance of the diaphragm in pulmonary ventilation, this study will be performed to verify possible alteration in the excursion and diaphragmatic thickness of adolescents with endophenotype obesity-asthma. In parallel, the possible underlying etiopathogenic substrate of this endophenotype will be explored through the dosing of muscle enzymes and inflammatory cytokines and obesity hormones.

NCT ID: NCT03024879 Enrolling by invitation - Healthy Clinical Trials

The Effect of Motilin on the Frequency and Amount of Food Intake

Start date: March 2014
Phase: Phase 4
Study type: Interventional

In this study, the investigators aimed at evaluating the role of motilin in the regulation of food intake. Motilin, a gastrointestinal hormone, is a hunger signal in healthy volunteers and is significantly increased in obese patients. Its role in food intake regulation might contribute to the pathogenesis of obesity.

NCT ID: NCT03012126 Enrolling by invitation - Clinical trials for Overweight and Obesity

Clinical & Community Approaches to Weight Management

CORD 2
Start date: December 2016
Phase: N/A
Study type: Interventional

This project seeks to build on innovative strategies to optimize the care of low-income children with a BMI ≥ 85th percentile. To accomplish this goal, investigators will implement a new clinical-community intervention, theoretically grounded in the Integrated Clinical and Community Systems of Care Model, to address obesity through optimized screening and management known to be effective, e-Referrals, Healthy Weight Clinics, and the YMCA's Healthy Weight and Your Child weight management program (originally known as MEND). The study will examine outcomes for children that matter most to a broad group of stakeholders including parents, clinicians, and public health practitioners as well as inform the care of >7 million children with obesity covered by the Children's Health Insurance Program or Medicaid.