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Obesity clinical trials

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NCT ID: NCT03558100 Enrolling by invitation - Obesity Clinical Trials

Reducing Fall Risks for Adults With Obesity

ObesityFalls
Start date: September 1, 2014
Phase: N/A
Study type: Interventional

The objective of the clinical study was to examine if practice could improve walking patterns associated with fall risks before patients with obesity underwent weight loss surgery. We hypothesized that patients would show improvements in their walking after completing the intervention. For the intervention, patients walked under five conditions: on flat ground at the beginning of the study, crossing three obstacle heights, and on flat ground at the end of the study for a total of 25 times.

NCT ID: NCT03542864 Enrolling by invitation - Obesity Clinical Trials

Medical Supervised Duodenal-Enteral Feeding Treatment

Start date: August 3, 2017
Phase: N/A
Study type: Interventional

Medical Supervised Duodenal-Enteral Feeding for Overweight, Obesity and Increased Body Fat Percentage Treatment based on an intervention procedure performed by a Licensed Nutritionist Doctor for weight loss and loss of fat percentage in patients who need it.

NCT ID: NCT03534232 Enrolling by invitation - Obesity Clinical Trials

Insulin-Related Biomarkers and Exposures and Risk of Pancreatic, Lung, and Other Cancers

Start date: June 20, 2018
Phase:
Study type: Observational

Background: Diabetes has been associated with many cancers including liver, pancreas, endometrial, colorectal, breast and bladder cancer. Excess body fat has also been linked to cancer. One reason for this might be resistance to insulin. Researchers want to look for links between insulin, diabetes, and certain cancers. They want to study data that has already been collected. Objectives: To study links between insulin, diabetes, and cancers. To study how the links might differ by gender, race, and other factors. Eligibility: People who already participated in 1 of 8 cardiovascular disease studies Design: Researchers will study data that has already been collected. There will be no active participants. Participants gave permission to share their data. The data contain no personally identifying information. Researchers will look at biomarkers like diet, medicines, and tobacco use. They will do statistical analysis of the data

NCT ID: NCT03528317 Enrolling by invitation - Obesity Clinical Trials

Alternate Day Fasting Combined With a High Protein Background Diet

Start date: May 30, 2018
Phase: N/A
Study type: Interventional

The aims of this study are as follows: AIM 1: To examine the weight loss and weight maintenance efficacy of an alternate day fasting-high protein (ADF-HP) diet; AIM 2: To examine the effects of an ADF-HP diet on metabolic disease risk factors (plasma lipids, fasting glucose, fasting insulin, insulin resistance).

NCT ID: NCT03472157 Enrolling by invitation - Obesity Clinical Trials

A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients

NASHSURG
Start date: July 2018
Phase: N/A
Study type: Interventional

The aim of the study is to demonstrate the superiority of bariatric surgery on the disappearance of NASH without worsening of fibrosis in comparison to medical standard treatment in obese patients (35 kg/m² > BMI ≥ 30 kg/m²) with NASH complicated of advanced fibrosis (F3 and F4 fibrosis grade according to Brunt score).

NCT ID: NCT03460834 Enrolling by invitation - Obesity Clinical Trials

Asthma and Obesity: Observational

Start date: May 1, 2016
Phase: N/A
Study type: Observational

Obesity is associated with poor asthma control and greater healthcare utilization and costs. In this study the researchers will examine the biologic and behavioral interrelationships between these conditions and their impact on outcomes. Towards this end, the researchers will conduct an observational prospective cohort study of 400 obese asthmatic patients treated at institutions in New York City and Denver, and develop and pilot test educational and counseling modules that take an integrated approach to asthma and obesity self-management support.

NCT ID: NCT03450655 Enrolling by invitation - Visceral Obesity Clinical Trials

Cardio Training of Older Adults With Central Obesity

Start date: February 9, 2018
Phase: N/A
Study type: Interventional

Given the increasing prevalence of obesity, there is an urgent need to find better strategies to promote physical activity in the community. The present study will invite 70-year-olds with central (abdominal) obesity to participate in a 10-week aerobic exercise program. Participants will be randomly assigned to one of two equally large groups. The first group will complete the exercise program in instructor-led groups. The second group will complete the program at home with the help of an on-line video.

NCT ID: NCT03407833 Enrolling by invitation - Obesity Clinical Trials

Physiologic and Functional Adaptations of Insulin Sensitive Tissues

Start date: February 13, 2018
Phase: N/A
Study type: Observational

The long-term goal is to understand the mechanisms of intestinal nutrient sensing and signal relays to insulin sensitive tissues (adipose, skeletal muscle, liver) in humans. The investigators hypothesize that human tissue biopsies (from obese surgery and non-surgery subjects as well as lean controls) can be used to understand the molecular mechanisms underlying intestinal nutrient sensing and signal relay in humans. The investigator will obtain tissue specimens from obese patients during scheduled upper endoscopies, colonoscopies and scheduled metabolic and bariatric surgeries. The investigator will obtain tissue specimens from lean patients during scheduled endoscopies and colonoscopies. A blood sample (4mL) will be obtained concurrent with these procedures. From metabolic and bariatric surgery subjects blood and tissues (liver, adipose, small intestine, omentum, skeletal muscle) will be collected at the time of surgery. Stool will be obtained preoperatively and at various time points after surgery.

NCT ID: NCT03396302 Enrolling by invitation - Obesity Clinical Trials

Lifestyle On-line Intervention in Patients With Obesity and Hypertension

Start date: January 22, 2018
Phase: N/A
Study type: Interventional

This study aims to describe a totally self-applied online program to promote healthy lifestyles (nutritional education and exercise practice) for obese participants with hypertension. Participants will be recruited from users of a hypertension unit of a public hospital and will be randomized into two groups: experimental group and control group (treatment as usual). The experimental program (3 months) will be composed by 8 modules aimed for promoting healthy eating habits and increase physical activity. Assessment will include: body composition (BMI), blood pressure, glucose metabolism variables, and physical activity level (measured with accelerometers). Design: Randomized Controlled Trial.

NCT ID: NCT03378765 Enrolling by invitation - Obesity Clinical Trials

Gut Microbiota, Short Chain Fatty Acids, and Adiposity Across The Epidemiological Transition

Start date: January 2, 2018
Phase: N/A
Study type: Observational

The objective of this study is to define associations between gut microbiota, SCFAs and obesity in populations spanning the epidemiologic transition, and explore mechanisms by which these factors may independently and collectively influence the development of obesity. The central hypothesis of this study is that the composition of gut microbiota drives SCFA production which in turn influences obesity risk at the population-level.