Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Heart Disease Death

Nonfatal Myocardial Infarction Clinical Trial

Official title:
Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Heart Disease Death - Nested Case Control Analyses in a Cohort of Patients With Acute Serious Coronary Heart Disease

Status Completed

Clinical Trial Summary

The purpose of this study is to estimate the risk of myocardial infarction (MI)/coronary death associated with use of monotherapy low dose ASA (single antiplatelet) as well as concomitant use of monotherapy low dose ASA and proton pump inhibitors (PPIs) in patients with serious coronary heart disease using two UK primary care databases.

Clinical Trial Description

Number of Anticipated Subjects: In case-control analysis: 10.000-15.000 participants ;

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01360073
Study type	Observational
Source	AstraZeneca
Contact
Status	Completed
Phase	N/A
Start date	July 2011
Completion date	December 2011

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See also
	Status	Clinical Trial	Phase
	Completed	`NCT01859897` - A Prospective Multicenter Study to Evaluate Usefulness of Cardio-Ankle Vascular Index in Japan
	Completed	`NCT01360047` - Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Death	N/A