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Heart Diseases clinical trials

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NCT ID: NCT03953924 Completed - Depression Clinical Trials

TTM-based Intervention and MI in CHD Patients

Start date: August 1, 2015
Phase: N/A
Study type: Interventional

In the middle of this century, coronary heart disease (CHD) is the most common cause of death in the United States. Chinese health service survey showed that about 1000,0000 ~ 320,000 people were suffering from CHD in the mainland of China in 2008. The high mortality and morbidity of CHD will aggravate the psychological burden of patients, such as depression. Depression is the most psychological problem in CHD patients. The incidence of depression in Chinese population was in the range of 4%~6%, while it was as high as 14%~17% in patients with CHD. Depression not only affects the patients' illness, but also reducing their quality of life, the compliance of drugs and lifestyle. In addition, depression is a major risk factor for the mortality and morbidity of cardiovascular disease. Therefore, it's urgently needed to screen and treat the depression of patients with CHD. At present, the treatment of depression in patients with CHD mainly includes antidepressant, cognitive behavioral therapy´╝î psychological counseling, knowledge education, relaxation therapy and so on. However, the medicine would yield side - effect. Furthermore, the content of psychological interventions are not systematic and dynamic. Moreover, patients' depressive level varies in different periods, the traditional psychological intervention just focused on the ultimate psychological benefits, and cannot analyze some factors and staged results in the process of psycho-behavioral change. Thus, an dynamic and effective intervention to alleviate depression in patients with CHD is imperative.

NCT ID: NCT03949829 Enrolling by invitation - Clinical trials for Cardiovascular Diseases

The CoPenHagen PREeClampsia and cardIOvascUlar diSease Trial

CPH-PRECIOUS
Start date: May 20, 2019
Phase:
Study type: Observational [Patient Registry]

Women with a history of preeclampsia (PE) have increased risk of hypertension and cardiovascular disease (CVD) later in life. Thus, PE is acknowledged as an independent risk factor for CVD, which is the number one cause of death in women in the western part of the world. Objective: The purpose of this study is to investigate 1) the prevalence of CVD after PE, 2) which women have the highest risk of developing CVD, 3) when early stages of CVD can be detected in women with previous PE and 4) how CVD progress over time. Methods: 1000 women with previous PE between the age of 35-55 years will be invited to participate in a follow-up study consisting of anthropometric measurements, blood pressure measurement, urine- and blood samples, cardiac CT-scan and questionnaires. Coronary atherosclerosis will be evaluated using CT imaging.The women will be compared with women with a formerly uncomplicated pregnancy, Summary: The study will provide new important information to guide future clinical follow-up, and potentially prevent disease and early death in a large group of women with a history of PE.

NCT ID: NCT03947021 Recruiting - Heart Diseases Clinical Trials

Developing Methods for Reconstructing Electrical Heart Activity

Start date: January 2012
Phase: N/A
Study type: Interventional

Non-invasive reconstruction of electrical heart activity can yield important scientific and clinical insights in cardiac rhythm disorders. In this study, The investigators aim at developing methods for reconstructing electrical heart activity non-invasively, and to use these methods to investigate cardiac rhythm disorders to answer clinical and scientific questions.

NCT ID: NCT03946956 Completed - Vascular Diseases Clinical Trials

Fighting Social Inequality in Cardiovascular Health I

FISICH-I
Start date: August 1, 2017
Phase: N/A
Study type: Interventional

This study attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease (CVD) among people with low social status

NCT ID: NCT03946462 Not yet recruiting - Acute Kidney Injury Clinical Trials

Nitric Oxide During CPB to Reduce AKI in Neonates

Start date: July 2019
Phase: Phase 1
Study type: Interventional

This is a prospective, randomized, double-blind, placebo-controlled pilot study to investigate whether supplemental Nitric Oxide (NO) gas delivered during cardiac surgery with cardiopulmonary bypass (CPB) reduces the incidence and impact of acute kidney injury (AKI) in neonates undergoing surgery for congenital heart disease (CHD), when compared to placebo gas

NCT ID: NCT03946410 Recruiting - Vascular Diseases Clinical Trials

Danish Cardiovascular Screening Trial II

DANCAVAS-II
Start date: August 1, 2017
Phase: N/A
Study type: Interventional

This study attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease (CVD) among people with low social status.

NCT ID: NCT03945968 Not yet recruiting - Stroke Clinical Trials

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.

STOP RISK
Start date: July 1, 2019
Phase:
Study type: Observational

Study is conducted to assess the prevalence and structure of comorbidity among patients undergoing abdominal surgery and produce the stratification of the risk of postoperative complications by identifying independent predictors for its development.

NCT ID: NCT03944837 Recruiting - Clinical trials for Congenital Heart Disease

Acute Maternal Hyperoxygenation in CHD

Start date: April 26, 2019
Phase: N/A
Study type: Interventional

Congenital heart disease (CHD) is predominantly detected before birth. Using echocardiography and MRI, this study will determine whether acute exposure to maternal hyperoxygenation (MH) leads to measurable increases in fetal cerebral oxygenation from baseline in fetuses with CHD. The study aims to determine whether MH could be used as a chronic in-utero treatment strategy to promote brain growth/maturation to birth and to improve postnatal neurodevelopmental outcomes, and identify the types of CHD most likely to benefit from chronic MH.

NCT ID: NCT03941275 Not yet recruiting - Heart Diseases Clinical Trials

SelectSecure 3830 Lead Imaging

Start date: June 1, 2019
Phase:
Study type: Observational

This study is designed to collect high-quality shoulder and intracardiac bi-plane fluoroscopic images during two standard arm motions on patients implanted with a market released SelectSecure 3830 lead for the purposes of developing a fracture reliability model.

NCT ID: NCT03940066 Not yet recruiting - Atrial Fibrillation Clinical Trials

Evaluation of Ambulatory Monitoring of Patients After High-risk Acute Coronary Syndrome Using Two Different Systems: Biomonitor-2 and Kardia Mobile

Monitor- ACS
Start date: June 1, 2019
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the efficacy of monitoring after discharge of patients with high-risk acute coronary syndrome.