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Heart Diseases clinical trials

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NCT ID: NCT03801837 Not yet recruiting - Heart Diseases Clinical Trials

Effect of Macadamia Nut on Cardiometabolic Risk Factors

Start date: March 2019
Phase: N/A
Study type: Interventional

This research study will test the effects of macadamia nuts on adiposity, and traditional and emergent risk factors of cardiometabolic disease in adult men and women

NCT ID: NCT03799133 Recruiting - Clinical trials for Valvular Heart Disease

Safety and Efficacy of the Gastric Reactance (XL) in Patients Post-operated of Elective Cardiac Surgery

Start date: September 26, 2018
Phase: N/A
Study type: Interventional

Evaluate the safety and effectiveness of the XL trend measured by Florence (Critical Perfusion Inc, Palo Alto, California) in the prediction of morbimortality of Mexican patients post-operated of elective cardiovascular surgery. Hypothesis: 1. The gastric reactance measurement (XL) correlates with the morbimortality (postoperatory shock, excessive bleeding, vasoplegic syndrome and death) and with the risk predictors (APACHE II, STS, SOFA, and EUROSCORE II) with patients post-operated of elective cardiac surgery. 2. It is possible to identify the cut-off point of the values of the gastric reactance (XL) as a predictive tool of morbimortality in patients post-operated of elective cardiac surgery. 3. The gastric reactance (XL) is a safe measurement to patients undergoing cardiac surgery.

NCT ID: NCT03797820 Recruiting - Clinical trials for Valvular Heart Disease

Multicenter Registry Study of Aortic Valve Stenosis in Zhejiang Elderly(Mrs AVS)

Start date: October 1, 2018
Study type: Observational [Patient Registry]

Aortic valve stenosis (AVS) is becoming more and more frequent with the aging, which has brought a heavy burden to the world. However, the prevalence and prognosis of valvular heart disease are not so clear, especially in the developing countries such as China etc. Because of the slow and progressive nature of AVS, symptoms might not be too severe to be diagnosed on time. Our retrospective survey (Int J Cardiol. 2016 Nov 25) indicated that severe aortic valve stenosis are very common in China. Hence, we design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective ,treatments and prognosis of Chinese elderly patients with aortic valve stenosis.

NCT ID: NCT03797339 Recruiting - Clinical trials for Coronary Heart Disease

Multi-omics Study of Clinical Endpoints in CHD

Start date: July 1, 2017
Study type: Observational

This study aimed to explore underlying mechanisms of individual differences in drugs for coronary heart disease treatment and its association with adverse consequences. It will enroll approximately 4000 coronal heart disease patients aged between 18 and 80 years in mainland China and follow-up for at least 1 years. Questionnaires, anthropometric measures, laboratory tests, and biomaterials will be collected . The principal clinical outcomes of the study consist of ischemia attack , cardiac death, renal injury,and myotoxic activity.

NCT ID: NCT03796741 Completed - Clinical trials for Chronic Ischemic Heart Disease

STable Coronary Artery Diseases RegisTry

Start date: March 17, 2016
Study type: Observational

Observational, prospective multicentric, national study, evaluating the diagnostic and therapeutic pathways of patient with cronic coronary artery disease followed in Italian cardiology centers.

NCT ID: NCT03795714 Recruiting - Clinical trials for Ischemic Heart Disease

Association Between IVUS Parameters and Invasive Physiologic Indices

Start date: November 17, 2017
Study type: Observational

1. to evaluate diagnostic accuracy and performance of IVUS-derived quantitative parameters to predict functional significance of stenosis defined using all the available physiologic indices. 2. to explores the association between IVUS-derived plaque characteristics and invasive physiologic indices.

NCT ID: NCT03794531 Enrolling by invitation - Obesity Clinical Trials

Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico

Start date: December 17, 2018
Study type: Observational

The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing cardiovascular-related disparities in Puerto Rico. To this end, investigators will establish 'PROSPECT: Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic disease Trends', an island-wide, longitudinal population cohort of 2,000 adults (30-75 years) in PR recruited with a multi-frame sampling of probabilistic plus community approaches, and assessed in a network of several partner clinics across the island. The study will collect comprehensive data on multiple psychosocial, dietary, and food-related factors, CVD biological markers, and medical record data, with follow-up at 2-years, and will assess variations by urban-rural area and by timing before-after Maria.

NCT ID: NCT03791788 Recruiting - Clinical trials for Ischemic Heart Disease

Multicenter Registry for Angiography-Derived Quantitative Flow Ratio

Start date: November 30, 2018
Study type: Observational

1. to investigate the feasibility and diagnostic performance of contrast quantitative flow ratio (QFR) for identifying the functional significance of intermediate degree stenotic lesions in all-comer patients with coronary artery disease (CAD) including presentation of acute myocardial infarction (AMI) with non-culprit lesion. 2. to compare the changes of contrast QFR and fractional flow reserve (FFR) according to severity of percent diameter stenosis (%DS)

NCT ID: NCT03787082 Not yet recruiting - Clinical trials for Pulmonary Hypertension

Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension

Start date: February 2019
Phase: Phase 1
Study type: Interventional

This is an open-label, single-center study to examine distinguishing features of the structure and function of the oral and gut microbiome in volunteers with PH in the breakdown of oral nitrate and effect on hemodynamics.

NCT ID: NCT03786965 Recruiting - Clinical trials for Ischemic Heart Disease

Evaluating of Role of Myeloperoxidase in Prediction of Outcomes of Cardiac Surgery Procedures.

Start date: December 20, 2018
Phase: N/A
Study type: Interventional

The main objection is to investigate molecular biology of myocardial damage during cardiac surgery procedures.