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HIV Infections clinical trials

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NCT ID: NCT00549523 Completed - HIV Infections Clinical Trials

A Controlled Study of the Safety and Efficacy of Lessertia Frutescens in HIV-infected South African Adults

Start date: April 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The study is a 2-stage, double-blind, randomized, placebo-controlled study in which fifty-six HIV-positive subjects will be randomized into the first stage. Interim analysis to determine continuation to stage 2 will be performed to determine continuation after 8 subjects per arm have completed a 24-week dosing regimen. Primary objectives are to determine the safety of Lessertia frutescens when used by HIV-1 infected adults with early disease, and to document the impact of Lessertia frutescens on markers of HIV disease progression. Secondary objective is to determine the effect of Lessertia frutescens on quality of life in HIV-infected adults and length of infection.

NCT ID: NCT00549367 Completed - HIV Infections Clinical Trials

The Role of Diet Education and Nutritional Counselling in the Ongoing Care of People Living With HIV in Thailand

TACH001
Start date: November 2007
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of nutrition education and dietary counselling to improve the nutritional status, well-being and quality of life of people living with HIV/AIDS (PLWHA) attending an HIV treatment facility in Bangkok Thailand.

NCT ID: NCT00549198 Completed - HIV Infection Clinical Trials

KIVEXA Vs TRUVADA, Both Administered With Efavirenz, In ART-Naive Subjects

ASSERT
Start date: June 2007
Phase: Phase 4
Study type: Interventional

Recently, the fixed-dose combinations (FDC) KIVEXA™ (abacavir/lamivudine) and TRUVADA (tenofovir disoproxil fumarate/emtricitabine) have facilitated the usage of once-daily regimens. However data from head-to-head randomized trials comparing these two FDCs as part of an initial regimen are not available at present. The long-term toxicity profiles of these regimens are of particular importance, as treatment of HIV is currently life-long and therefore, minimizing long-term toxicity and maximizing adherence and duration of regimen maintenance are critical therapy objectives. The primary endpoint is estimated glomerular filtration rate (GFR), as measured by the modified diet in renal disease (MDRD) equation, a validated estimate of renal function.

NCT ID: NCT00548275 Completed - HIV Infections Clinical Trials

Reducing Sex-Related HIV Risk Behaviors in Patients Receiving Treatment for Opioid Dependence

Project RED
Start date: July 2006
Phase: Phase 2
Study type: Interventional

The major goal is to determine in patients entering buprenorphine treatment, the prevalence of specific sex-related HIV risk behaviors, their physician's screening of these behaviors and to evaluate the impact of risk reduction counseling.

NCT ID: NCT00548041 Completed - HIV Infections Clinical Trials

Rapid HIV Testing Program in the Emergency Department

Start date: April 2007
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the feasibility of a rapid HIV testing program in the Temple University Hospital(TUH)Emergency Department. We hypothesize that a rapid HIV testing program in the TUH Emergency Department is feasible. Patients presenting to the Adult TUH Emergency Department with certain conditions will be offered rapid HIV testing. Testing will be performed by oral swab using the OraQuick Advance test. Patients will receive post-test counseling.

NCT ID: NCT00546689 Completed - HIV Infections Clinical Trials

Correlation Between Intestinal Parasites and Serum Level of Eosinophils and IgE in Individuals With HIV or AIDS

Start date: March 2007
Phase: N/A
Study type: Observational

Correlation between intestinal parasites and serum level of eosinophils and IgE in individuals with HIV or aids attended at clinical hospital of the Botucatu Medical School-UNESP

NCT ID: NCT00545987 Completed - HIV Infections Clinical Trials

Study of a Potential Preventive Vaccine Against HIV in Healthy Volunteers

ADVAX-EP
Start date: September 2007
Phase: Phase 1
Study type: Interventional

This study will test the safety of a HIV DNA vaccine after it is injected into your muscle using an electroporation device (TriGrid™ Delivery System made by Ichor Medical Systems), and will test the ability of the vaccine to help your body make antibodies and T-Cells. In this study, we would like to learn about the effects that electroporation of the HIV DNA has on you and your immune system.

NCT ID: NCT00545623 Completed - HIV Infections Clinical Trials

Acupuncture and Relaxation Response for GI Symptoms and HIV Medication Adherence

Start date: April 2007
Phase: Phase 2
Study type: Interventional

The aims of the study are to investigate individual, combined and added effects of acupuncture and the relaxation response in reducing gastrointestinal symptoms, improving medication adherence and quality of life among people living with HIV/AIDS. The study will also explore the mechanism of these therapeutic effects of acupuncture and the relaxation response.

NCT ID: NCT00545558 Completed - HIV Infections Clinical Trials

Effects of Anti-HIV Drugs on the Hepatitis C Virus (HCV) in Adults Infected With Both HCV and HIV

ART and HCV
Start date: April 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to measure the effects of anti-HIV drugs on hepatitis C virus (HCV) viral load in people infected with both HCV and HIV.

NCT ID: NCT00544128 Completed - HIV Infections Clinical Trials

Comparison of Epzicom and Truvada for the Initial Once Daily HIV Treatment

Start date: October 2007
Phase: Phase 4
Study type: Interventional

A non-inferiority randomized control trial in treatment naïve HIV patients to compare virologic effect of two backbone regimens with Epzicom (lamivudine and abacavir) and Truvada (emtricitabine and tenofovir). Both arms are treated with fixed combination of ritonavir boosted atazanavir as key drugs.