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NCT ID: NCT05038969 Completed - Healthy Clinical Trials

Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France)

Start date: March 18, 2021
Phase: Phase 1
Study type: Interventional

Comparative randomized, single dose Bioequivalence Study of Esomeprazole From Stomopral 40 mg Capsules Contain Enteric Coated Pellets (Future Pharmaceuticals Industries, Egypt) and Nexium 40 mg Delayed Release Capsules (AstraZeneca Sweden, Product of France) in Healthy Human Volunteers Under Fasting Condition.

NCT ID: NCT05038787 Completed - Healthy Clinical Trials

A Study of LY3473329 in Healthy Japanese Participants

Start date: November 11, 2021
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and tolerability of LY3473329 in healthy Japanese participants. The study will also assess how fast LY3473329 gets into the blood stream and how long it takes the body to remove it. The study is open to healthy participants. The study will last up to about 71 days, inclusive of screening period.

NCT ID: NCT05037864 Completed - Healthy Clinical Trials

A Comparison of Posture, Balance and Flexibility in Between Adolescent Ballet Dancers and Sedentary Individuals

Start date: October 2, 2021
Phase:
Study type: Observational

Ballet dance are typical specific movement which require balance ability and postural control. Ballet dancers use specific balance exercises. It can be expected, that dancers have an advanced sense of awareness for the placement and motion of their bodies. The effect of ballet dancing on adolescents is still unclear. Therefore, the aim of this study is to determine whether ballet dance has an effect on balance, posture and flexibility in adolescents.

NCT ID: NCT05037578 Completed - Healthy Clinical Trials

Encouraging Cognitive Screenings at African American Churches

Start date: July 1, 2019
Phase: Phase 1
Study type: Interventional

This pilot study plans to examine feasibility and outcomes of a culturally/religiously-tailored church-based dementia screening intervention among older adult African American church members and community members who use church outreach services in 4 African American churches.

NCT ID: NCT05037409 Completed - Healthy Clinical Trials

Investigation of Safety, Tolerability, Immunogenicity and Pharmacokinetics of Single-Dose of PF-06823859 in Japanese Healthy Participants

Start date: September 28, 2021
Phase: Phase 1
Study type: Interventional

Purpose of the study is to evaluate the safety, tolerability, immunogenicity and pharmacokinetics (PK) of PF-06823859 following a single intravenous dose of PF-06823859 300 and 900 mg in Japanese healthy adult participants.

NCT ID: NCT05034575 Completed - Healthy Clinical Trials

Eye Tracking in Laryngology

Start date: June 29, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether eye-tracking technology can be used to differentiate the visual gaze patterns of experienced and novice laryngoscopists while reviewing prerecorded laryngeal videos with both normal and abnormal findings and to characterize any differences arising between level of training groups.

NCT ID: NCT05032144 Completed - Healthy Clinical Trials

The Safety and Tolerability of STSA-1002 Following Intravenous Infusion in Healthy Subjects

Start date: September 28, 2021
Phase: Phase 1
Study type: Interventional

A randomized,double-blind,placebo-controlled,single-ascending dose phase Ⅰa study to evaluate the safety,tolerability,pharmacokinetics and pharmacodynamics of STSA-1002 following intravenous infusion in healthy subjects

NCT ID: NCT05030857 Completed - Healthy Clinical Trials

Drug-drug Interaction and Food-effect Study With GLPG4716 and Midazolam in Healthy Subjects

Start date: September 8, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the effect of the administration of multiple doses of GLPG4716 on the amount of midazolam (MDZ) that gets into the blood when the two drugs are administered together compared to when midazolam is administered alone. Other objectives of this study are to evaluate the safety and tolerability of GLPG4716 when administered with midazolam and assess the amount of GLPG4716 that gets into the blood when administered with midazolam. This study will also assess the effect of food on the amount of GLPG4716 that gets into the blood.

NCT ID: NCT05028673 Completed - Healthy Clinical Trials

A Study to Evaluate a New Tablet Formulation of Lu AG06466 in Healthy Participants

Start date: August 23, 2021
Phase: Phase 1
Study type: Interventional

The main goal of this trial is to learn how a new tablet formulation of Lu AG06466 behaves in the body. Researchers will compare the new tablet formulation to the capsule formulation that is currently being tested in other clinical trials. They will measure the levels of the drug in the bloodstream for up to 3 days after participants take either the tablet or the capsule formulation. They will also look at whether the tablet formulation behaves differently when it is taken with and without food.

NCT ID: NCT05027568 Completed - Healthy Clinical Trials

A Study to Assess an ATX Inhibitor (IOA-289) in Healthy Volunteers

Start date: July 5, 2021
Phase: Phase 1
Study type: Interventional

The purpose of Part 1 of this First-in-Human trial is to evaluate the safety and tolerability after single ascending oral doses of IOA-289 given to healthy male subjects, compared to placebo. After the oral dose administrations, the amount of IOA-289 present in serum will be determined for pharmacokinetic characterisation. Also the reduction of LPA in plasma will be determined as a pharmacodynamic biomarker. Part 2 is optional and its conduct will be dependent on the pharmacokinetic data generated in Part 1. Part 2 will be a randomized, crossover, open label, single oral dose administration of IOA-289 to healthy male subjects either in a fasted state, or after a high-fat meal.