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Healthy clinical trials

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NCT ID: NCT05166096 Completed - Healthy Clinical Trials

Comparative Pharmacokinetic, Pharmacodynamic, and Safety Study of 1 Dose Level of Aspirin for Injection and Oral Aspirin Tablets in Healthy Adult Human Subjects

Start date: December 3, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the safety, pharmacokinetics, and pharmacodynamic effects of aspirin administered intravenously with aspirin administered orally.

NCT ID: NCT05164302 Completed - Healthy Clinical Trials

Skin Surface's Temperature Change When Auricular Acupuncture at Jaw Point and Tooth Point

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Auricular acupuncture is a method for diagnosing and treating physical and psychosomatic dysfunctions by stimulating a specific point in the ear. Some studies prove that the acupoints on the pinna have a corresponding relationship to the areas of the body. Some research also show that acupuncture acupoints on the body can change the temperature of the corresponding area. In our study, we survey the skin surface's temperature change when using auricular acupuncture at jaw point and tooth point in each side of the ear in heatlhy people.

NCT ID: NCT05160363 Completed - Healthy Clinical Trials

A Healthy Volunteer Safety Study of Pyronaridine Tetraphosphate Taken in Combination With Piperaquine Tetraphosphate

Start date: February 14, 2022
Phase: Phase 1
Study type: Interventional

The study is a clinical trial involving two medicines called piperaquine (PQP) and pyronaridine (PYR) which, in combination with dihydroartemisinin (DHA) and with artesunate (ART) respectively, have been in clinical use for over 20 years to treat acute episodes of malaria. PYR and PQP are both known to be well tolerated and provide effective treatment for malarial infection when administered in their licensed combinations, but have not been administered together in combination before. This new combination is being considered for development for malaria prevention (i.e. chemoprophylaxis) in sub-Saharan Africa and therefore, the trial participants will be exclusively drawn from a population from that origin.

NCT ID: NCT05158335 Completed - Healthy Clinical Trials

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of MBX 2109 in Healthy Adult Subjects

Start date: November 10, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of MBX 2109 in healthy volunteers. This study includes 2 parts. Part A involves a single dose of MBX 2109 taken as a subcutaneous (SC) injection just under the skin. Part B involves repeat doses of MBX 2109 taken as a SC injection just under the skin. Each participant will enroll in only one part.

NCT ID: NCT05155995 Completed - Healthy Clinical Trials

A Study to Evaluate the Pharmacokinetics and Safety Between HCP2001 and Co-administration of Each Component in Healthy Volunteers

Start date: September 28, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetic characteristics and safety between HCP2001 and co-administration of each component in fasting and fed conditions respectively in healthy volunteers.

NCT ID: NCT05155306 Completed - Healthy Clinical Trials

A Study in Healthy People to Compare 2 Different Formulations of BI 1358894 Tablets Taken With or Without Food

Start date: January 14, 2022
Phase: Phase 1
Study type: Interventional

To investigate the relative bioavailability of the intended Commercial Formulation (iCF) (Test, T) compared with Trial Formulation 2 (TFII) (Reference, R) and to assess potential food effects following oral administration of BI 1358894.

NCT ID: NCT05155007 Completed - Healthy Clinical Trials

A Study in Healthy Adult Participants to Assess the Effects of Ciclosporin Administration on Rilematovir

Start date: December 10, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetic (PK) of a single-dose of rilematovir co-administered with a single-dose of ciclosporin compared to a single-dose administration of rilematovir alone.

NCT ID: NCT05154409 Completed - Healthy Clinical Trials

Blood and Urine Sample Collection From Healthy Volunteers

Start date: February 22, 2021
Phase:
Study type: Observational

The aim of the study is to obtain blood and urine samples from healthy volunteers to serve as a healthy control group for cross-cohort comparisons.

NCT ID: NCT05154110 Completed - Healthy Clinical Trials

Comparison of Two Techniques for Maintaining Range of Motion

Start date: January 20, 2022
Phase: N/A
Study type: Interventional

Flexibility is a measurable physical capacity considered a key component of physical fitness. Poor flexibility is usually attributed to excessive tension exerted by the antagonist muscles of the movement and supported by weak scientific evidence, static stretching is considered as the most effective intervention in the promotion of muscle extensibility, in attempting to improve mobility.

NCT ID: NCT05153980 Completed - Healthy Clinical Trials

The Impact of Blood Flow Restriction Within Warm-up.

Start date: November 2, 2021
Phase: N/A
Study type: Interventional

Sixty athletes will be randomized in two groups; (1) an experimental group and (2) a control group. Both groups will undergo the following procedure: Moment 1: 1. Baseline testing: countermovement jump, 25m sprint and strength assessment of the Hamstrings and Quadriceps muscle. 2. Short warm-up (approximately 4 minutes), which will be completed with blood flow restriction cuffs (experimental group) or without (control group) 3. Post testing: same tests as performed in baseline. Moment 2: 1. Baseline testing: stiffness measurements of the Biceps Femoris Long Head via Shear Wave Elastography. 2. Short warm-up (approximately 4 minutes), which will be completed with blood flow restriction cuffs (experimental group) or without (control group) 3. Post testing: same tests as performed in baseline. Both moments of testing as well as the order in which the performance tests take place are randomized.