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NCT ID: NCT03364985 Recruiting - Healthy Clinical Trials

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP16001 After Oral Administration in Healthy Male Volunteers

Start date: December 2017
Phase: Phase 1
Study type: Interventional

This is a dose block-randomized, double-blind, placebo- and active-controlled, single and multiple dosing, dose-escalation clinical phase 1 trial to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of DWP16001 after oral administration in healthy male volunteers.

NCT ID: NCT03363984 Recruiting - Healthy Clinical Trials

Pharmacokinetic Interaction Between Midazolam and ID-082 in Healthy Subjects

Start date: November 27, 2017
Phase: Phase 1
Study type: Interventional

A clinical study in healthy male subjects to investigate whether the administration of ID-082 can affect the fate in the body (amount and time of presence in the blood) of midazolam.

NCT ID: NCT03363906 Not yet recruiting - Healthy Clinical Trials

A Study of Dulaglutide in Healthy Participants

Start date: December 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate a new formulation of dulaglutide (study drug) administered under the skin as one injection using a single dose pen compared to three injections using a pre filled syringe. This study will evaluate how much of the study drug enters the body and how long it takes the body to get rid of it. Information about any side effects that may occur will also be collected. The study will last about 84 days, including screening and will require overnight stays in the clinical research unit (CRU).

NCT ID: NCT03363477 Completed - Healthy Clinical Trials

Study of Pharmacodynamic Equivalence of Enoxaparin Rovi to Clexane®, in Healthy Volunteers

Start date: September 25, 2015
Phase: Phase 1
Study type: Interventional

To demonstrate the pharmacodynamic (PD) equivalence of enoxaparin Rovi (100 mg/mL) 100-mg SC injection to Clexane® (100 mg/mL) 100-mg SC injection in healthy volunteers. As secondary objective, to evaluate the safety and tolerability of enoxaparin Rovi (100 mg/mL) in healthy volunteers.

NCT ID: NCT03361605 Enrolling by invitation - Healthy Clinical Trials

Neuroimaging of Anesthetic Modulation of Human Consciousness

Start date: April 12, 2017
Phase: Phase 4
Study type: Interventional

This study's purpose is to see if mental functions take place during different levels of anesthesia, using a commonly used drug (Propofol). fMRI (functional Magnetic Resonance Imaging, or "brain imaging") shows areas in the brain involved in thinking at different depths of anesthesia.

NCT ID: NCT03361566 Recruiting - Healthy Clinical Trials

Short-term Regulation of Energy and Macronutrient Balance: Impact of Energy Flux

EF
Start date: December 1, 2016
Phase: N/A
Study type: Interventional

Aim of the study is to investigate the impact of energy flux (achieved by changes in physical activity) under the conditions of energy balance, caloric restriction and overfeeding in healthy subjects.

NCT ID: NCT03356561 Recruiting - Healthy Clinical Trials

A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Ad26.ZIKV.001 in Healthy Adult Volunteers

Start date: November 26, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, reactogenicity, and immunogenicity of Ad26.ZIKV.001 at 2 dose levels, 5*10^10 viral particles (vp) and 1*10^11 vp, administered intramuscularly as single dose and as 2-dose schedules in healthy adults.

NCT ID: NCT03353636 Completed - Healthy Clinical Trials

Bioavailability of Magnesium Supplements

Start date: June 27, 2016
Phase: N/A
Study type: Interventional

The primary objective of this clinical trial is to demonstrate the superiority of Natural Calm magnesium powder with respect to absorption when compared to three marketed forms of magnesium (two magnesium bisglycinate powders and magnesium citrate capsules). The primary endpoints were serum magnesium AUC (0-8h) and urine magnesium AUC (0-8h) after a single dose of 150 mg elemental magnesium.

NCT ID: NCT03353441 Recruiting - Healthy Clinical Trials

Effects of Microencapsulated Sublingual Glycine (Bidicin) on Cognitive Performance in Healthy Men After an Acute Stressor

Start date: November 2017
Phase: N/A
Study type: Interventional

The aim of this study is to assess whether intake of Glycine (MSG) leads to an increase of cognitive performance after an acute stressor compared to placebo. One group will receive verum, one group placebo and one group will not receive any intervention. Cognitive testing will be performed in connection with the Trier Social Stress Test (TSST).

NCT ID: NCT03352128 Not yet recruiting - Healthy Clinical Trials

Can Creatine Supplementation Reduce the Negative Effect of Mental Fatigue on Cognitive Performance?

MF-Cr
Start date: December 2017
Phase: N/A
Study type: Interventional

To assess whether creatine could play a significant role in postponing mental fatigue. To do so the investigators will seek to increase brain creatine concentration via a creatine supplementation protocol.