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NCT ID: NCT03577886 Recruiting - Healthy Clinical Trials

Safety and Tolerability of CDX-6114 in Healthy Volunteers

Start date: July 4, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of an oral solution of CDX-6114 when administered as a single dose in healthy volunteers.

NCT ID: NCT03577457 Recruiting - Healthy Clinical Trials

The Interaction Between Oxytocin and Serotonin

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The primary objective of this study is to identify any interaction between oxytocin and serotonin on neural and behavioral activity related to social reward and decision making by a double-blind, placebo-controlled, between-subject, pharmacological fMRI design

NCT ID: NCT03577327 Not yet recruiting - Healthy Clinical Trials

The Gut and Skin Microbiome in Vitiligo Disease Progression

Start date: August 2018
Phase:
Study type: Observational

Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls. The investigators aim to answer the question whether the gut and skin microbiome of patients with vitiligo differs from the general population.

NCT ID: NCT03577262 Not yet recruiting - Healthy Clinical Trials

A Non-therapeutic Feasibility Study of the Radioligand [11C]-UCB-J for Imaging Synaptic Density

Start date: June 25, 2018
Phase: Early Phase 1
Study type: Interventional

Up to 20 subjects will receive an injection with [11C]-UCB-J followed by a PET scan on Days 1 and 28

NCT ID: NCT03576144 Recruiting - Healthy Clinical Trials

This Study in Healthy Men Tests How Different Doses of BI 1265162 Are Taken up in the Body and How Well They Are Tolerated.

Start date: July 11, 2018
Phase: Phase 1
Study type: Interventional

The primary objective of this trial is to investigate the safety and tolerability of BI 1265162 in healthy male subjects following inhalative administration of multiple rising doses. Secondary objectives is the exploration of the pharmacokinetics (PK) including dose proportionality and time dependency of BI 1265162 after multiple dosing

NCT ID: NCT03575312 Enrolling by invitation - Healthy Clinical Trials

Pharmacokinetics of Enrofloxacin in Plasma and Urine

EnroHuman
Start date: April 27, 2018
Phase: N/A
Study type: Interventional

Antibiotics like enrofloxacin are widely used in animal farming to treat and prevent bacterial infections. A previous study in poultry farms has shown that yardmen show significant concentrations of administered antibiotics in their urine. It is currently unclear how poultry yardmen are exposed to the administered antibiotics. The objective of this exemplarily study is to obtain information on the pharmacokinetics of the different uptake routes (oral, inhaled or dermal).

NCT ID: NCT03574883 Not yet recruiting - Healthy Clinical Trials

Consciousness Transcranial Alternative Electric STimulation

CONTEST_1
Start date: June 2018
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effect of transcranial Alternating Current Stimulation (tACS) at theta frequency and the the effect of transcranial Direct Current Stimulation (tDCS) on the conscious access to visual stimuli. tACS and tDCS are non-invasive stimulation techniques that are used to induce brain oscillations at certain frequency or to increase the brain activity in applied region. Healthy participants will perform a behavioral task measuring conscious access (visual backward metacontrast masking task) before, during and after fronto-parietal tACS or tDCS stimulation which will increase neural activity in the two sites. This will allow us to examine online and remaining effects of the stimulation and the causal role of fronto-parietal activity on conscious access.

NCT ID: NCT03574285 Enrolling by invitation - Healthy Clinical Trials

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Feeding Conditions

Start date: May 31, 2018
Phase: Phase 1
Study type: Interventional

A Single-dose, Comparative Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Feeding Conditions

NCT ID: NCT03574064 Recruiting - Healthy Clinical Trials

Effects of Gut Peptides on Bone Remodeling

KS-3
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

We will investigate effects of gut hormones on bone remodeling.

NCT ID: NCT03573934 Completed - Healthy Clinical Trials

Gut Hormones and Bone Remodeling in Humans

KS-2
Start date: September 15, 2017
Phase: N/A
Study type: Interventional

Effects of GLP-2 and GIP on bone remodeling in healthy young men.