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Healthy clinical trials

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NCT ID: NCT05193305 Recruiting - Healthy Clinical Trials

Study of Healthy Cohort for Early Detection of Cancer

Start date: February 1, 2023
Phase:
Study type: Observational

Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.

NCT ID: NCT05192395 Completed - Healthy Clinical Trials

A Crossover Study of DWJ1525 to Evaluate the Safety and Pharmacokinetic Properties in Healthy Volunteers

Start date: April 15, 2022
Phase: Phase 1
Study type: Interventional

A Randomized, Open-label, Single Oral Dosing, Two-sequence, and Four-period Crossover Study to Evaluate the Pharmacokinetics and Safety Between the Administration of DWJ1525 and the Co-administration of DWP16001 and DWC202101 for Healthy Subjects in Fed and Fasted State

NCT ID: NCT05191563 Completed - Healthy Clinical Trials

A Study to Compare the Pharmacokinetics, Safety and Tolerability Between Fixed-Dose Combination of HCP1904 and Co-Administration of RLD2001-2 and RLD2006 Tablets in Healthy Subjects.

Start date: July 31, 2021
Phase: Phase 1
Study type: Interventional

An Open-Label, Randomized, Single-Dose Crossover Study to Compare the Pharmacokinetics, Safety and Tolerability Between Fixed-Dose Combination of HCP1904 and Co-Administration of RLD2001-2 and RLD2006 Tablets in Healthy Subjects

NCT ID: NCT05190133 Completed - Healthy Clinical Trials

Drug-drug Interaction Study Between UIC201601 and UIC201602

Start date: May 28, 2016
Phase: Phase 1
Study type: Interventional

An open-label, multiple-dosing, two-arms, one-sequence study to evaluate the safety and pharmacokinetics after co-administration of UIC201601 and UIC201602 in healthy male volunteers.

NCT ID: NCT05189275 Completed - Healthy Clinical Trials

Cannabidiol and Focus Study (CBD-Focus)

CBD-Focus
Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Cannabidiol (CBD), a non-psychoactive hemp derivative, is an attractive therapeutic target, and is most supported by the scientific community as an antiepileptic, anxiolytic, and antipsychotic. Additionally, CBD may cause alterations in aspects of health and fitness, fatigue, stress, calmness, quality of life, cognitive function, ability to maintain focus, sleep quantity, and sleep quality. Cannabidiol may be associated with alterations in inflammatory response in the human body, which has implications in both healthy and diseased populations. Natural killers cells (NKC) play a vital role in maintain your body's defenses and are an essential component of your immune system. In humans, NKC contain the highest concentrations of receptors associated with the endocannabinoid system and CBD. Human models have demonstrated that CBD use increases the percentage of NKC in peripheral blood. However, similar models found that CBD administration inhibits markers of NKC cytotoxic function, a beneficial cellular mechanism used to prevent malignant cell transformation and viral infection. The overarching goal of this investigation is to determine the effects of an 8-week CBD intervention on measures of fatigue, stress, calmness, quality of life, cognitive function, focus, health and fitness, and sleep quantity, and sleep quality. In addition, this study will explore a potential CBD mechanism of action with a focus on biomarkers of neural health, inflammation, liver health, kidney health, as well as NKC number and function.

NCT ID: NCT05187780 Recruiting - Healthy Clinical Trials

Comparison of Reposition Sense in Scoliosis and Healthy Adolescents

Start date: January 22, 2022
Phase:
Study type: Observational

The aim of the study is to compare the spine joint reposition sense in adolescent idiopathic scoliosis and healthy adolescents and to investigate whether there is a difference.

NCT ID: NCT05186311 Completed - Healthy Clinical Trials

BD MiniDraw™ Capillary System Clinical Equivalence Study

Start date: April 22, 2022
Phase:
Study type: Interventional

This study designed to evaluate the safety and effectiveness of a newly developed sample collection device. Participants will be enrolled and samples will be collected by representative future users of the device. Comparator venous and conventional capillary tubes will be collected by skilled healthcare professionals with phlebotomy experience. Samples will be tested and average differences between the investigational device compared to a marketed comparator will be evaluated. Visual observations will be captured and device safety will be assessed.

NCT ID: NCT05186285 Recruiting - Healthy Clinical Trials

Single Ascending Dose Study of CM338 in Healthy Volunteers

Start date: December 11, 2021
Phase: Phase 1
Study type: Interventional

This study was a single-center, randomized, double blind, placebo-controlled, single-dose, dose-increasing study to evaluate the safety, tolerability, PK characteristics, PD effect, and immunogenicity of CM338 injection administered intravenously or subcutaneously at different doses in healthy subjects.

NCT ID: NCT05186090 Completed - Healthy Clinical Trials

Active Gains in Brain Using Exercise During Aging

AGUEDA
Start date: January 2, 2021
Phase: N/A
Study type: Interventional

AGUEDA (Active Gains in brain using Exercise During Aging) is a randomized controlled trial designed to examine the effects of a 24-week resistance exercise program on brain health in cognitively normal adults between 65-80 years of age.

NCT ID: NCT05183880 Withdrawn - Healthy Clinical Trials

Bioavailability of Orally Ingested Vitamin C

ABBA
Start date: November 26, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if crystalline vitamin C supplementation can acutely increase skeletal muscle vitamin C concentrations and if this can be potentiated by administering vitamin C using Phosphycell™ Technology - a phosphatidylcholine-lipid encapsulation technology.