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Healthy clinical trials

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NCT ID: NCT05361096 Completed - Healthy Clinical Trials

The Effect of Flipped Learning Approach

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

This study was conducted to evaluate the effect of flipped learning approach on nursing students' learning of patient safety.

NCT ID: NCT05361005 Completed - Healthy Clinical Trials

Tolerability and Safety of BDB-001 Injection in Healthy Subjects

Start date: March 12, 2020
Phase: Phase 1
Study type: Interventional

A clinical study to evaluate the tolerability, PK and PD characteristics of BDB-001 Injection in healthy subjects.

NCT ID: NCT05360927 Completed - Healthy Clinical Trials

Safety and Tolerability of BDB-001 Injection in Healthy Subjects

Start date: September 25, 2019
Phase: Phase 1
Study type: Interventional

A clinical study to evaluate the safety,tolerability,PK and PD characteristics of BDB-001 Injection in healthy subjects.

NCT ID: NCT05360628 Completed - Healthy Clinical Trials

Evaluation of PK and Safety of D-0120 and Allopurinol

Start date: November 1, 2021
Phase: Early Phase 1
Study type: Interventional

Evaluation of safety and PK interaction between D-0120 and Alopurinol in healthy adult subjects

NCT ID: NCT05359744 Recruiting - Healthy Clinical Trials

Multi-level Molecular Profiling of Peak Performance in Endurance Sports

MSSA
Start date: October 15, 2021
Phase: N/A
Study type: Interventional

Physical activity triggers complex molecular responses, including changes in immune-, stress-, and metabolic pathways. For example, autophagy is essential for energy and cellular homeostasis through protein catabolism, and dysregulation results in compromised proteostasis, reduced exercise performance, and excessive secretion of signaling molecules and inflammatory proteins. However, previous research has been limited by the extend of molecules measured and biological processes covered. A better understanding of these processes through multi-omic analysis can improve knowledge of molecular changes in response to exercise. The main purpose of the investigators study is to analyze the effects of acute exercise in correlation to autophagy and other signaling cascades. Specifically, the investigators plan to perform multi-level molecular profiling in a cohort of healthy male elite cyclists and male and female recreational athletes, before, during, and after a bicycle ergometer test. The results will be compared to a control cohort without intervention.

NCT ID: NCT05357261 Recruiting - Healthy Clinical Trials

Deliver-EE: Evaluating Effects of Meal Delivery

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study will randomly assign 2,300 older adults on waiting lists at nine Meals on Wheels programs in Florida, Texas, North Carolina, South Carolina, and California into two groups who will receive: (a) daily delivery of meals, five days a week or (b) a shipment of 10 frozen meals, every two weeks. Researchers will examine participants' Medicare claims to understand if differences in healthcare utilization occur between the two groups within six months after they start receiving meals. Researchers will also ask participants questions prior to receiving meals, and again at three months, to understand how meals impact their ability to obtain food, their feelings of loneliness, and their overall quality of life. The primary study outcome will be the ratio of days spent in institutional settings (i.e., hospital, nursing home) in the six months after participants begin receiving meals. The secondary outcomes include the ratio of days spent in institutional settings in the three months after participants begin receiving meals, food insecurity, subjective isolation/loneliness, and health-related quality of life. The team will also examine differences in dietary intake between the two groups as an exploratory outcome.

NCT ID: NCT05356143 Completed - Healthy Clinical Trials

A Comparative Study of Rupatadine 10 mg Tablets and Clarinex® 5 mg Tablets Under Fasting Conditions

Start date: December 2, 2021
Phase: Phase 1
Study type: Interventional

This is an open-label, single-dose, randomized, three-period, two-treatment, threesequence, crossover, PK, partial replicate, and comparative bioavailability study. This study may be conducted in groups. The same protocol requirements and procedures will be followed for each group.

NCT ID: NCT05355129 Completed - Healthy Clinical Trials

A Phase 1 Study of TT-00920 in Healthy Subjects

Start date: November 3, 2021
Phase: Phase 1
Study type: Interventional

This is a double-blind, randomized, placebo-controlled, ascending single dose and multiple dose escalation study of TT-00920 in healthy subjects.

NCT ID: NCT05354999 Active, not recruiting - Healthy Clinical Trials

Effects of Combinations of Performance-enhancing Supplements on Exercise Performance

Start date: April 18, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the effect of combinations of creatine monohydrate, sodium bicarbonate and caffeine on exercise performance and fatigability.

NCT ID: NCT05354453 Completed - Healthy Clinical Trials

A Study in Healthy Men to Test How Well Different Doses of BI 1839100 Are Tolerated (1490-0001)

Start date: May 23, 2022
Phase: Phase 1
Study type: Interventional

This trial starts the clinical development of BI 1839100. Effects of single rising doses of BI 1389100 on safety, tolerability and pharmacokinetics will be assessed as basis for further development in patients with pulmonary fibrosis.