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NCT ID: NCT06419634 Not yet recruiting - Clinical trials for Acute Myeloid Leukemia

Study of BMS-986497 (ORM-6151) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Start date: May 30, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, tolerability, drug levels, drug efficacy and determine the recommended dose of BMS-986497 in participants with relapsed or refractory acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

NCT ID: NCT06419608 Recruiting - Clinical trials for Major Depressive Disorder

Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression

Start date: May 28, 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of BHV-7000 in participants with Major Depressive Disorder (MDD)

NCT ID: NCT06419582 Recruiting - Bipolar Disorder Clinical Trials

BHV-7000 Acute Treatment of Bipolar Mania

Start date: May 28, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether BHV-7000 is a safe and effective acute treatment for manic episodes in bipolar disorder I.

NCT ID: NCT06419439 Not yet recruiting - Depression Clinical Trials

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Start date: December 1, 2025
Phase: Phase 2
Study type: Interventional

This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.

NCT ID: NCT06419374 Recruiting - Clinical trials for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Start date: May 24, 2024
Phase: Phase 3
Study type: Interventional

The study will assess the efficacy and safety of pegozafermin administered in participants with compensated cirrhosis due to MASH (biopsy-confirmed fibrosis stage F4 MASH [previously known as nonalcoholic steatohepatitis, NASH]).

NCT ID: NCT06419231 Recruiting - Gut Health Clinical Trials

Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms

Start date: October 31, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms

NCT ID: NCT06419218 Not yet recruiting - Nutrition, Healthy Clinical Trials

Increasing School Meal Participation

Start date: September 2024
Phase: N/A
Study type: Interventional

This study aims to determine whether an online marketing campaign increases children's school meal participation. Parents whose children do not currently eat school meals frequently will be exposed to messages designed to encourage their children's increased participation in school meals.

NCT ID: NCT06419127 Recruiting - Infertility Clinical Trials

Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing

Start date: June 2024
Phase:
Study type: Observational

The goal of this observational study is to discern if there is a relationship between timelapse imagery of human oocytes/embryos and PGT results. Embryos of patients that are undergoing PGT will be placed into a timelapse incubator. The data obtained by the timelapse incubator will be used in conjunction with the PGT data to determine any relationships.

NCT ID: NCT06419075 Not yet recruiting - Clinical trials for Pelvic Organ Prolapse

Tranexamic Acid in Vaginal Reconstructive Surgery

TEXAS
Start date: July 1, 2024
Phase: Phase 4
Study type: Interventional

Tranexamic acid (TXA) has been demonstrated to reduce blood loss in trauma, orthopedic, cardiac, and plastic surgeries in numerous well-designed and adequately powered studies. As a result of this evidence for benefit, TXA is routinely used to reduce blood loss during these surgeries. There are no studies regarding the use of TXA in urogynecology. The investigators seek to explore the effect and safety of local infiltration of TXA in vaginal reconstructive surgery.

NCT ID: NCT06419049 Recruiting - Spina Bifida Clinical Trials

Impact of Standing Programs in Children With Spina Bifida: A Single Subject Design

Start date: February 23, 2023
Phase: N/A
Study type: Interventional

The purpose of this single-subject study is to investigate children with spinal bifida who have significant knee limitations in lower extremity passive range of motion to answer the following research questions: 1. Is a home standing program effective in reducing lower extremity passive range of motion limitations in children with Spina Bifida? 2. Does a home standing program change the quality of functional movement in children with spina bifida? 3. Does a home standing program change a child's performance in daily activities, mobility, and social/cognitive domains? 4. Does a home standing program change a child's health-related quality of life in children with spinal bifida? 5. Does a home standing program result in a change in gait velocity in children with Spina Bifida?