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NCT ID: NCT06380322 Not yet recruiting - Hypertension Clinical Trials

Military Health and Nutrition Examination Study

MHANES
Start date: June 1, 2024
Phase:
Study type: Observational

The Military Health and Nutrition Examination Study (MHANES) is a Department of Defense funded study conducted by Pennington Biomedical Research Center and the US Army Research Institute of Environmental Medicine. This cross-sectional study will assess, in a large, diverse sample of Army Service Members (n=600), food and supplement intake, cardiovascular health, body composition, biomarkers of nutritional status, measures of health status, injury prevalence, mental wellbeing, gut microbiome composition, and physical performance outcomes. The proposed study is modeled after the National Health and Nutrition Examination Survey (NHANES) and customized for the Army population.

NCT ID: NCT06380205 Not yet recruiting - Clinical trials for Healthy Participants

A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult Females

Start date: May 7, 2024
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the drug interaction between povorcitinib and the oral contraceptive levonorgestrel/ethinyl estradiol in healthy adult females.

NCT ID: NCT06380101 Recruiting - Rectal Cancer Clinical Trials

Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC)

NEAAR-LARC
Start date: September 8, 2023
Phase: N/A
Study type: Interventional

This clinical study aims to assess feasibility, safety, tolerability, and compliance of a Nonessential Amino Acid Restriction (NEAAR) medical food in adult patients with locally advanced rectal cancer during standard of care short course radiotherapy followed by standard of care chemotherapy.

NCT ID: NCT06380075 Not yet recruiting - Retinal Disease Clinical Trials

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

COCO-IRD
Start date: May 2024
Phase: N/A
Study type: Interventional

The goal of this research study is to compare two ultrawide field cameras to the gold standard imaging system to evaluate the back of the eye. The main question it aims to answer is the same results and information can be acquired from all of the cameras for evaluating and monitoring inherited retinal diseases (IRDs). Participants will: - undergo pupillary dilation - have photographs taken of the inside of the eyes using three different cameras

NCT ID: NCT06379971 Not yet recruiting - Child Development Clinical Trials

Maternal Choline Supplementation and Cannabis Use During Pregnancy: Impact on Early Brain Development

Start date: May 2024
Phase: Phase 1
Study type: Interventional

The goal of this study is to determine if providing a nutritional supplement, phosphatidylcholine, to pregnant women who have used cannabis products during the current pregnancy improves the offspring's brain-related development during the first 18 months. Participating pregnant women will receive either phosphatidylcholine or a placebo from approximately 16 weeks gestation through birth. The primary outcomes are the child's brain responses to sound at 4 weeks corrected age, and infant behaviors at 3 months and 18 months corrected age as reported by the primary caregiver. Secondary outcomes include motor, socio-emotional, language and cognitive development.

NCT ID: NCT06379919 Recruiting - Wound Irrigation Clinical Trials

Wound Irrigation Comparative Effectiveness Study

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline Irrigation (Group 1) or Irrisept Irrigation (Group 2). Secondary objectives are evaluation of patient reported outcome measures and range of motion in relation to C acnes presence among subjects in the two groups.

NCT ID: NCT06379841 Not yet recruiting - Hysteroscopy Clinical Trials

Green Hysteroscopy

Start date: May 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether green draping in the operating room prior to a hysteroscopy results in a decreased operating room time. Secondary aims are to determine whether there are any differences in infection rate, complication rate, fluid deficit, operating room turnover time

NCT ID: NCT06379425 Recruiting - Pain, Postoperative Clinical Trials

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Start date: March 1, 2024
Phase: Phase 4
Study type: Interventional

This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries. The investigators hypothesize that receipt of acetaminophen, celecoxib and gabapentin preoperatively versus acetaminophen alone will reduce the time to trial of void in patients undergoing same-day minor urogynecologic procedures.

NCT ID: NCT06379321 Not yet recruiting - Recurrence Clinical Trials

A Retrospective/Prospective, Post-market Evaluation of Outcomes of the Triathlon Hinge Knee (THK) System

Hinge
Start date: May 1, 2024
Phase:
Study type: Observational

This study is a prospectively and retrospectively enrolled, post-market, open-label, non-randomized, single institution evaluation of clinical outcomes of primary or revision knee surgery patients who meet the eligibility criteria and received devices from the Triathlon Hinge Knee System according to its indications for use (IFU). Clinical evaluation for all cases will include data collection of patient demographics, surgical details, early postoperative status, functional and clinical outcomes, and survivorship at 1, 2, 6, and 10-years.

NCT ID: NCT06378957 Not yet recruiting - THC Clinical Trials

Behavioral Pharmacology of Orally Administered THC and D-limonene

Start date: September 1, 2024
Phase: Phase 1
Study type: Interventional

The current clinical trial will investigate the effects of orally administered d-limonene (limonene), delta-9-tetrahydrocannabinol (THC) and the combination in healthy adult volunteers.