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NCT ID: NCT06329557 Enrolling by invitation - Clinical trials for Patient Satisfaction

Optimizing the Patient Experience Through Provider Coaching or Communication Intervention

Start date: March 8, 2024
Phase: N/A
Study type: Interventional

Hypothesis: Clinicians who receive patient experience coaching or communication classes have improved patient satisfaction scores and improved clinician satisfaction.

NCT ID: NCT06320860 Enrolling by invitation - Kidney Calculi Clinical Trials

FlexStone Enabled Kidney Stone Retrieval

Start date: March 8, 2024
Phase: N/A
Study type: Interventional

This study investigates if additional basket control in helpful during retrieval of kidney stones especially those that are difficult to reach for standard baskets.

NCT ID: NCT06317766 Enrolling by invitation - Skin Laxity Clinical Trials

Histological Study of the Effects of a 2910 nm Fiber Laser Technology

Start date: February 5, 2024
Phase: N/A
Study type: Interventional

The goal of this interventional clinical study is to conduct a comprehensive evaluation of the 2910 nm fiber laser focusing on its diverse energy settings. 2 subjects will be recruited for this 2 part histology study. The main This study will provide valuable insights into the device's capabilities and expand knowledge of its clinical utility. The first part of this study is intended to optimize treatment parameters based on observed effects at the molecular level. The second part will investigate the state of tissue at different timepoints following treatment. Part 1 Pre-Clinical Study Procedure: - 1 healthy adult (male or female) - 18-75 years of age, who are scheduled to undergo an abdominoplasty (where abdominal skin will be excised) will be recruited. - Informed consent will be obtained by a delegated member of the study staff prior to the day of surgery. - On the day of the scheduled procedure, the laser device will be applied to the skin that will be removed as part of the surgery. The treatment will be completed after induction and prior to prepping for the surgical procedure. Part 2 Clinical Study Procedure: - 1 healthy adult (male or female) - 18-75 years of age, who are scheduled to undergo an abdominoplasty (where abdominal skin will be excised) will be recruited. - Informed consent will be obtained by a delegated member of the study staff prior to the day of surgery. - The study team will utilize the specific setting based off the results of Part 1. - Subject will be asked to return to the site on days -30, -3, -2, -1 before their procedure. - At each visit, subjects will receive a single pulse treatment in areas that will be marked by the study team. - On the day of their procedure, a member of the study team will administer 1 final pulse immediately post-surgery and all 5 timepoints will be harvested for analysis.

NCT ID: NCT06317688 Enrolling by invitation - Breast Feeding Clinical Trials

Effectiveness of Highly Purified Anhydrous (HPA) Lanolin Versus Extra-Virgin Coconut Oil in Preventing Subacute Lactation Mastitis

Start date: November 6, 2023
Phase: Phase 1
Study type: Interventional

Problem of the Study This study was designed to test the effectiveness of the application of extra-virgin coconut oil versus Highly Purified Anhydrous (HPA) Lanolin in ameliorating nipple pain, cracking and eventually the prevention of subacute lactation mastitis in breastfeeding women. It is theorized that the nipple crack, nipple pain are early warning signs of subacute clinical lactation mastitis. Goal is after application of extra-virgin coconut oil comparative analysis will be done at one week, three weeks, and six weeks. These complications associated with development of subacute mastitis can be addressed early during the first six weeks of lactation.

NCT ID: NCT06317194 Enrolling by invitation - Stroke Clinical Trials

A Novel Method of Non-Invasive Brain Stimulation (kTMP) to Enhance Motor Function in Chronic Stroke Patients

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities. The goal of this proposal is to provide a first assessment of the efficacy of an innovative non-invasive brain stimulation system, kTMP, in the treatment of motor impairment following stroke.

NCT ID: NCT06315023 Enrolling by invitation - Clinical trials for Peripheral Arterial Disease

The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)

PTAB1
Start date: October 6, 2023
Phase:
Study type: Observational [Patient Registry]

The purpose of this post-market surveillance study will be to evaluate the real-world use of the DETOUR System in treated patients with symptomatic femoropopliteal lesions from 200 mm to 460 mm in length with chronic total occlusions (100 mm to 425 mm) or diffuse stenosis > 70% who may be considered suboptimal candidates for surgical or alternative endovascular treatments.

NCT ID: NCT06314464 Enrolling by invitation - Clinical trials for Mild Traumatic Brain Injury

Portable Mixed Reality-based Platform for Assessment of Progress in Multisensory Rehabilitation Strategies Post-TBI

Praxis
Start date: February 12, 2024
Phase: N/A
Study type: Interventional

The goal of this comparative pilot study is to provide evidence that Praxis, a portable testbed with low-cost wearable sensors and a mixed reality environment, can deliver effective multisensory rehabilitation exercises with military face-validity in a military service member (SM) population after mild Traumatic Brain Injury (mTBI). The main questions this comparative pilot study aims to answer are: - Can the Praxis testbed provide feasible/acceptable 4-week multisensory rehabilitation for SMs with post-acute mTBI? - Can Praxis detect and influence measurable changes in readiness performance during mTBI recovery? Fifteen SMs with post-acute mTBI from the Center for the Intrepid's Special Operations Performance and Recovery (SPaR) Program will participate in the multisensory vestibular rehabilitation regimen. These SMs will go through 4 weeks of multisensory vestibular rehabilitation including: - gaze stabilization - dual-task balance training - spatial navigation - agility training Data from another fifteen SMs, who will not go through the multisensory rehabilitation regimen and will receive supervised cardiovascular exercise, will be used as the control group. Researchers will compare the Praxis and Control group to determine if the Praxis group shows improvement over the control group with respect to the military-relevant behavioral performance outcomes and patient-reported symptom scores after the end of the rehabilitation.

NCT ID: NCT06309628 Enrolling by invitation - Clinical trials for Lung Transplant Rejection

Analysis of Volatile Organic Compounds in the Breath of Lung Transplant Rejection Patients Using Infrared Spectroscopy

Start date: September 21, 2023
Phase:
Study type: Observational

This study will sample and analyze volatile organic compounds (VOCs) from participants considered to be at risk for developing rejection following lung transplant by using infrared spectroscopy.

NCT ID: NCT06306976 Enrolling by invitation - Clinical trials for Ventral Incisional Hernia

Shear-Wave Elastography

ELASTOGRAPHY
Start date: March 2024
Phase: N/A
Study type: Interventional

Prospective cohort study of patients with midline ventral incisional hernia with a range of hernia morphology who plan to undergo open retromuscular VHR. Study groups: Study groups are selected across a range of morphology and based on factors known or suspected to affect the ability to achieve fascial closure. Control groups: The study plans to enlist 5 volunteers with no incisional hernia or prior laparotomy to establish internal baseline SWE values and interrater reliability. The study will also plan to recruit 5 patients undergoing primary laparotomy in order to correlate SWE findings with closure tension.

NCT ID: NCT06306573 Enrolling by invitation - Clinical trials for Heart Failure NYHA Class III

CardioMEMS HF System Real-World Evidence Post-Approval Study

Start date: December 15, 2022
Phase:
Study type: Observational

The purpose of this post-approval study (PAS) is to evaluate the long-term safety and effectiveness of the CardioMEMS™ HF System using real-world evidence (RWE) methods.