Clinical Trials Logo

Infertility clinical trials

View clinical trials related to Infertility.

Filter by:

NCT ID: NCT03846388 Not yet recruiting - Infertility Clinical Trials

Reproductive Outcome in Assisted Conception Cycles

Start date: March 2019
Phase: N/A
Study type: Interventional

Infertility is the failure to conceive after regular unprotected sexual intercourse for one year. Primary infertility refers woman who has never conceived, and secondary infertility to one who has had a previous pregnancy.The most frequent causes for infertility are ovulatory disorder or anovulation (27-30%) , tubal factor(20-22%), abnormal semen parameters(45-50%). Unexplained infertility refers to infertile couples in whom standard investigations, including tests of ovulation, tubal patency tests and semen analysis are normal. incidence 15-17% of infertile couples. New guidelines on infertility recommend that women with unexplained infertility should be advised for expectant management for 2 years .If pregnancy is not achieved after this period In vitro fertilization Should be considered. The Fast Track and Standard Treatment trial demonstrated A shorter time to pregnancy and higher per cycle pregnancy rates for In vitro fertilization compared with treatment with oral agents or gonadotropins in Patients with unexplained infertility. Successful pregnancy after assisted reproductive technology is influenced by numerous predictors that have been investigated in the previous years. The central predictors of success are the sperm, oocyte quality and endometrial receptivity. Oocyte quality depends mainly on the age of the woman , and her ovarian reserve. Parameters most commonly studied are the woman's age , her antral follicle count , and laboratory tests including serum randomly done during the menstrual cycle levels at day 3 of the cycle.

NCT ID: NCT03843112 Not yet recruiting - Infertility, Female Clinical Trials

Modulating the Vaginal Microbiome After Implantation Failure

Start date: February 2019
Phase: Phase 4
Study type: Interventional

Vaginal microbiome has in studies shown a link with the outcome of fertility treatment. The investigators wish to determine if it is possible to change an unfavorable vaginal microbiome using lactobacilli loaded vaginal supplements.

NCT ID: NCT03836118 Completed - Infertility Clinical Trials

Intrauterine Insemination Predictor Factors

Start date: January 1, 1997
Phase:
Study type: Observational

Multiple studies have reported on the impact of factors such as female age, duration of infertility, type of infertility, hormone levels (i.e. AMH, FSH, estradiol, progesterone), use of different ovarian stimulation protocols, timing/induction of ovulation, number of pre-ovulatory follicles, endometrial thickness by the time of ovulation, sperm parameters (i.e. concentration, progressive motility, morphology, total motile sperm count [TMSC], inseminating motile count [IMC]) and sperm washing procedures. Also the influence of body mass index and smoking on IUI outcome have been studied before. However, results on the predictive value of these parameters remain highly contradictory. The aim of the study is to examine the value of different variables in the prediction of IUI success to develop a clinically useful predictive model of pregnancy and live birth.

NCT ID: NCT03834831 Completed - Male Infertility Clinical Trials

Impact of Coenzyme Q10 and Selenium on Seminal Fluid and Semen Antioxidant Status

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The study was conducted to assess the impact of coenzyme Q10 and selenium on seminal fluid parameters and antioxidant status in infertile men.

NCT ID: NCT03832894 Recruiting - Infertility Clinical Trials

Oestradiol Supplementation in Luteal Long Agonist Fresh In Vitro Fertilization/Intra Cytoplasmic Sperm Injection ( IVF/ICSI) Cycle .

Start date: December 1, 2018
Phase: Phase 3
Study type: Interventional

Whether oestradiol administration affects the pregnancy rate in long agonist fresh IVF/ICSI cycles. Oestradiol level will be measured the day of HCG trigger to assess whether oestradiol level affects cycle outcome results.

NCT ID: NCT03831659 Recruiting - Migraine Clinical Trials

Migraine and Infertility

FERTIMIG
Start date: February 12, 2019
Phase:
Study type: Observational

The purpose of this study is to determine the prevalence of migraine in infertile women and during in Vitro Fertilization protocol. Migraine is two to three times as common in women as in men. Migraine has considerable impact on quality of life. In Vitro Fertilization has become a common therapeutic modality in modern fertility medicines. Treatment protocols are associated with exaggerated hormonal fluctuations. Estrogen is considered to be closely linked to migraine and its fluctuations have been considered to trigger migrainous headaches.

NCT ID: NCT03830723 Not yet recruiting - Infertility Clinical Trials

Personalized Insemination Treatment Study

PITS
Start date: April 1, 2019
Phase: N/A
Study type: Interventional

This study is intended for women undergoing their first cycle of 3 intrauterine inseminations. All 3 inseminations will be personalized by using algorithms to determine the dose of study medication.

NCT ID: NCT03829943 Not yet recruiting - Clinical trials for Vitamin D Deficiency

Vitamin D and Human Sperm DNA Fragmentation

Start date: February 2019
Phase:
Study type: Observational

The purpose of this study will be to investigate if there is a correlation between Vitamin D levels and Sperm DNA Fragmentation. This is a prospective, cohort study. In this study male participants presenting with their partners because of inability to conceive will be recruited for this study. Participants will have a blood sample drawn which will be tested for Vitamin D level. The investigators will then compare sperm DNA fragmentation between normal Vitamin D levels, Vitamin D insufficiency, and Vitamin D deficiency. All infertile males who present to the investigators' infertility clinic have a Semen analysis and Sperm chromatin Structure Assay (SCSA). The research part of the study will be to obtain the Vitamin D level.

NCT ID: NCT03828786 Recruiting - Infertility Clinical Trials

Uterine Scratching in Intra-Uterine Insemination

Start date: July 15, 2018
Phase: N/A
Study type: Interventional

This study will evaluate the potential benefits of uterine injury during the follicular phase of an intra-uterine insemination cycle on the rate of ongoing pregnancy during the first trimester ultrasound.

NCT ID: NCT03826823 Completed - Infertility Clinical Trials

Thin Catheter for Hysterosalpigography

Start date: February 2010
Phase: N/A
Study type: Interventional

Hysterosalpingography is usually painful and the use of thin catheters of IUI could be an attractive alternative . we conducted a randomised controlled trial to compare the standard metal cannula to the thin catheter originally manufactured for intrauterine insemination. Pain assessment was done using visual analogue scale