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NCT ID: NCT02927613 Completed - Clinical trials for Prolonged Mechanical Ventilation

Patient Characteristics, Feasibility, and Outcomes of a Home Mechanical Ventilation Program in a Developing Country

Start date: November 2014
Phase: N/A
Study type: Observational

This study aims to describe the patient characteristics, feasibility, and outcomes of an home mechanical ventilation (HMV) program at a university hospital in Thailand.

NCT ID: NCT02926768 Completed - Clinical trials for Carcinoma, Non-Small-Cell Lung

Phase I/II Study of CK-101 in NSCLC Patients and Other Advanced Solid Tumors

Start date: September 2016
Phase: Phase 1
Study type: Interventional

CK-101 is a novel, potent, small molecule tyrosine kinase inhibitor (TKI) that selectively targets mutant forms of the epidermal growth factor receptor (EGFR) while sparing wild-type (WT) EGFR. The purpose of the study is to evaluate the pharmacokinetic (PK) and safety profile of oral CK-101; to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of oral CK-101; to assess the safety and efficacy of CK-101 in treatment-naive NSCLC patients known to have activating EGFR mutations and previously treated NSCLC patients known to have the T790M EGFR mutation.

NCT ID: NCT02926131 Completed - Jaundice Clinical Trials

A Study to Evaluate a New Jaundice Stick Test

Bilistick
Start date: January 25, 2017
Phase:
Study type: Observational

This is an observational prospective study. The main purpose is to evaluate the stability of the Bilistick system in a humid and hot climate compared to the quantitative test for serum bilirubin (SBR) measurement currently used, the BR-501 total bilirubin meter, kept in a controlled environment. The secondary aim is to assess the operational feasibility of the Bilistick system in a tropical limited-resource setting, when used by locally trained nurses.

NCT ID: NCT02924727 Completed - Clinical trials for Acute Myocardial Infarction

Prospective ARNI vs ACE Inhibitor Trial to DetermIne Superiority in Reducing Heart Failure Events After MI

PARADISE-MI
Start date: December 9, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of LCZ696 titrated to a target dose of 200 mg twice daily, compared to ramipril titrated to a target dose of 5 mg twice daily.

NCT ID: NCT02924376 Completed - Cholangiocarcinoma Clinical Trials

Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202)

Start date: January 16, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is evaluate the efficacy of pemigatinib in subjects with advanced/metastatic or surgically unresectable cholangiocarcinoma with FGFR2 translocation who have failed at least 1 previous treatment.

NCT ID: NCT02922244 Completed - Breast Neoplasms Clinical Trials

Effects of Herbal Products on Reduction of Radiation-induced Dermatitis in Breast Cancer Patients

Start date: May 2016
Phase: N/A
Study type: Interventional

The herbal products on reduction of radiation-induced dermatitis in patients with breast cancer

NCT ID: NCT02919514 Completed - Aging Clinical Trials

Effect of Surfaces on Fall in Elderly

Start date: November 15, 2015
Phase: N/A
Study type: Interventional

To investigate the effects of Thai dance exercises over 6 weeks on functional outcomes and incidence of fall in community-dwelling older individuals. To compare effects of exercise training on hard, soft and sand surfaces in community-dwelling older individuals

NCT ID: NCT02919306 Completed - Clinical trials for Human Immunodeficiency Virus

Safety and Efficacy Study of Vaccine Schedule With Ad26.Mos.HIV and MVA-Mosaic in Human Immunodeficiency Virus (HIV)-Infected Adults

Start date: September 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to assess: 1 safety and tolerability of adenovirus serotype 26 (Ad26) prime and Modified Vaccinia Ankara (MVA) boost versus placebo in participants on suppressive antiretroviral therapy (ART) that was initiated during acute Human Immunodeficiency Virus (HIV) infection; 2) Measure the frequency and duration of sustained viremic control after receiving Ad26 prime/MVA boost or placebo, defined as greater than 24 weeks with plasma HIV ribonucleic acid (RNA) lesser than (<)50 copies/ml after antiretroviral (ARV) analytical treatment interruption (ATI).

NCT ID: NCT02918786 Recruiting - Respiratory Failure Clinical Trials

The Efficacy of the Whisperflow CPAP System Versus Nasal High Flow in Patients at High Risk for Postextubation Failure

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of continuous positive airway pressure (CPAP) delivered by the variable generator WhisperFlow System with high flow nasal cannula oxygen therapy in mechanically ventilated patient who are at risk for postextubation failure.

NCT ID: NCT02917031 Completed - Heart Failure Clinical Trials

Mechanistic Evaluation of Glucose-lowering Strategies in Patients With Heart Failure

MEASURE-HF
Start date: January 10, 2017
Phase: Phase 4
Study type: Interventional

This is a 24 week, multicenter, randomized, double-blind, parallel group, placebo-controlled study to investigate the effects of saxagliptin and sitagliptin on cardiac dimensions and function in patients with type 2 diabetes (T2DM) mellitus and heart failure (HF).