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NCT ID: NCT00220779 Completed - Clinical trials for Multiple Sclerosis, Relapsing-Remitting

Immune Globulin Intravenous (IGIV) To Treat Relapsing, Remitting Multiple Sclerosis

PRIVIG
Start date: December 2002
Phase: Phase 2
Study type: Interventional

The trial will study 2 doses of Immune Globulin Intravenous (Human), 10% Caprylate/Chromatography Purified (IGIV-C) for the number of relapses that occur in a 1 year treatment period.

NCT ID: NCT00216476 Completed - Schizophrenia Clinical Trials

A Study of Relapse Prevention and the Effectiveness of Long-acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder

Start date: October 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether a long-acting injectable formulation of risperidone provides better effectiveness over 2 years, as measured by the time to relapse, compared with quetiapine tablets in a routine psychiatric care setting. Aripiprazole will be investigated in a descriptive manner.

NCT ID: NCT00214578 Completed - Schizophrenia Clinical Trials

Seroquel on Glucose Metabolism

Start date: April 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether six months treatment with the antipsychotic medicine Seroquel (quetiapine) may affect the schizophrenic patient's glucose metabolism

NCT ID: NCT00206310 Completed - Heart Failure Clinical Trials

Crestor Versus Placebo in Subjects With Heart Failure

Start date: September 2003
Phase: Phase 3
Study type: Interventional

The purpose of the study is to investigate if rosuvastatin, added on top of all other medicines prescribed to subjects with symptomatic systolic heart failure, reduces the combined endpoint of cardiovascular death or non-fatal myocardial infarction or non-fatal stroke (time to first event)

NCT ID: NCT00205777 Completed - Osteoporosis Clinical Trials

Study Evaluating Bazedoxifene Acetate In Osteoporosis In Postmenopausal Women

Start date: December 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether bazedoxifene acetate is safe and effective in the treatment of osteoporosis in postmenopausal women.

NCT ID: NCT00205478 Completed - Clinical trials for Rheumatoid Arthritis

Phase 2 Clinical Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the clinical activity and safety of two doses of VX-702 compared to placebo in subjects with moderate to severe Rheumatoid Arthritis.

NCT ID: NCT00196716 Completed - Fabry Disease Clinical Trials

A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease

Start date: June 2003
Phase: Phase 2
Study type: Interventional

People with Fabry disease have an alteration in their genetic material (DNA) which causes a deficiency of the alpha-galactosidase A enzyme. This enzyme helps to break down and remove certain types of fatty substances called "glycolipids." These glycolipids are normally present within the body in most cells. In people with Fabry disease, glycolipids build up in various tissues such as the liver, kidney, skin, and blood vessels because alpha-galactosidase A is not present, or is present in small quantities. The build up of glycolipid levels (also referred to as "globotriaosylceramide" or "GL-3") in these tissues is thought to cause the clinical symptoms that are common to Fabry disease. Symptoms commonly appear during childhood with pain in the hands and feet. This trial is designed to evaluate the efficacy of a lower dose of Fabrazyme in patients who initially received 1.0 mg/kg every 2 weeks of Fabrazyme by investigating if the achieved clearance of glycosphingolipid deposits in the vascular endothelium of the kidney can be maintained at a lower dose.

NCT ID: NCT00195663 Completed - Clinical trials for Early Rheumatoid Arthritis

Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis

PREMIER
Start date: December 2000
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the safety and efficacy of adalimumab in combination with methotrexate in patients with recent onset rheumatoid arthritis (RA), and to assess the long-term safety and maintenance of efficacy after treatment with adalimumab for up to 10 years.

NCT ID: NCT00191919 Completed - Clinical trials for Depressive Disorder, Major

A Randomized Double Blind Study Evaluating Duloxetine in Outpatients With MDD and Pain

Start date: May 2005
Phase: Phase 3
Study type: Interventional

To determine the efficacy of Duloxetine vs. placebo on pain as determined by change in the Brief Pain Inventory (BPI) from baseline over 8 weeks of treatment

NCT ID: NCT00191282 Completed - Clinical trials for Diabetes Mellitus, Type 2

Hyperglycemia and Cardiovascular Outcomes With Type 2 Diabetes

IONM
Start date: October 2002
Phase: Phase 4
Study type: Interventional

The primary objective was to demonstrate a difference between two insulin strategies, one targeting postprandial (PP) hyperglycemia and the other targeting fasting and interprandial hyperglycemia, on time until the first combined adjudicated cardiovascular (CV) event (primary outcome defined as CV death, nonfatal myocardial infarction [MI], nonfatal stroke, coronary revascularization, or hospitalized acute coronary syndrome).