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NCT ID: NCT01699932 Completed - Clinical trials for Type 2 Diabetes Mellitus

Efficacy and Safety of the Fixed Dose Combination of Glimepiride+Metformin in Type 2 Diabetic Patients Inadequately Controlled

LEGEND
Start date: September 2012
Phase: Phase 3
Study type: Interventional

Primary Objective: -To demonstrate the efficacy of a fixed combination of glimepiride + metformin in terms of HbA1c reduction, during 24-week treatment period in patients with inadequately controlled type 2 diabetes mellitus. Secondary Objective: To assess the effects of the fixed combination of glimepiride and metformin at week 24 on: - Percentage of patients reaching HbA1c <7% - Percentage of patients reaching HbA1c <6.5%. - Fasting Plasma Glucose (FPG) - Safety and tolerability

NCT ID: NCT01699048 Completed - Clinical trials for Coronary Artery Disease

The Comparative Effectiveness of Hybrid Revascularization (MIDCAB Then PCI) With DES Versus Multivessel DES PCI or CABG

HREVS
Start date: December 1, 2012
Phase: N/A
Study type: Interventional

Minimally invasive revascularization of the left anterior descending artery followed by stent implantation versus percutaneous coronary intervention or coronary artery bypass in patients with multi-vessel coronary disease

NCT ID: NCT01698554 Completed - Clinical trials for Idiopathic Eyelash Hypotrichosis

Bimatoprost in the Treatment of Eyelash Hypotrichosis

Start date: November 2012
Phase: Phase 3
Study type: Interventional

This study will evaluate the safety and efficacy of bimatoprost solution formulation A compared with bimatoprost solution 0.03% (LATISSE®) and vehicle in the treatment of eyelash hypotrichosis (inadequate eyelashes).

NCT ID: NCT01696279 Completed - Clinical trials for Chronic Kidney Disease

A Study to Assess the Pharmacokinetics of Lanthanum Carbonate, Investigate and Compare the Efficacy, Safety and Tolerability of Lanthanum Carbonate With Calcium Carbonate in Hyperphosphataemic Children and Adolescents With Chronic Kidney Disease on Dialysis

Start date: February 15, 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to summarize the percentage of participants achieving age-specific Kidney Disease Outcomes Quality Initiative (KDOQI) targets for serum phosphorus in hyperphosphatemic children and adolescents with chronic kidney disease (CKD) who are on dialysis, following 8 weeks of treatment with lanthanum carbonate.

NCT ID: NCT01696266 Completed - Clinical trials for Diabetes Mellitus, Type 2

An International Survey on Hypoglycaemia Among Insulin-treated Patients With Diabetes

Start date: September 5, 2012
Phase:
Study type: Observational

This study is conducted in Europe. The aim of the study is to gather information about hypoglycaemia (low blood glucose) among patients with Type 1 or Type 2 diabetes mellitus. The study is both retrospective and prospective.

NCT ID: NCT01695824 Completed - Atrial Fibrillation Clinical Trials

Left Atrial Appendage (LAA) Occluders After Catheter Ablation of Atrial Fibrillation

Start date: December 2011
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess combined end point (All stroke, Systemic embolism, Cardiovascular death) between two groups.

NCT ID: NCT01695239 Completed - Clinical trials for Psoriasis, Arthritic

A Study of Ixekizumab in Participants With Active Psoriatic Arthritis

SPIRIT-P1
Start date: December 2012
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of ixekizumab (LY2439821) compared to placebo in participants with active psoriatic arthritis.

NCT ID: NCT01694485 Completed - Ulcerative Colitis Clinical Trials

Abrilumab (AMG 181) in Adults With Moderate to Severe Ulcerative Colitis

Start date: November 16, 2012
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the effect of abrilumab on induction of remission in adults with moderate to severe ulcerative colitis after 8 weeks of treatment as assessed by a total Mayo Score ≤ 2 points, with no individual subscore > 1 point.

NCT ID: NCT01692301 Completed - Hypertension Clinical Trials

Study of the Safety and Efficacy of LCZ696 on Arterial Stiffness in Elderly Patients With Hypertension

Start date: December 2012
Phase: Phase 2
Study type: Interventional

To examine the efficacy of LCZ696 in comparison to the ARB olmesartan on Central Aortic Systolic Blood Pressure (CASP) and other measures of central hemodynamics and arterial stiffness in elderly patients with an elevated systolic blood pressure (SBP) and widened pulse pressure (PP).

NCT ID: NCT01691859 Completed - Asthma Clinical Trials

MEA112997 Open-label Long Term Extension Safety Study of Mepolizumab in Asthmatic Subjects

Start date: September 28, 2012
Phase: Phase 3
Study type: Interventional

This is a multi-centre, open-label long term safety study of 100 milligrams (mg) mepolizumab administered subcutaneously (SC) in addition to standard of care in subjects who participated in the MEA112997 study. At each clinic visit, adverse events will be assessed and exacerbations will also be reviewed.