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NCT ID: NCT00159536 Completed - Clinical trials for Polycystic Ovary Syndrome

Metformin in Pregnant PCOS Women

PregMet
Start date: February 2005
Phase: Phase 3
Study type: Interventional

To investigate the effect of metformin on pregnancy complications and pregnancy outcome in the II. and III. trimester of pregnancy in women with polycystic ovary syndrome.

NCT ID: NCT00159523 Completed - Asthma Clinical Trials

Impact in Off-spring of Mothers After Perinatal Daily Intake of a Probiotic

Start date: December 2003
Phase: N/A
Study type: Interventional

A probiotic (Lactobacillus rhamnosus GG) supplement to pregnant women the last four weeks of pregnancy and three months after birth is expected to give a 40% reduction in risk of atopic sensitisation and allergic disease at two years of age, compared to placebo.

NCT ID: NCT00158899 Completed - Dyslipidaemia Clinical Trials

GW501516 In Subjects Who Have Low Level Of High-Density Lipoprotein Cholesterol

Start date: August 2004
Phase: Phase 2
Study type: Interventional

The purpose of this clinical research study is to compare up to 3 doses of an investigational drug GW501516 to placebo (an inactive pill that looks like GW501516) to see if it is safe, well tolerated and effective in improving (raising) low levels of "good cholesterol", high-density lipoprotein cholesterol (HDLc), as compared to placebo.

NCT ID: NCT00157261 Terminated - Heart Arrest Clinical Trials

Thrombolysis Using Tenecteplase (Metalyse®) in Cardiac Arrest - The TROICA Trial

Start date: January 2004
Phase: Phase 3
Study type: Interventional

The general aim of this study is to compare the efficacy and safety of tenecteplase to standard treatment during cardiopulmonary resuscitation in patients suffering from out-of-hospital cardiac arrest.

NCT ID: NCT00156234 Recruiting - Clinical trials for Heart Failure, Congestive

Skeletal Muscle Dysfunction in Heart Failure

Start date: March 2005
Phase: N/A
Study type: Interventional

Patients suffering from congestive heart failure report reduced exercise capacity. This skeletal muscle dysfunction is also detectable when using small muscle groups which should not put any demand on the heart. We hypothesize that congestive heart failure has systemic effects that causes the skeletal muscle dysfunction.

NCT ID: NCT00153101 Completed - Clinical trials for Cardiovascular Diseases

Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo.

Start date: November 2001
Phase: Phase 4
Study type: Interventional

The Ongoing Telmisartan Alone and in combination wiht Ramipril Global Endpoint trial (ONTARGET): The primary objectives are to determine if (a) telmisartan 80mg daily and ramipril 10mg daily combination therapy is more effective in reducing the composite endpoint of Cardiovascular Death (CV) death, Myocardial infarction (MI), stroke or hospitalization for Congestive Heart Failure (CHF) compared with ramipril 10mg alone; and (b) telmisartan 80mg daily is at least as effective as (i.e. not less effective than) ramipril 10mg daily, on this endpoint. Telmisartan Randomised Assessment Study in Angiotension converting Enzyme inhibitor intolerant subjects with Cardiovascular Disease. (TRANSCEND): The primary objective of the study is to determine if treatment with telmisartan 80mg daily is superior to placebo reducing the composite endpoint of Cardiovascular Death (CV), Myocardial Infarction ( MI)I, stroke or hospitalization for Congestive Heart Failure (CHF) in patients who are intolerant to Angiotension Converting Enzyme inhibitors.

NCT ID: NCT00153062 Completed - Stroke Clinical Trials

PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes

Start date: August 2003
Phase: Phase 4
Study type: Interventional

The purpose of the trial is to determine if extended-release dipyridamole + aspirin [Aggrenox, Asasa ntin] is superior to clopidogrel [Plavix], and if telmisartan [Micardis, Gliosartan, Kinzal, Kinzalm ono, Predxal, Pritor, Samertan, Telmisartan] is superior to placebo, in the presence of background antihypertensive therapy, in prevention of a second stroke in patients who have recently suffered a stroke and therefore are at high risk of suffering another one.

NCT ID: NCT00153036 Completed - Clinical trials for Cerebrovascular Accident

Rt-PA in the Treatment of Acute Ischemic Stroke

Start date: April 2003
Phase: Phase 3
Study type: Interventional

To collect additional confirmatory data on alteplase(rt-PA) in the European setting and to demonstrate that the treatment of patients between 3 and 4.30 hours of onset of symptoms of acute ischemic stroke with rt-PA compared to placebo-treated patients will result in an improved clinical outcome without increase of fatality rate.

NCT ID: NCT00151788 Terminated - Atherosclerosis Clinical Trials

Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.

Start date: February 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The effects of pactimibe versus placebo on the progression of atherosclerosis in the carotid arteries will be assessed using standard ultrasound techniques.

NCT ID: NCT00149981 No longer available - Clinical trials for Organ Transplantation

A Facilitated Access Program to Provide Everolimus (RAD) Maintenance for Patients Completing Therapy in RAD Trials in Solid Organ Transplantation

Start date: n/a
Phase:
Study type: Expanded Access

Facilitated access to everolimus until it is commercially available and reimbursable by appropriate parties