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NCT ID: NCT03264066 Completed - Solid Tumors Clinical Trials

A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid Tumors

Start date: November 23, 2017
Phase: Phase 2
Study type: Interventional

This is a study to evaluate the efficacy, safety, and pharmacokinetics of cobimetinib plus atezolizumab in participants with advanced solid tumors including the following cohorts: squamous cell carcinoma of the head and neck (SCCHN), urothelial carcinoma (UC), and renal cell carcinoma (RCC).

NCT ID: NCT03263754 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Do Educational Digital Films Enhance Patient COPD Outcomes?

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

This study aims to assess the efficacy of Pocket Medic to promote self-management and pulmonary rehabilitation adherence in COPD patients.

NCT ID: NCT03263637 Completed - Multiple Myeloma Clinical Trials

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Start date: October 24, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary antitumor activity of AZD4573 in subjects with relapsed or refractory haematological malignancies.

NCT ID: NCT03263065 Completed - Constipation Clinical Trials

A Study of the Effect of Bran, Psyllium and Nopal on Intestinal Water Content Using Magnetic Resonance Imaging

NOPAL
Start date: April 18, 2018
Phase: N/A
Study type: Interventional

This study will compare 3 food products (bran, psyllium and nopal) on intestinal water content measured via MRI.

NCT ID: NCT03262935 Completed - Clinical trials for Metastatic Breast Cancer

SYD985 vs. Physician's Choice in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer

TULIP
Start date: December 15, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate that SYD985 [(vic-)trastuzumab duocarmazine] is superior to physician's choice in prolonging progression free survival.

NCT ID: NCT03262376 Completed - Anxiety Clinical Trials

Minerals and Botanicals for Acute Stress

Start date: December 4, 2017
Phase: N/A
Study type: Interventional

The objective of this acute intervention study is to examine the potential of minerals combined with botanicals to demonstrate unique and synergistic effects on oscillatory brain activity, cognitive performance, and stress reduction (endocrine, sympathetic, and subjective parameters) under conditions of acute stress in moderately stressed individuals

NCT ID: NCT03262311 Completed - Cancer Clinical Trials

Pimo Study: Extracellular Vesicle-based Liquid Biopsy to Detect Hypoxia in Tumours

Start date: November 10, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to test the potential of a relatively simple serum assay that aims to identify patient subpopulations whose curative radiotherapy outcome is likely to be compromised by radiobiological tumour hypoxia (prognostic value) and who are most likely to gain (predictive value) from the addition of radiation sensitiser drugs or targeted radiotherapy dose escalation.

NCT ID: NCT03262168 Completed - Heart Diseases Clinical Trials

Supported Exercise Programme for Adults With Congenital Heart Disease

SEACHange
Start date: June 2, 2017
Phase: N/A
Study type: Interventional

This study will evaluate if the introduction of a supported exercise programme can improve physical and psychological well-being for adults with congenital heart disease.

NCT ID: NCT03261687 Completed - Pregnancy Related Clinical Trials

The Effects of a Water Based Exercise Programme and a Land Based Exercise Programme on Women Experiencing Pregnancy Related Pelvic Girdle Pain

Start date: May 27, 2016
Phase: N/A
Study type: Interventional

This study aimed to address whether a water exercise programme improves pain and quality of life in pregnant patients with Pelvic Girdle Pain (PGP) compared to a land-based exercise programme and the feasibility of undertaking a large-scale research programme.

NCT ID: NCT03260933 Completed - Clinical trials for Frail Elderly Syndrome

Integrated Care for Frail Older People

Start date: August 15, 2017
Phase:
Study type: Observational

This is a qualitative interview study investigating patients', carers' and providers' perspectives on integrated care and integrated care pathways for frail older people in Lambeth and Southwark, south London.