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Pregnancy Related clinical trials

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NCT ID: NCT03250884 Recruiting - Pelvic Pain Clinical Trials

Evaluation of the Performance of a Rapid Pregnancy Diagnostic Test.

Start date: August 30, 2016
Phase: N/A
Study type: Observational

The aim of the study is to evaluate the effectiveness of a rapid pregnancy diagnostic test to improve the medical care of patients in emergency room.

NCT ID: NCT03249181 Not yet recruiting - Pregnancy Related Clinical Trials

Dolutegravir in Pregnant HIV Mothers and Their Neonates

DolPHIN-2
Start date: September 2017
Phase: Phase 3
Study type: Interventional

To evaluate dolutegravir (DTG) efficacy in women who present with untreated HIV in late pregnancy. An open-label, multi-centre randomised controlled trial of DTG vs efavirenz-based regimens for women commencing cART in late pregnancy. HIV positive pregnant women presenting with untreated HIV infection in late (≥28 weeks gestation) pregnancy will be randomised 1:1 to receive DTG (50mg once daily) + 2 nucleoside reverse transcriptase inhibitors (NRTIs) or EFV + 2 NRTIs (SoC)

NCT ID: NCT03248219 Recruiting - Obesity Clinical Trials

The Sleep in Pregnancy Study

SiP
Start date: March 15, 2017
Phase: N/A
Study type: Observational

Sleep disordered breathing (SDB) insidiously worsens metabolic function, heightens insulin resistance (IR), and in pregnancy is thought to precipitate gestational diabetes, preterm birth, growth restriction, gestational hypertension, and preeclampsia. Despite the fact that sleep disturbances are common during pregnancy, SDB remains under-recognized, under-diagnosed, and poorly understood, particularly in pregnancies affected by obesity. Sixty percent of pregnancies are now affected by obesity, yet the relationship between SDB, patterns of glycemia, and insulin resistance (IR) in obese pregnant women is a neglected area with major therapeutic implications to improve maternal and infant health. Using a prospective design in which diet and gestational age are highly controlled, the investigators propose to measure SDB (apneas/hypopneas) in obese pregnant women using an ambulatory sleep monitoring system. In parallel, robust patterns of glycemia will be measured with a continuous glucose monitoring system (CGMS), followed by a 75g oral glucose tolerance test to measure insulin action. The investigators global hypothesis is that worse SDB in part accounts for higher 24-hour patterns of glycemia in obese normal glucose tolerant (NGT) pregnant women in their 3rd trimester. We will test the hypothesis that: 1) In obese NGT pregnant women at 32-34 weeks gestation on a controlled eucaloric diet, higher apnea hypopnea index (AHI) will be positively associated with 24-hour glycemia measured by a CGMS and that, 2) Higher AHI in obese NGT pregnant women at 32-34 weeks gestation on a eucaloric controlled diet will be associated with higher insulin resistance measured by a 75g oral glucose tolerance test (Matsuda Model). Early identification and treatment has the potential to decrease long-term maternal cardiovascular morbidity and mortality.

NCT ID: NCT03246919 Not yet recruiting - Clinical trials for Postpartum Hemorrhage

Ideal Time of Oxytocin Infusion During Cesarean Section

I-TOPICS
Start date: August 2017
Phase: Phase 4
Study type: Interventional

This study will evaluate if the timing of oxytocin administration in cesarean deliveries will affect the amount of maternal blood loss. Half of participants will receive oxytocin after delivery of the fetal anterior shoulder and the other half will receive oxytocin after delivery of the placenta. We hypothesize that administering oxytocin after delivery of the shoulder, will result in less overall maternal blood loss.

NCT ID: NCT03244722 Not yet recruiting - Pregnancy Related Clinical Trials

Preconception Maternal Nutrition and Obesity and Impact on Fetal Outcomes, Child Health and Weight

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

This study attempts to understand the association between maternal weight and child weight. Intended participants are both obese and lean women looking to get pregnant in the near future. Obese participants will be randomized to either a structured very low calorie diet or standard-of-care pre-natal dietary counseling. Lean participants will receive standard-of-care pre-natal dietary counseling. From pre-pregnancy through one-year after delivery, both mom and child will participate in tests looking at how their bodies process and store energy. Our hypothesis is that we affect the maternal-child weight association by changing the mother's pre-pregnancy metabolic make up.

NCT ID: NCT03242174 Not yet recruiting - Pregnancy Related Clinical Trials

Health Behaviors in Pregnancy

Start date: August 2017
Phase: N/A
Study type: Observational

To assess health and lifestyle behavior of pregnant women in Baton Rouge including women receiving traditional obstetrical prenatal care and delivering in a hospital and those receiving prenatal care from a midwife and delivering at the birth center.

NCT ID: NCT03232762 Not yet recruiting - Obesity Clinical Trials

Effects of Diet on Pregnancy Outcome and Child Obesity

Start date: September 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to compare 3 different diets in pregnancy, equal in calories, and fats, different in refined grains compared to whole grains as a source of carbohydrates, and in calories from carbohydrate, compared to protein as a source of calories.The hypothesis is that there will be differences in the specified outcomes because the proportions of macronutrients are significant. The primary objective is to detect differences in weight gain.

NCT ID: NCT03231553 Not yet recruiting - Smoking Cessation Clinical Trials

Effectiveness and Cost-effectiveness of a Tailored Text Message Programme (MiQuit) for Smoking Cessation in Pregnancy

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The trial aims to determine whether or not MiQuit (text-message support programme) is effective when offered in addition to standard behavioural support for smoking cessation in pregnancy.

NCT ID: NCT03210870 Recruiting - Pregnancy Related Clinical Trials

Clatsop Astoria Maternal Partnership Study (CAMPS) - Healthy Eating in Pregnancy Intervention

CAMPS
Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Purpose of this study is to learn more about how nutritional advice given during pregnancy affects a mother's food choices and her baby's growth.

NCT ID: NCT03209557 Recruiting - Clinical trials for Tobacco Use Cessation

Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women

Start date: July 5, 2017
Phase: N/A
Study type: Interventional

Investigators will assess the feasibility of implementing a randomized control trial of a behavioral intervention that uses smartwatch technology to monitor smoking behavior with texts aimed at reducing smoking in pregnant women who smoke. Investigators will compare the cessation rate of pregnant women who receive usual care through programs aimed at reducing smoking with pregnant women who receive usual care and are using the SmokeBeat app with a smartwatch.