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NCT ID: NCT00234364 Completed - Parkinson's Disease Clinical Trials

Pergolide Treatment and Valvular Heart Disease

Start date: March 2005
Phase: N/A
Study type: Observational

In a blinded echocardiographic study we investigate the frequency of valvular abnormalities in a group of Parkinson patients treated with either ergot derived dopamine agonists (pergolide and cabergoline) or non-ergot derived dopamine agonists (pramipexole and ropinirole). The ability to detect patients with valvular abnormalities by clinical approach is examined.

NCT ID: NCT00233662 Completed - Clinical trials for Chronic Plaque Psoriasis

Safety and Tolerability of Repeat Courses of IM Alefacept

Start date: December 1, 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether repeat courses of alefacept, administered intramuscularly, are safe when given to chronic plaque psoriasis patients who are receiving standard dermatology treatments.

NCT ID: NCT00233584 Completed - Asthma Clinical Trials

Pulmicort Asthma Prevention (Post-PAC)

Start date: July 2001
Phase: N/A
Study type: Interventional

This prospective study will evaluate the feasibility of the defined decision tree for the treatment of asthmatic young children. Children who develop episode (=3 consecutive days) of any troublesome lower respiratory symptoms are treated according to a strictly pre-defined multi-steps treatment algorithm until the age of 6 years.

NCT ID: NCT00233441 Completed - Atrial Fibrillation Clinical Trials

Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/Flutter

MAIA
Start date: December 2004
Phase: Phase 2/Phase 3
Study type: Interventional

Double blind study to evaluate the efficacy and tolerability of SSR149744C and select a dose to be further investigated in the maintenance of sinus rhythm after electrical, pharmacological or spontaneous conversion of AF/AFL.

NCT ID: NCT00232674 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Efficacy Study of the Effect of Budesonide on Emphysema

Start date: July 1999
Phase: Phase 4
Study type: Interventional

To assess the effect of up to 4 years treatment with budesonide on progression of emphysema in patients with Chronic Obstructive Lung Disease.

NCT ID: NCT00232401 Completed - Healthy Clinical Trials

The Circadian Rhythm of Urine Output in Healthy Infants

Start date: October 2005
Phase: N/A
Study type: Observational

The purpose of this study is to describe the 24-hour urine output including the urinary excretion of hormones, electrolytes and other osmotically active substances in healthy children age 0 to 3 years old.

NCT ID: NCT00231114 Completed - Asthma Clinical Trials

Asthma Intervention Research 2 (AIR2) Trial

Start date: September 2005
Phase: N/A
Study type: Interventional

The objective of this randomized, double blind, sham-controlled study is to demonstrate the safety and effectiveness of the Alair System in a population of subjects with severe asthma who are still symptomatic despite being managed on conventional therapy of high doses of inhaled corticosteroids and long-acting β2-agonists. The primary efficacy endpoint will be the difference between Study groups in the change in Asthma Quality of Life Questionnaire (AQLQ) score from Baseline and the average score from the 6-, 9-, and 12-month follow-up visits. All other outcome measures assessed at 12 months post-treatment. This will be a multicenter, randomized, double-blind, sham-controlled study comparing the effects of treatment with the Alair System to conventional therapy of inhaled corticosteroids (ICS) and long-acting β2-agonists (LABA). A Bayesian adaptive approach to sample size selection is used with a randomization scheme of 2:1 (two Alair Group Subjects for every one Control Group Subject).

NCT ID: NCT00230971 Completed - Appendicitis Clinical Trials

Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)

Start date: October 2005
Phase: Phase 4
Study type: Interventional

This is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment. Safety evaluations will occur through the treatment and post-treatment periods and continue through resolution or stability of the adverse event(s).

NCT ID: NCT00230360 Completed - Constipation Clinical Trials

Diagnosis of Functional Defecation Disorders in Childhood

Start date: June 2005
Phase: N/A
Study type: Observational

Purpose To compare different kinds of diagnostic investigations in order to identify the most sensitive and least invasive when diagnosing constipation.

NCT ID: NCT00229697 Completed - Breast Neoplasms Clinical Trials

Phase II Metastatic ER+/PgR+ Nolvadex +/- Iressa Study

Start date: October 2003
Phase: Phase 2
Study type: Interventional

This study is being carried out to see if ZD1839 is effective in treating metastatic breast cancer in combination with Nolvadex, and if so, how it compares with Nolvadex alone.