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NCT ID: NCT01212666 Completed - Clinical trials for Anterior Cruciate Ligament Reconstruction

The Efficacy of Adductor-Canal-Block (ACB) in Patients After Anterior Cruciate Ligament (ACL) Reconstruction

Start date: May 2010
Phase: Phase 4
Study type: Interventional

The Purpose of this study is to determine whether Adductor-Canal-Block is superior to placebo when it comes to analgetic efficacy after reconstruction of the anterior cruciate ligament.

NCT ID: NCT01212575 Completed - Schizophrenia Clinical Trials

A Retrospective NIS to Evaluate the Use of Seroquel XR and IR in the Clinical Practice of Outpatients With Schizophrenia

Start date: October 2010
Phase: N/A
Study type: Observational

The primary objective of this non-interventional study is to investigate how Seroquel XR and Seroquel IR are used in the clinical practice of outpatients with schizophrenia. This will be done by a retrospective review of medical records to evaluate patients treated with Seroquel XR or Seroquel IR as primary antipsychotic treatment.

NCT ID: NCT01210196 Completed - Fabry Disease Clinical Trials

Sophisticated Assessment of Disease Burden in Patients With Fabry Disease

SOPHIA
Start date: October 31, 2010
Phase:
Study type: Observational

To detect early signs of cardiac and metabolic alterations as well as to evaluate the progression of cardiac and metabolic impairments in mildly affected patients with Fabry Disease using high sensitive diagnostic methods.

NCT ID: NCT01209429 Completed - Healthy Clinical Trials

Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction

Start date: September 2010
Phase: N/A
Study type: Interventional

This study will investigate whether growth hormone is modulated by the enzyme SIRT1 and by that is stimulating lipolysis on expense of IGF-I production. This is done in 10 healthy men on calorie restriction on 4 study days with fat and skeletal muscle biopsies.

NCT ID: NCT01209416 Completed - Insulin Resistance Clinical Trials

The Effect of Pharmacological Antilipolysis on the Metabolic Effects of Ghrelin

Start date: June 2012
Phase: N/A
Study type: Interventional

This study will investigate the non-growth-hormone-dependent metabolic effects of the hormone Ghrelin in growth hormone deficient subjects by examining the insulin tolerance as well as signal proteins in fat and muscle biopsies.

NCT ID: NCT01209403 Completed - Clinical trials for Kidney Failure, Chronic

Insulin-like Growth Factor (IGF-I) in Hemodialysis Patients

Start date: September 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate whether the anabolic potentials of insulin may be used to reverse the catabolic effects of hemodialysis in non-diabetic patients with end-stage renal failure.

NCT ID: NCT01208701 Completed - Clinical trials for Cardiovascular Diseases

The Effects of Atorvastatin on the Nitrogen Oxide-system in Patients With Type 2 Diabetes and Nephropathy

STAD
Start date: May 2010
Phase: Phase 2
Study type: Interventional

It has been documented that statin reduce mortality and morbidity in patients with cardiovascular disease. This effect can partly be related to a reduction in cholesterol levels in blood. Nitric oxide (NO) production is reduced in several chronic diseases such as nephropathy, diabetes and hypertension. The purpose of this study is to investigate the effect of Atorvastatin treatment on the NO-system measuring renal and cardiovascular variables in patients with type 2 diabetes with nephropathy.

NCT ID: NCT01208090 Completed - Psoriasis Clinical Trials

ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis

Start date: October 31, 2010
Phase: Phase 2
Study type: Interventional

This study will assess the efficacy, safety and tolerability of two doses of ACT 128800 in patients with moderate-to-severe chronic plaque psoriasis.

NCT ID: NCT01206881 Completed - Breast Cancer Clinical Trials

Neoadjuvant Pegylated Liposomal Doxorubicin and Cyclophosphamide +/- Trastuzumab Followed by Docetaxel in Breast Cancer

Start date: March 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy of neoadjuvant treatment with pegylated liposomal doxorubicin (Caelyx) and cyclophosphamide +/- trastuzumab followed by docetaxel in patients with locally advanced, inflammatory breast cancer or with a primary tumor > 5 cm.

NCT ID: NCT01206049 Completed - Cholangiocarcinoma Clinical Trials

Combination Chemotherapy Plus Panitumumab or Bevacizumab for Inoperable Cholangiocarcinoma Without KRAS Mutations

GOC-B-P
Start date: September 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the rate of progression free survival of patients with inoperable cholangiocarcinoma 6 months after enrollment in the study. The patients are treated with combination chemotherapy supplemented by biological agents panitumumab or bevacizumab.