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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT03504852 Not yet recruiting - Clinical trials for Moderate to Severe Chronic Plaque-type Psoriasis

Efficacy and Safety of 2 Secukinumab Regimens in 90 kg or Higher Subjects With Moderate to Severe Chronic Plaque-type Psoriasis

Start date: June 19, 2018
Phase: Phase 3
Study type: Interventional

Demonstrate superiority of secukinumab high dose over standard dose in heavy body weight subjects with moderate to severe plaque psoriasis.

NCT ID: NCT03493269 Not yet recruiting - Healthy Volunteers Clinical Trials

A Multiple Dose Study of BAY1834845 in Healthy Male Subjects and in Patients With Rheumatoid Arthritis (RA) or Psoriasis

Start date: April 16, 2018
Phase: Phase 1
Study type: Interventional

To assess safety and tolerability of multiple oral doses of BAY1834845 in healthy male subjects (Part 1) and in patients with RA or psoriasis (Part 2) To assess the pharmacokinetic (PK) properties of total BAY 1834845 in plasma after oral multiple doses of BAY1834845 in healthy male subjects (Part 1) and patients with RA or psoriasis (Part 2)

NCT ID: NCT03492632 Recruiting - Psoriasis Clinical Trials

Ovarian Reserve in Patients With Psoriasis

Start date: April 2, 2018
Phase:
Study type: Observational

Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Autoimmune diseases including psoriasis are linked to premature ovarian reserve. This study aims to measure serum hormones including FSH,LH,E2,PRL and AMH (indicators of ovarian reserve) in women with and without psoriasis.

NCT ID: NCT03485560 Not yet recruiting - Psoriasis Clinical Trials

Revitalization of Damaged Skin Due to Chronic Skin Diseases

Start date: May 1, 2018
Phase: Early Phase 1
Study type: Interventional

Chronic skin disease lead to skin damage and disfiguring to the patient skin. Sometimes, achieving normal skin is not possible by the normal traditional treatment, this study is focusing on use of ACE CSD formula which is mixture of natural peptides and herbs. the main aim is to restore the normal skin appearance for the patient and control the episodes of flare.

NCT ID: NCT03483311 Recruiting - Psoriasis Clinical Trials

Resolvin D1 in Psoriasis Before and After Narrowband UVB Phototherapy

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

• Assessment of tissue level of resolvin D1 in psoriasis in comparison to its level in healthy controls in order to verify its role in the pathogenesis of psoriasis.

NCT ID: NCT03482011 Not yet recruiting - Psoriasis Clinical Trials

A Study to Evaluate the Efficacy and Safety of Mirikizumab (LY3074828) in Participants With Moderate-to-Severe Plaque Psoriasis

OASIS-1
Start date: April 26, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of mirikizumab in participants with moderate to severe plaque psoriasis.

NCT ID: NCT03478787 Not yet recruiting - Psoriasis Clinical Trials

Risankizumab Versus Secukinumab for Subjects With Moderate to Severe Plaque Psoriasis

Start date: May 9, 2018
Phase: Phase 3
Study type: Interventional

The main objective of this study is to evaluate the efficacy and safety of risankizumab compared with secukinumab for the treatment of adult subjects with moderate to severe plaque psoriasis who are candidates for systemic therapy.

NCT ID: NCT03478280 Not yet recruiting - Psoriasis Clinical Trials

Effect of Brodalumab Compared to Placebo on Vascular Inflammation in Moderate-to-severe Psoriasis

Start date: April 15, 2018
Phase: Phase 4
Study type: Interventional

A randomised, double-blind, placebo-controlled, trial to evaluate the efficacy of brodalumab monotherapy on vascular and systemic inflammation by 18F-FDG-PET/CT in subjects with moderate-to-severe plaque-type psoriasis who are candidates for systemic therapy

NCT ID: NCT03475914 Completed - Psoriasis Clinical Trials

Characterization of Cutaneous Microbiota in the Psoriasis Pathogenesis

MICROBIOTA
Start date: October 13, 2016
Phase:
Study type: Observational [Patient Registry]

The skin harbors a complex and dynamic microbiota constituted by numerous microorganisms that live in symbiosis with the host. The specific etiology of psoriasis is still not-well understood; nonetheless several studies highlighted that that the skin microbiota could have a pivotal role in the maintenance and/or progression of the disease, acting as microbial predictor of psoriasis however. The aim of the present study was to characterize the microbiota of cutaneous biopsies associated to guttate and vulgaris psoriasis, both considering lesion and healthy skin belonging to the same psoriatic subject.

NCT ID: NCT03469336 Not yet recruiting - Psoriasis Clinical Trials

Safety, Tolerability And Efficacy Study Of Topical PF-06763809 In Subjects With Mild To Moderate Chronic Plaque Psoriasis

Start date: April 17, 2018
Phase: Phase 1
Study type: Interventional

The study is a randomized, double blinded, vehicle and active comparator controlled, multiple dose study in subjects with chronic plaque psoriasis. The study will have approximately 15 completers. Each subjects will receive three different topical doses of PF 06763809, PF 06763809 vehicle, and two active comparators. These will be applied to six different treatment fields for 18 days. The total duration of participation in the study will be approximately 7 weeks (minimum) to approximately 11 weeks (maximum), including the interval from Screening to the Follow up phone call visit.