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NCT ID: NCT03948425 Completed - Stroke, Acute Clinical Trials

Cerebral Dynamic Perfusion Study With Spectral CT in Patients Suspected of Stroke

AVC_AIGUS
Start date: June 8, 2017
Phase: N/A
Study type: Interventional

- Generate a dynamic mapping of the distribution of iodine within the cerebral parenchyma in the patient suspected of acute ischemic disorder with the CT spectral scanner. - Correlate the anomalies of iodine mapping to the other parameters acquired during the classic dynamic infusion phase to define the ischemic area (MTT higher and rCBV normal) versus infarcted zone (MTT higher and rCBV decreased)

NCT ID: NCT03947398 Completed - Clinical trials for Percutaneous Coronary Intervention

The BLIMP Balloon in Coronary Interventions

Start date: March 28, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effectivness of the Blimp Scoring balloon compared to current available CTO balloon catheters.

NCT ID: NCT03945942 Completed - Clinical trials for Liver Transplant; Complications

Influence of Hyperbilirubinaemia on Two Different Near Infrared Spectroscopy Devices

NIRS_GREFFE
Start date: March 15, 2019
Phase: N/A
Study type: Interventional

Protocol Near infrared spectroscopy liver transplants: comparison of two monitoring of Near infrared spectroscopy in pediatric liver transplant.

NCT ID: NCT03945539 Completed - Healthy Clinical Trials

A Study to Evaluate the Effect of Itraconazole on JNJ-56136379 in Healthy Adult Participants

Start date: May 15, 2019
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to assess the effect of itraconazole at steady-state on a single-dose pharmacokinetic (PK) of JNJ-56136379 in healthy adult participants.

NCT ID: NCT03945188 Completed - Ulcerative Colitis Clinical Trials

Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis

ELEVATE UC 52
Start date: June 13, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for moderately to severely active ulcerative colitis.

NCT ID: NCT03943732 Completed - Pneumonia Clinical Trials

Trial Measuring the Clinical Impact of the FilmArray® Pneumonia Panel in Critically Ill

FA-PNEU
Start date: May 27, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to measure how the use of Film-Array Pneumonia (FA-PNEU) on respiratory samples of adult patients suspected of acute care pneumonia in the intensive care unit of Saint-Luc University Hospital can accelerate / improve the initiation of the optimal antibiotic treatment.

NCT ID: NCT03943719 Completed - Septicemia Clinical Trials

Clinical Impact of the FilmArray Blood Culture Identification Panel Performed on Positive Blood Cultures From Intensive Care Patients With Septicemia

SEPSIS2016
Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

Molecular testing is a largely validated approach allowing rapid identification of positive blood cultures. However, due to its high cost and its limited information on susceptibility, it is considered as an add-on technique reserved for specific patient populations. In our study, we specifically evaluated molecular testing in a critical care setting and measured its impact on the therapeutic management of critically ill with positive blood cultures. Through the analysis of 110 positive blood culture episodes included in both pre- and post intervention period, we measured a drastic 14h-reduction of the time to administration of the optimal antimicrobial treatment with the use of the molecular approach.

NCT ID: NCT03943563 Completed - Clinical trials for Arthritis, Rheumatoid

Compare Diagnostic Performance of DIXON &CHESS Sequences Calculating RAMRIS Score in Early Rheumatoid Arthritis.

IDEAL PR
Start date: May 13, 2016
Phase: N/A
Study type: Interventional

In a preliminary MRI study of healthy volunteers's hands investigators showed that the suppression of the fat signal obtained by the Dixon sequences is greater than that obtained by the "classic" CHESS sequences with a better T1-weighted image quality. The investigators goal now is to compare these sequences in the quantification of the inflammatory activity of rheumatoid arthritis by the RAMRIS score. To investigators knowledge, only one study compared those two types of sequence with many limitations including a limited number of patients included.

NCT ID: NCT03942666 Completed - Asthma Clinical Trials

PK Linearity and Steady State PK of CHF 6532 in Healthy Subjects

Start date: May 10, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this clinical pharmacology study is to evaluate the CHF 6532 linearity after single oral administrations of four doses of a tablet formulation and to evaluate the pharmacokinetic (PK) at steady state following the repeated open label b.i.d. administration at one dose.

NCT ID: NCT03941353 Completed - Hip Fractures Clinical Trials

Care Pathways for Benchmarking on Fragile Hip Fractures Rapid Recovery

Start date: January 1, 2020
Phase:
Study type: Observational

The aim of this project is to build an international community of centers of excellence in the care for Fragile Hip Fracture Rapid Recovery patients. These centers of excellence will benchmark and share their expertise and experiences based on clinical and managerial data. In project is designed in five different phase: Phase 1: literature review: identifying relevant key interventions and indicators Phase 2: expert panel: expert panel for teams, management and policy makers Phase 3: data collection: collection managerial data through retrospective patient record analysis on clinical indicators Phase 4: statistical data analysis: data input, validation and statistical analysis Phase 5: feedback and knowledge sharing: feedback report with anonymous benchmarking and knowledge sharing of the results.