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NCT ID: NCT03940196 Completed - Ovarian Cancer Clinical Trials

Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)

Start date: March 22, 2019
Phase: Phase 3
Study type: Interventional

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) concomitant with weekly paclitaxel for the treatment of recurrent ovarian cancer . The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays.

NCT ID: NCT03939767 Completed - Clinical trials for Wet Age-related Macular Degeneration

Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease

XTEND
Start date: May 12, 2019
Phase:
Study type: Observational

In this observational study researchers want to learn more about changes in visual acuity (clarity of vision) with proactive flexible treatments over time in patients suffering from wet age-related macular degeneration (wAMD) after decision to treat with Aflibercept (Eylea) was made. Wet AMD is an eye disease that progressively destroys the macula, the central portion of the retina, impairing central vision.

NCT ID: NCT03938558 Completed - Multiple Sclerosis Clinical Trials

Art for MS - Controlled Trial

Start date: August 28, 2018
Phase: N/A
Study type: Interventional

This study is a controlled pilot study with 17 participants with Multiple Sclerosis (MS). The primary goal of this study is to objectively examine the effects of a multimodal dance intervention on walking-related performance fatigability. The secondary aim is to investigate the effects of a multimodal dance intervention on other MS symptoms related to fatigue and fatigability. The following research questions will be addressed: 1. Does a multimodal dance intervention have positive effects on walking-related fatigability? 2. Does a multimodal dance intervention have positive effects on other MS symptoms related to fatigue and fatigability?

NCT ID: NCT03938142 Completed - Chronic Pain Clinical Trials

Goalsetting in Patients With Chronic Pain: a European Survey

Start date: November 23, 2019
Phase:
Study type: Observational

The aim of this survey is to get insight in the individual goals of chronic pain patients according to the ICF framework.

NCT ID: NCT03937180 Completed - Clinical trials for Benzodiazepine Dependence

Blended Care for the Discontinuation of Benzodiazepine Use

Big Bird
Start date: June 24, 2019
Phase: N/A
Study type: Interventional

This study aims to compare two strategies performed by GPs to help patients taking benzodiazepines on a daily basis for at least six months to discontinue their use. The first strategy consists of the usual or standard support provided by the GP, which often starts with a discontinuation advice or letter, the second is blended support where face-to-face consultations with the GP are alternated with web-based self-learning by the patient.

NCT ID: NCT03936959 Completed - Advanced Cancer Clinical Trials

A Study of LY3434172, a PD-1 and PD-L1 Bispecific Antibody, in Advanced Cancer

Start date: May 24, 2019
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to evaluate the safety and tolerability of the study drug LY3434172, a PD-1/PD-L1 bispecific antibody, in participants with advanced solid tumors.

NCT ID: NCT03934216 Completed - Ulcerative Colitis Clinical Trials

Safety and Efficacy of Deucravacitinib in Participants With Moderate to Severe Ulcerative Colitis

Start date: July 1, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of oral deucravacitinib in participants with moderate to severe ulcerative colitis (UC).

NCT ID: NCT03931447 Completed - Healthy Clinical Trials

A Safety and Tolerability Study of JNJ-72537634 in Healthy Participants

Start date: April 30, 2019
Phase: Phase 1
Study type: Interventional

The purpose of the study is to assess the safety and tolerability of JNJ-72537634 compared with placebo in healthy participants after administration of single and multiple day doses.

NCT ID: NCT03931278 Completed - Multiple Sclerosis Clinical Trials

Sonification Embodied Associations

Start date: December 18, 2018
Phase: N/A
Study type: Interventional

The objective of this study to investigate, if learning and recall of a sequence of body movements (steps that realize a pattern on the ground) can be improved by self-produced music (having particular melodic-structures in relation to the pattern), compared to the same sound (a single tone) for each pattern in persons with multiple sclerosis compared to age and gender matched controls

NCT ID: NCT03930836 Completed - Cerebral Palsy Clinical Trials

Implementation of a New Motor Skill Learning Therapeutic Device in Children With Cerebral Palsy Rehabilitation

Start date: June 14, 2018
Phase: N/A
Study type: Interventional

Study of the efficiency of a new interactive interface to apply all the therapeutic principles of motor skill learning used in high dosage intensive interventions. Investigation of its effects on motor, functional and neuroplastic changes in children after high and low dosage intensive interventions using or not the interface.