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NCT ID: NCT03959488 Completed - Clinical trials for Respiratory Syncytial Virus Infections

A Study to Evaluate the Safety of MEDI8897 for the Prevention of Medically Attended Respiratory Syncytial Virus(RSV) Lower Respiratory Track Infection (LRTI) in High-risk Children

Start date: July 30, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of MEDI8897 compared to palivizumab when administered to preterm infants entering their first RSV season and children with chronic lung disease (CLD) and congenital heart disease (CHD) entering their first and second RSV season.

NCT ID: NCT03959137 Completed - Clinical trials for Stage IV Non-small Cell Lung Cancer

BEPACT- Lung: Impact of Patient Characteristics on Pneumo-oncologists Non Small Cell Lung Cancer (NSCLC) Systemic Treatment Decision in Belgium

BEPACT- Lung
Start date: June 3, 2019
Phase:
Study type: Observational

The treatment landscape of metastatic non small cell lung cancer (NSCLC) is rapidly evolving. There are new diagnostic and treatment options available in the coming months and years. New combination treatments will give different solutions to pneumo-oncologists who might be guided by certain patient and tumor characteristics. The link between patient and tumor characteristics in untreated stage IV non small cell lung cancer (NSCLC) patients and systemic treatment needs further investigation, allowing the identification of possible treatment issues, data gaps and/or areas of improvement.

NCT ID: NCT03956615 Completed - Multiple Myeloma Clinical Trials

sdAb-based TRNT of Multiple Myeloma: a Feasibility Study

MUM
Start date: February 12, 2019
Phase: N/A
Study type: Interventional

This study aims to show that antiidiotypic sdAb are a new, sensitive, specific and non-invasive tool for imaging and therapeutic purposes and provides a rationale for their clinical evaluation as a personalized treatment option for MM patients expressing surface paraprotein.

NCT ID: NCT03955939 Completed - Clinical trials for Metastatic Breast Cancer

A Study of LY3295668 Erbumine in Participants With Breast Cancer That Has Spread to Other Parts of the Body

Start date: August 2, 2019
Phase: Phase 1
Study type: Interventional

The reason for this study is to determine the recommended phase 2 dose of the study drug LY3295668 erbumine in participants with breast cancer that has spread to other parts of the body.

NCT ID: NCT03955913 Completed - Urothelial Cancer Clinical Trials

A Study to Identify Participants With Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations

Start date: August 1, 2019
Phase:
Study type: Observational

The purpose of this non-interventional study is to identify participants with urothelial cancer (UC) and selected fibroblast growth factor receptor (FGFR) aberrations through molecular testing of their archival tumor tissue.

NCT ID: NCT03955081 Completed - Small Bowel Disease Clinical Trials

A Clinical Study With the Medical Device PowerSpiral for Deep Enteroscopy

SAMISEN
Start date: September 2, 2019
Phase:
Study type: Observational [Patient Registry]

The objective of the SAMISEN study is to assess the performance and safety of diagnostic and therapeutic procedures with the newly designed Olympus Motorized Spiral Enteroscope (PowerSpiral).

NCT ID: NCT03953196 Completed - Healthy Clinical Trials

A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy Participants

Start date: April 8, 2019
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to characterize the immune response in vivo using approved vaccines and antigen challenges, as well as a skin wounding challenge to stimulate the immune system.

NCT ID: NCT03950440 Completed - Clinical trials for Aortic Valve Stenosis

Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement

IPOD-AV
Start date: September 23, 2018
Phase:
Study type: Observational

Our primary aim in this observational study is to identify the incidence of POD in the first five postoperative days by using the 3-minute Diagnostic confusion assessment method (3D-CAM), the derived version for intensive care unit (CAM-ICU) or nurse reports in patients undergoing different techniques of aortic valve replacement. Patients are followed 5 days postoperative with the 3D-CAM or until resolution of POD. Six months postoperatively, a follow-up by phone is planned for activity of daily living (ADL).

NCT ID: NCT03948958 Completed - Cystic Fibrosis Clinical Trials

PREMO Study: to Investigate Port REMoval Outcomes

PREMO
Start date: June 28, 2019
Phase: N/A
Study type: Interventional

A Totally Implantable Venous Access Device (TIVAD) that is no longer in use for intravenous therapy, should be flushed at established intervals to promote and maintain patency. No consensus has been established regarding the optimal duration of the interval between 2 maintenance sessions. This exploratory study will focus on catheter status under the current 3-monthly flush regimen.

NCT ID: NCT03948503 Completed - Clinical trials for Ankle Sprain 2Nd Degree

Mulligan Concept in the Treatment of Ankle Sprains

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

Aim of the study is to establish the efficiency of the mulligan concept vs a sham group (who will also serve as control). Patient with an subacute ankle sprains will be assess following the mulligan concept and then randomized in two groups: Mobilization with movement (MWM) group and Sham group. MWM group will receive 3 sets of 10 repetitions of treatment (i.e. passive accessory glide during an active dorsiflexion) while the sham treatment will do 3 sets of 10 active dorsiflexion with the hand of the Physiotherapist only apply on the skin. 3 sessions with 4 days apart will take place. outcomes will be measure before and after every sessions.