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NCT ID: NCT00281593 Completed - Hypertension Clinical Trials

Telmisartan (Micardis) and Ramipril (Altace) - Factorial Design Study for the Treatment of Hypertension

Start date: April 2006
Phase: Phase 3
Study type: Interventional

To identify dose combinations of telmisartan and ramipril that are more effective in reducing diastolic blood pressure than each of the respective monotherapies in patients with Stage I or II hypertension.

NCT ID: NCT00281580 Completed - Hypertension Clinical Trials

Telmisartan (Micardis) and Amlodipine (Norvasc) - Factorial Design Study for the Treatment of Hypertension

Start date: April 2006
Phase: Phase 3
Study type: Interventional

To demonstrate that Micardis and Norvasc when used together are more effective at lowering blood pre ssure.

NCT ID: NCT00281554 Completed - Atrial Fibrillation Clinical Trials

Study of RSD1235 to Evaluate Safety in Patients With Atrial Fibrillation

ACT 4
Start date: October 2005
Phase: Phase 3
Study type: Interventional

This study is designed to determine the safety of RSD1235 in patients with atrial fibrillation.

NCT ID: NCT00279201 Completed - Clinical trials for Diabetes Mellitus, Type 2

The DURABLE Trial: Evaluating the Durability of Starter Insulin Regimens in Patients With Type 2 Diabetes (IOOV)

IOOV
Start date: December 2005
Phase: Phase 4
Study type: Interventional

This study will compare insulin lispro low mixture [LM] and insulin glargine both in combination with the patient's oral diabetes medicines, for their ability to control blood sugar in patients with type 2 diabetes and compare insulin lispro LM to insulin glargine with regard to the length of time that the overall blood sugar can be controlled. This study will also determine whether the safety of insulin lispro LM and any side effects that might be associated with it are different from those observed with insulin glargine, both in combination with the patient's oral diabetes medications. The addendum study (Intensification Addendum) will compare how different insulin treatments work to control blood sugar in patients whose diabetes could not be controlled by either insulin lispro LM or insulin glargine.

NCT ID: NCT00277810 Completed - Alzheimer Disease Clinical Trials

Study Evaluating the Safety, Tolerability, and Efficacy of Lecozotan SR in Outpatients With Alzheimer's Disease

Start date: March 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the study is to determine the safety, tolerability, and efficacy of 3 doses of lecozotan in combination with a cholinesterase inhibitor in patients with mild to moderate Alzheimer's disease (AD).

NCT ID: NCT00276757 Completed - Clinical trials for Childhood Langerhans Cell Histiocytosis

Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis

Start date: April 2001
Phase: N/A
Study type: Interventional

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of Langerhans cell histiocytosis, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may be an effective treatment for Langerhans cell histiocytosis. PURPOSE: This randomized clinical trial is studying combination chemotherapy to see how well it works in treating young patients with Langerhans cell histiocytosis.

NCT ID: NCT00274326 Completed - Clinical trials for Congestive Heart Failure

DILIPO (DILutIonal HyPOnatremia)

Start date: May 2005
Phase: Phase 3
Study type: Interventional

Primary: - To assess the efficacy of SR121463B in correcting hyponatremia in patients with dilutional hyponatremia other than SIADH or cirrhosis Secondary: - To assess the long-term efficacy of SR121463B in maintaining normonatremia in these patients - To assess the safety and tolerability of SR121463B

NCT ID: NCT00273546 Completed - Cancer Clinical Trials

Induction Chemotherapy Comparing Taxotere® Cisplatin and 5-Fluorouracil (TPF) With Standard Cisplatin and 5-Fluorouracil (PF) Followed by Chemoradiation in Locally Advanced Head and Neck Cancer

Start date: May 1999
Phase: Phase 3
Study type: Interventional

- 1.To compare overall survival after treatment with the test tri-therapy (TPF: docetaxel plus cisplatin and 5FU) or the control treatment (PF: cisplatin plus 5-FU) followed by chemoradiotherapy in patients with locally advanced SCCHN. - 2.The main secondary endpoint is progression free survival (PFS). The other secondary endpoints are to evaluate and compare improvement of local symptoms; time-to-treatment failure; quality of life; clinical complete response rate (CR and CR/PR); toxicity and to evaluate the relationship of tumor markers and response to therapy.

NCT ID: NCT00273039 Completed - Anxiety Disorders Clinical Trials

A Study Of A New Medicine (GW679769) For The Treatment Of Social Anxiety Disorder

Start date: August 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the safety and efficacy of GW679769 and paroxetine in subjects with Social Anxiety Disorder

NCT ID: NCT00272779 Completed - HIV Infections Clinical Trials

BMS-Reyataz Study in Treatment in Naive Subjects to Compare the Efficacy and Safety Between Boosted Reyataz and Kaletra When in Combination With Fixed Dose Truvada

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and antiviral effects of atazanavir (ATV) plus ritonavir (RTV) versus a combination drug of lopinavir (LPV) plus RTV. A combination drug containing tenofovir (TDF) and emtricitabine (FTC) will also be taken by participants in both arms.