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Cancer clinical trials

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NCT ID: NCT01272024 Completed - Cancer Clinical Trials

An Intervention to Improve Outcomes in Patients With Advanced Cancer

TEAMS
Start date: September 2009
Phase: Phase 3
Study type: Interventional

1.) To integrate discharge planning into an intervention provided by advanced practice nurses (APRNs)for patients with advanced cancer, 2.) To evaluate the effects of the intervention, and 3.) To explore the reach, adoption, and implementation of the intervention to facilitate the transition of patients from surgery/biopsy/chemotherapy to medical oncology in a comprehensive cancer center.

NCT ID: NCT01270906 Terminated - Cancer Clinical Trials

Safety of CHIR-258 (TKI258) in Advanced Solid Tumors

Start date: December 2003
Phase: Phase 1
Study type: Interventional

Phase I dose finding study in solid tumors.

NCT ID: NCT01269645 Completed - Cancer Clinical Trials

Facts and Attitudes About Clinical Trials

FACT
Start date: July 2009
Phase: N/A
Study type: Interventional

The primary objective of this project is to examine the impact of providing cancer patients with audiovisual information about clinical trials on attitudes towards clinical trial participation. It is hypothesized that patients provided these materials will have more favorable attitudes toward clinical trial participation compared to patients not provided these materials. Participants will be randomized to either: (1) an intervention condition in which they will be asked to view a short video and read an accompanying brochure about clinical trials developed by the investigative team; or (2) a control condition in which they will be asked to read the National Cancer Institute's brochure entitled "Taking Part in Cancer Treatment Research Studies." Self-report data will be collected at two timepoints: 1) in person following study enrollment, but before receipt of material related to intervention assignment (baseline/Time 1), and 2) by telephone interview between 7 and 28 days following study enrollment (follow-up/Time 2). In addition, data will also be collected from medical records six weeks after study enrollment.

NCT ID: NCT01268293 Completed - Cancer Clinical Trials

A Study of E7080 in Subjects With Solid Tumor

Start date: February 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the tolerability and safety of E7080 up to 24 mg when administered orally on a once daily continuous dose schedule in cycles (4 weeks as 1 cycle) in subjects with solid tumors

NCT ID: NCT01268163 Completed - Cancer Clinical Trials

The Pharmacokinetics and Safety Characteristics of Docetaxel in Patients With Cancer

Start date: August 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the pharmacokinetic and safety characteristics of European Taxotere® and American Taxotere® with Hospira Docetaxel injection in patients with cancer.

NCT ID: NCT01264887 Terminated - Pain Clinical Trials

Tapentadol in Chronic Malignant Tumour Related Pain

Start date: March 2011
Phase: Phase 3
Study type: Interventional

The purpose of this trial is the characterization of the long term safety profile and long-term dose requirements of tapentadol PR (prolonged release) in patients with malignant tumor-related pain. In the United States the prolonged-release formulation is also referred to as the extended-release formulation.

NCT ID: NCT01262963 Completed - Cancer Clinical Trials

An Absorption, Distribution, Metabolism and Excretion (ADME) Study of Single Oral Dose [14C] GSK2118436 in Subjects With BRAF Mutant Solid Tumors

Start date: January 26, 2011
Phase: Phase 1
Study type: Interventional

The study is a Phase 1, open-label study designed to characterize the absorption, distribution, metabolism and excretion of GSK2118436 following administration of a single oral 14C labeled dose of GSK2118436 as a suspension in subjects with BRAF mutation positive tumors.

NCT ID: NCT01262235 Completed - Cancer Clinical Trials

A Dose Finding Study of TKM-080301 Infusion in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients

Start date: December 2010
Phase: Phase 1/Phase 2
Study type: Interventional

This study will be a Phase I/II, open-label, non-randomized, dose-finding trial conducted at multiple clinical centers. The study is designed to determine the safety, tolerability and PK of TKM-080301 in adult patients with solid tumors or lymphomas that are refractory to standard therapy or for whom there is no standard therapy. After the determination of the maximum tolerated dose this dose will be utilized in an expansion cohort or subjects with refractory neuroendocrine tumors (NET) or adrenocortical carcinoma (ACC) tumors.

NCT ID: NCT01254929 Completed - Cancer Clinical Trials

F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases

Start date: December 2010
Phase:
Study type: Observational

The purpose of this study is to compare 18F-Fluoride PET bone scans to traditional 99mTc-MDP bone scan to determine if one is better for diagnosing bone metastases.

NCT ID: NCT01253720 Completed - Obesity Clinical Trials

PACE CALL: Weight Loss Study for Childhood Leukemia Survivors

Start date: June 2008
Phase: N/A
Study type: Interventional

UC San Diego researchers conducted a study to develop and evaluate an internet and text message based weight loss study for childhood acute lymphoblastic leukemia (ALL) survivors. We hypothesized that those study participants randomized to the intervention will demonstrate greater reduction in BMI-z score as compared to the control group.