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Cancer clinical trials

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NCT ID: NCT03403049 Recruiting - Cancer Clinical Trials

Carbon Ion Radiation Therapy for Locally Advanced Pancreatic Cancer

Start date: April 2016
Phase: Phase 1
Study type: Interventional

This is a phase I trial to determine the maximum tolerated dose of carbon ion radiotherapy for the treatment of locally advanced, unresectable, pancreatic cancer.

NCT ID: NCT03400514 Recruiting - Cancer Clinical Trials

Clinical Concordance Study Between Watson for Oncology and Clinician Practice

W001
Start date: April 12, 2017
Phase: N/A
Study type: Observational

At present, Watson for Oncology has been applied in 14 countries worldwide, including China, the United States, Holland, Thailand, India, Korea, Poland, Slovakia and Bangladesh. In a double-blind study involving 362 patients in India, treatment recommendations from Watson for Oncology (WFO) performed a high degree of consistency with their multidisciplinary tumor board. The investigators would recruit cancer patients diagnosed as lung cancer, breast cancer, gastric cancer, colon cancer, rectal cancer,cervical cancer or ovarian cancer according to the criteria of Watson for Oncology ,using the updated version of Watson for Oncology to explore the concordance of therapeutic regimen between WFO and physicians in the Affiliated Hospital of Qingdao University.

NCT ID: NCT03400332 Not yet recruiting - Cancer Clinical Trials

An Investigational Immuno-Therapy Study of Experimental Medication BMS-986253 Given in Combination With Nivolumab in Patients With Advanced Cancers

Start date: January 17, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate experimental medication BMS-986253 in combination with Nivolumab in patients with advanced cancers.

NCT ID: NCT03396510 Not yet recruiting - Cancer Clinical Trials

Electronic Symptom Monitoring Intervention for Hospitalized Patients With Cancer

Start date: January 31, 2018
Phase: N/A
Study type: Interventional

This research study is evaluating a new way to deliver oncology care for patients with cancer

NCT ID: NCT03396211 Recruiting - Cancer Clinical Trials

Study to Evaluate Apatinib Plus Nivolumab in Patients With Unresectable or Metastatic Cancer

Start date: December 22, 2017
Phase: Phase 1
Study type: Interventional

This is an open-labeled, single-center, Phase I study to evaluate the safety, tolerability, and efficacy of adding apatinib to ongoing nivolumab treatment in patients with unresectable or metastatic cancer. Approximately 9-18 subjects in Phase I dose escalation phase and up to 12 additional subjects in Part II expansion phase. Total study duration will be approximately 12 months: 6 months of recruitment plus 6 months of treatment.

NCT ID: NCT03394859 Enrolling by invitation - Diabetes Clinical Trials

Electronic Medical Records and Genomics (eMERGE) Phase III

eMERGE
Start date: September 1, 2015
Phase: N/A
Study type: Observational

The Electronic Medical Records and Genomics (eMERGE) Network is in its third phase and during this time is enrolling and sequencing 25,000 individuals on a custom sequencing panel of clinically relevant, actionable genes. The genetic results will be returned to participants and outcomes tracked through the electronic health records.

NCT ID: NCT03393858 Recruiting - Cancer Clinical Trials

Combination of Immunotherapy and Hyperthermia in Advanced Malignant Mesothelioma

Start date: December 1, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the clinical efficacy and toxicity of anti-PD-1 monoclonal antibody plus autologous dendritic cells-cytokine induced killer cell (DC-CIK) immunotherapy combined with hyperthermia in advanced malignant mesothelioma patients.Furthermore,to characterize response to therapy,the investigators intent to explore the predictive biomarker for this regimen.

NCT ID: NCT03393351 Not yet recruiting - Cancer Clinical Trials

Implementation of Shared Decision-Making in Cancer Care

PREPARED
Start date: March 2018
Phase: N/A
Study type: Interventional

This study aims to evaluate a theoretically and empirically grounded implementation program designed to foster shared decision-making in routine cancer care. The intervention program consists of several components (e.g. training for health care professionals, patient empowerment strategies) that will be rolled out in three clinics at a comprehensive cancer center in Germany.

NCT ID: NCT03391115 Enrolling by invitation - Cancer Clinical Trials

Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness

Start date: November 15, 2017
Phase: N/A
Study type: Observational

The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting illnesses. Eliciting personal experiences is an effective way for patients to communicate their cultural values and beliefs. This study will assess how to integrate the patients' personal experience narratives into the electronic health record (EHR). The primary hypothesis is that the implementation of a patient-centered intervention to elicit personal experiences that are included in the EHR will improve patient-provider communication and patients' QoL.

NCT ID: NCT03390816 Recruiting - Cancer Clinical Trials

Nutritional Status Assessment in the Elderly Suffering From Cancer : a National Cross-UCOG Survey

NutriAgeCancer
Start date: November 2, 2017
Phase: N/A
Study type: Observational

Protein-energy malnutrition (PEM) is a frequent condition in patients suffering from cancer, especially the elderly. According to some studies, this malnutrition has important consequences in this population, by increasing the risk of treatment toxicities, premature interruption of chemotherapy, mortality and risks of complications. Identifying cases of malnutrition is an objective pursued by the National Nutrition and Health Programme and an important task of the "Unités de Coordination en Oncogériatrie". The main goal of this study is to assess the loss of weight over the 6 month-period preceding the cancer treatment, regardless of kind (chemotherapy, targeted therapy, hormone therapy, immunotherapy, radiation therapy, surgery, comfort care), in the elderly suffering from cancer.