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Cancer clinical trials

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NCT ID: NCT03452774 Recruiting - Breast Cancer Clinical Trials

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Start date: January 1, 2018
Phase: N/A
Study type: Observational [Patient Registry]

International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical trial enrollment (CTE), as well as the financial impact, and potential outcomes of the intervention.

NCT ID: NCT03449511 Not yet recruiting - Cancer Clinical Trials

Aromatherapy for Integrated Cancer Care

Start date: March 24, 2018
Phase: N/A
Study type: Interventional

The purpose of this clinical trial is to determine the feasibility and effectiveness of aromatherapy in relief of commonly reported symptoms in cancer patients undergoing chemotherapy. Aromatherapy is a noninvasive, minimal risk intervention that could potentially alleviate the severity of treatment-related symptoms. This study will evaluate the ability of three aromatherapy scents (ginger, lavender, orange) to reduce the severity of seven chemotherapy-induced symptoms (nausea, vomiting, pain, anxiety/distress, fatigue, sleep difficulties, and lack of appetite). As part of the study, the participants will be asked to use an aromatherapy inhaler, which resembles a lipstick container, during three chemotherapy cycles. The participants will use the aromatherapy inhaler for 7 consecutive days. The investigators will ask the participants questions regarding demographics, clinical information, current severity of symptoms, and current methods of symptom management. The participants will rate the severity of seven different symptoms from 0 to 10 each day the aromatherapy inhaler during each of the three chemotherapy cycles (i.e., 7 consecutive days during each chemotherapy cycle). At the end of the study, the participants will be asked about his/her satisfaction with the aromatherapy used during the study. All of these measurements will provide a better understanding of the effectiveness of aromatherapy for symptom management.

NCT ID: NCT03447470 Recruiting - Cancer Clinical Trials

Study to Evaluate the Safety and Tolerability of RXC004 in Advanced Malignancies

Start date: February 5, 2018
Phase: Phase 1
Study type: Interventional

The purpose of Part A of this study is to determine the safety and tolerability of RXC004 in patients with advanced malignancies. In order to define the doses and schedules for further clinical evaluation.

NCT ID: NCT03447145 Recruiting - Cancer Clinical Trials

A New Drug Used for Advanced Cancer

Start date: December 26, 2017
Phase: Phase 1
Study type: Interventional

To identify the safety and tolerance of TQ-B3203.

NCT ID: NCT03446105 Recruiting - Cancer Clinical Trials

Promoting Quality of Life Among Young Adult Cancer Survivors

Start date: February 9, 2017
Phase: N/A
Study type: Interventional

This study expands on a prior pilot study to refine the intervention messaging to focus on goal-oriented thinking, include a coach, and extend the intervention to a larger sample of young adult cancer survivors (aged 18-39 years) recruited from two National Cancer Institute (NCI)-designated cancer centers (Emory's Winship Cancer Institute in Atlanta; University of Kentucky's Markey Cancer Center in Lexington). Participants will be randomly assigned (stratified by age and sex) to one of the 8-week treatment conditions in a 2:1 ratio (2 to intervention: 1 to attention control).

NCT ID: NCT03446092 Not yet recruiting - Cancer Clinical Trials

Mindfulness for People With Incurable Cancer

Start date: June 2018
Phase: N/A
Study type: Interventional

The study will investigate whether a mindfulness course can help people with incurable cancer who are seen by oncologists in a particular National Health Service Hospital Trust in the United Kingdom.

NCT ID: NCT03443635 Recruiting - Obesity Clinical Trials

Cooking for Health Optimization With Patients

Start date: February 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Cooking for Health Optimization with Patients (CHOP) is the first known multi-site prospective cohort study with a nested Bayesian adaptive randomized trial in the preventive cardiology field of culinary medicine. It is also the first known longitudinal study to assess the impact of hands-on cooking and nutrition education on patient outcomes, with those classes taught by medical students and other future and current medical professionals who have first been trained in those classes on how to integrate diet and lifestyle counseling of patients with their respective scopes of clinical practice. CHOP is the primary research study of the world's first known medical school based teaching kitchen, The Goldring Center for Culinary Medicine at Tulane University School of Medicine. Medical trainees and professionals are followed in this study long-term to understand how the classes impact their competencies in patient counseling, attitudes about the counseling, and their own diets. Patients who consent to being randomized to these classes compared to standard of care are studied within the nested Bayesian adaptive randomized trial to understand how the classes impact their health outcomes, clinical and food costs, and the costs of health systems caring for these patient populations. CHOP is designed as a pragmatic population health trial to hopefully improve healthcare effectiveness, equity, and cost by establishing an evidence-based, scalable, sustainable model of healthcare intervention targeting the social determinants of health, while complementing the pharmacological and/or surgical management of patients.

NCT ID: NCT03441100 Not yet recruiting - Cancer Clinical Trials

TCR-engineered T Cells in NSCLC and HCC Patients

Start date: March 2018
Phase: Phase 1
Study type: Interventional

The study purpose is to establish the safety and tolerability of IMA202 product in patients with certain solid tumors.

NCT ID: NCT03438201 Not yet recruiting - Cancer Clinical Trials

Protein Intake Associated With Physical Activity Related to Specific Outcomes

Start date: April 4, 2018
Phase: N/A
Study type: Interventional

This is a Randomized Controlled Trial . The purpose of this study is to assess the hypothesis that whether a high protein diet combined with a physical activity protocol in surgical cancer patients admitted to the ICU in the post operative period is associated with better physical function at the hospital discharge as well as a better quality of life.

NCT ID: NCT03436290 Enrolling by invitation - Cancer Clinical Trials

Surgery for Cancer With Option of Palliative Care Expert

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

Frequently people diagnosed with cancer experience physical and emotional symptoms during the course of their disease. These symptoms can be very distressing to both the patient and the family members. The study doctor wants to know if the introduction of a team of clinicians that specialize in the lessening of many of these distressing symptoms may improve your overall care. This team of clinicians is called the palliative care team and they focus on ways to improve your pain and other symptom management (i.e. shortness of breath, fatigue, anxiety, etc.) and to assist you and your family in coping with the emotional, social, and spiritual issues associated with your diagnosis. The team consists of physicians, advanced practice nurses, case managers, and nurses who have been specially trained in the care of patients facing serious illness. This research study is being done because although many people with cancer receive palliative care late in the course of their illness, the study team thinks palliative care may be more useful when it is started earlier and in this case before surgery. The main purpose of this study is to compare two types of care -usual surgery and cancer care and usual surgery and cancer care with comprehensive palliative care services to see which is better for improving the experience of patients and families with cancer.