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NCT ID: NCT02094807 Withdrawn - Pain Clinical Trials

Pain as Indication for Operative Treatment of Traumatic Rib Fractures

potf
Start date: April 2014
Phase: N/A
Study type: Interventional

The purpose of this prospective randomized controlled study is to determine whether acute and chronic pain in patients who suffer multiple traumatic rib fractures is decreased after surgical management as compared to conservative management.

NCT ID: NCT02099604 Withdrawn - Chronic Hepatitis C Clinical Trials

Efficacy and Safety of the Combination Vitamin D With Standard of Care in Egyptian Patients With Untreated Chronic Hepatitis C

ViZIR
Start date: April 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to show the superiority of a 4 weeks lead-in phase of Vitamin D followed by a 48 weeks combination of Vitamin D with PEG-IFN plus RBV in comparison with standard PEG-IFN + RBV in untreated Egyptian patients with chronic hepatitis C, on the sustained virological response (SVR) at 3 months after end of treatment (week 60).

NCT ID: NCT02100527 Withdrawn - Acne Vulgaris Clinical Trials

Study Of Safety, Tolerability And Effects Of PF-05175157 In Adults With Moderate To Severe Acne Vulgaris

Start date: April 2014
Phase: Phase 2
Study type: Interventional

This is a 6 week study to characterize the safety, tolerability and effects of PF-05175157 administered for 6 weeks in subjects with moderate to severe acne vulgaris.

NCT ID: NCT02101177 Withdrawn - Chronic Hepatitis C Clinical Trials

Evaluation of the National Treatment Program of Hepatitis C in Egypt

eNTC
Start date: April 2014
Phase: N/A
Study type: Observational

The aim of the study is to analyse data coming from two treatment centres of the National Treatment Program Centres of hepatitis C in Egypt

NCT ID: NCT02102438 Withdrawn - Breast Cancer Clinical Trials

Chemotherapy for Elderly Patients Diagnosed With Localized HER2 Positive Breast Cancer

Start date: April 2014
Phase: N/A
Study type: Interventional

There is major concern regarding chemotherapy related toxicity in the group of women older than 65 years old diagnosed with human epidermal growth factor receptor 2 (HER2) positive breast cancer (BC). Nevertheless, these patients are at a particularly high risk of breast cancer recurrence and death. Of note, older patients may experience higher risk for Trastuzumabe related cardiotoxicity, especially when this agent is combined with an anthracycline. Recent studies have shown extremely favourable outcomes in early HER2+ BC patients treated with a combination of paclitaxel and trastuzumab, omitting anthracyclines from treatment. Investigators sought to investigate safety and outcome data on a cohort of elderly patients treated with weekly paclitaxel combined with carboplatin and trastuzumab.

NCT ID: NCT02103881 Withdrawn - Agitation Clinical Trials

Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital

Start date: April 2014
Phase: Phase 4
Study type: Interventional

This research study is being done to find out if one of two drugs, ketamine or haloperidol, is better for treating agitation. Agitation is a state of extreme emotional disturbance where patients can become physically aggressive or violent, endangering themselves and those who are caring for them. Often chemical substances or severe mental illness is involved in this level of agitation. Specifically, the investigators are interested in studying agitation that is treated in the prehospital setting by paramedics. This study's hypothesis is that ketamine is superior to haloperidol for treatment of agitation in the prehospital environment.

NCT ID: NCT02103946 Withdrawn - Breast Cancer Clinical Trials

Serratus Anterior Plane Block Versus Paravertebral Block for Postmastectomy Analgesia

SAM
Start date: April 2014
Phase: N/A
Study type: Interventional

ًًًُُُُThe investigators are testing the efficacy of a new novel technique; serratus anterior plane block, for preventing postoperative pain after breast surgery for cancer. This block will be compared with the well-established paravertebral block.

NCT ID: NCT02106871 Withdrawn - Pancreatic Cancer Clinical Trials

Study of Sildenafil as a Therapy for Fatigue in Pancreatic Cancer

PCC
Start date: April 2014
Phase: Phase 1
Study type: Interventional

Investigation of the effects of daily sildenafil on patients with pancreatic or cholangiocarcinoma cancer undergoing treatment.

NCT ID: NCT02107924 Withdrawn - Infection Clinical Trials

Use of Antibiotic Carrier in Acute Periprosthetic Infections (APPI) of Total Knee Replacements

Start date: April 2014
Phase: N/A
Study type: Observational

The purpose of the study is to gather information on the use of Stimulan, the surgery, and anitbiotics to whetether the APPI has decreased or shown improvement when compared to study participants who did not receive Stimulan during their revision total knee replacement surgery.

NCT ID: NCT02108613 Withdrawn - Prostate Cancer Clinical Trials

Living Well on Androgen Deprivation Therapy

Start date: April 2014
Phase: N/A
Study type: Interventional

Approximately half of men treated for prostate cancer will be offered hormone deprivation therapy during their cancer experience. The secondary effects of this treatment can result in osteoporosis, cardiovascular disease, stroke, diabetes, and diminished sexual health. To promote healthy lifestyle choices for couples and maintain their intimacy and emotional health we propose the Living Well, an innovative program that combines nutrition, physical activity, and sexual health initiatives in one integrated service. This project will be piloted at the Vancouver Island Centre with an expected 100 patients over 1 year. Over a six month period both the experimental and control groups will have access to a workbook (designed for men with prostate cancer and on hormone deprivation therapy) and sexual health counseling. The experimental group will also have access to an exercise and a nutritional program and support by volunteers to keep motivated. Assessment will look at quality of life, physical factors, and biomarkers associated with secondary disease.