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Breast Cancer clinical trials

View clinical trials related to Breast Cancer.

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NCT ID: NCT03542175 Active, not recruiting - Breast Cancer Clinical Trials

A Study of Rucaparib Administered With Radiation in Patients With Triple Negative Breast Cancer With an Incomplete Response Following Chemotherapy

Start date: May 23, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to test the safety of a study drug called Rucaparib, administered in combination with the type of radiation therapy that is usually given to women with your form of breast cancer.

NCT ID: NCT03529565 Active, not recruiting - Bone Pain Clinical Trials

Histamine and Bone Pain Association in Participants With Breast Cancer Metastatic in the Bone

Start date: January 31, 2019
Phase:
Study type: Observational

This trial studies histamine and bone pain association in participants with breast cancer that has spread to the bone. Studying histamine levels in samples of blood from participants with breast cancer in the laboratory may help doctors learn more about reducing cancer bone pain and preventing further bone metastasis.

NCT ID: NCT03529110 Active, not recruiting - Breast Cancer Clinical Trials

DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]

Start date: August 9, 2018
Phase: Phase 3
Study type: Interventional

This study is designed to compare the anti-tumor activity as well as the safety and efficacy of DS-8201a versus T-DM1 in HER2-positive, unresectable and/or metastatic breast cancer subjects previously treated with trastuzumab and taxane.

NCT ID: NCT03523585 Active, not recruiting - Breast Cancer Clinical Trials

DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]

Start date: August 1, 2018
Phase: Phase 3
Study type: Interventional

This study will compare DS 8201a to standard treatment. Participants must have HER2 breast cancer that has been treated before. Their cancer: - cannot be removed by an operation - has spread to other parts of the body

NCT ID: NCT03523572 Active, not recruiting - Breast Cancer Clinical Trials

Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer

Start date: June 20, 2018
Phase: Phase 1
Study type: Interventional

This is a study of trastuzumab deruxtecan, which was approved by the FDA (in December 2019) for the treatment of HER2-positive unresectable or metastatic breast cancer following two or more prior anti-HER2 based regimens. Participants will receive this study drug along with a cancer drug, an immune checkpoint inhibitor, anti-PD1, called nivolumab. The study will be done in two parts: - Part 1 is to identify the recommended dose to use for treatment. - Part 2 is to find out how well the combination works, and how safe and tolerable it is.

NCT ID: NCT03523546 Active, not recruiting - Breast Cancer Clinical Trials

Oncology Episode Payment Model in Hawaii

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The HMSA Cancer Episode Payment Model (CEM) is a payment model designed to test the effects of better care coordination on health outcomes and costs of care for Hawaii Medical Services Association (HMSA) members with cancer who receive chemotherapy.

NCT ID: NCT03518606 Active, not recruiting - Breast Cancer Clinical Trials

Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours

MOVIE
Start date: June 20, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase I/II national, multicentre, multiple cohort, prospective open-label, non-randomised and non-comparative study, to evaluate the safety and activity of metronomic oral vinorelbine associated with durvalumab + tremelimumab combination immunotherapy for the treatment of advanced solid tumours.

NCT ID: NCT03495115 Active, not recruiting - Breast Cancer Clinical Trials

Comparing Restriction Spectrum Imaging (RSI) to Conventional and Abbreviated Breast MRI for Breast Cancer Screening

Start date: April 18, 2018
Phase: N/A
Study type: Interventional

This study is looking at a breast cancer screening technique, restriction spectrum imaging (RSI), as a possible alternative to the breast Magnetic Resonance Imaging (MRI) used by most healthcare professionals. The technique involved in this study is: -Restriction Spectrum Imaging (RSI)

NCT ID: NCT03495011 Active, not recruiting - Clinical trials for Breast Cancer, Stage 0

MRI Characterization of Mammographically Detected DCIS

Start date: April 20, 2018
Phase:
Study type: Observational

This is a single institution, prospective observational clinical trial for women with mammographically identified calcifications that may represent ductal carcinoma in situ (DCIS). The purpose of this study is to determine whether quantitative, multiparametric breast MRI performed prior to surgical resection can biologically characterize this common pre-invasive malignancy, ductal carcinoma in situ (DCIS), which typically presents in asymptomatic women as suspicious calcifications on mammography.

NCT ID: NCT03483012 Active, not recruiting - Breast Cancer Clinical Trials

Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain Metastasis

Start date: May 1, 2018
Phase: Phase 2
Study type: Interventional

This research study is studying the combination of a drug called atezolizumab and a radiation procedure called stereotactic radiosurgery (SRS) as a possible treatment for triple-negative breast cancer that has spread to the brain. The interventions involved in this study are: - Atezolizumab - Stereotactic radiosurgery (SRS)