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Breast Cancer clinical trials

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NCT ID: NCT03250130 Recruiting - Breast Cancer Clinical Trials

Hypnosis for Patients Treated With Adjuvant Chemotherapy for Breast Cancer(HYPNOVAL)

Start date: June 2015
Phase: N/A
Study type: Interventional

The main objective is to assess the feasibility of an intervention based on medical Ericksonian hypnosis as a complementary therapy in patients treated with surgery after a diagnosis of breast cancer, followed by an indication of adjuvant chemotherapy and radiotherapy

NCT ID: NCT03248427 Recruiting - Breast Cancer Clinical Trials

Neadjuvant Multi-agent Chemotherapy or Letrozole Plus Ribociclib in Luminal B/HER2-negative Breast Cancer.

Start date: July 13, 2017
Phase: Phase 2
Study type: Interventional

CORALLEEN is a two-arm, randomized, multicentric study in postmenopausal women with primary HR+/HER2 negative Luminal B breast cancer that will explore if the combination of ribociclib with letrozole offers clinical benefit at least comparable to that of standard chemotherapy.

NCT ID: NCT03245788 Recruiting - Breast Cancer Clinical Trials

Effectiveness of Lay Navigators in Meeting Cancer Patients' Non-Clinical Needs: A Pilot Study

Start date: February 15, 2017
Phase: N/A
Study type: Interventional

The Stanford Cancer Center is undertaking a Transformation Initiative in order to improve the quality of care, make it more patient-centered and coordinated across the continuum of care. The newest innovation is to introduce lay navigators to specified high-need patients. The larger goal of the project is to assess whether lay navigators can address non-clinical patient needs in a timely fashion and appropriately connect them with their clinical team when warranted. It is expected that proactive interaction with patients will decrease patient anxiety/stress related to their cancer and facilitate higher patient engagement and improved management of physical, social,and emotional health. For the pilot project, the smaller goal is to understand: how lay navigator time is used; the types and frequency of issues brought up by patients; resources that patients are given or referred to; type and frequency of mode of contact with patients; and patients' acceptance of navigators based on refusal. An electronic intake form will be used to collect this information so that data can be analyzed regularly and informed change can be made to the navigator program as needed

NCT ID: NCT03243877 Recruiting - Breast Cancer Clinical Trials

Performance of MammoAlertâ„¢, Point of Care System, for the Screening of Breast Cancer in Women 18 Years of Age or Older

Start date: June 17, 2017
Phase: N/A
Study type: Observational

POC Medical Systems has developed a Point of Care system for the screening of breast cancer in the general population. Via a proprietary algorithm, the MammoAlertâ„¢ is expected to determine breast cancer's risk level for a subject by identifying the presence in plasma of known biomarkers. The present study aims to determine the Sensitivity and Specificity of the test in plasma samples of subjects of whom the status vis-à-vis breast cancer is known.

NCT ID: NCT03243786 Recruiting - Breast Cancer Clinical Trials

Stay on Track: A Study of Exercise Effects During Radiation

Start date: April 12, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the impact of a lifestyle intervention. The study will examine the Stay on Track program, dietary and activity patterns, body composition, biomarkers and quality of life in breast cancer patients undergoing radiation therapy.

NCT ID: NCT03239756 Recruiting - Breast Cancer Clinical Trials

Assessment of TK006 in Patients With Breast Cancer-related Bone Metastases

Start date: July 20, 2017
Phase: Phase 1
Study type: Interventional

This is a single-center, open-label, dose-escalating study to evaluate the safety, pharmacokinetics, immunogenicity, and preliminary efficacy of single and multiple subcutaneous injection TK006 in patients with breast cancer-related bone metastases.

NCT ID: NCT03235427 Recruiting - Breast Cancer Clinical Trials

The CAROLE (CArdiac Related Oncologic Late Effects) Study

Start date: June 27, 2017
Phase: N/A
Study type: Observational

CAROLE seeks to evaluate the relationship between chest Radiation Therapy and coronary artery disease. The purpose of CAROLE is to check the heart health of women who received breast cancer treatments in the past and protect them from future heart disease.

NCT ID: NCT03233334 Recruiting - Breast Cancer Clinical Trials

Purpose Project: Reclaiming Life Purpose After Breast Cancer (Feasibility Study)

Start date: August 1, 2017
Phase: N/A
Study type: Interventional

The Purpose Project intervention is an 8-session progressive structure that was developed based on theoretical and scientific evidence from psychology and occupational therapy. The goal of the intervention is to provide participants with information, tools, and support that help them move towards reclaiming a sense of self-grounded purpose in daily life. The study will use a convenience sample of women with breast cancer to evaluate the feasibility of the Purpose Project intervention in terms of demand/acceptability, implementation, and limited-efficacy testing. Findings will be used to inform a later study to evaluate the efficacy of the Purpose Project intervention.

NCT ID: NCT03229824 Recruiting - Breast Cancer Clinical Trials

Use of Clorhexidine Dressings to Reduce Surgical Site Infections in Breast Cancer Surgery. A Controlled Clinical Trial

Start date: October 3, 2016
Phase: N/A
Study type: Interventional

Surgical site infection (SSI) after breast and axillary surgery occurs more often than for other clean surgical procedures. Infection in the setting of sick woman could delay the adjuvant therapy and result increase morbidity and mortality. Also this increased costs associated with health care.Surgical drains have been noted as a potential source for surgical site infections. The primary aim of the study is to determine if chlorhexidine occlusive dressings applied to the intervention drain sites effectively decreases rates of bacterial colonization in drain fluid and drain tips compared to standard care.

NCT ID: NCT03225170 Recruiting - Breast Cancer Clinical Trials

Is it Feasible?: Self-Affirmation for Hereditary Breast and Ovarian Cancer Genetic Counseling

Start date: August 18, 2017
Phase: N/A
Study type: Interventional

Background: Some women with breast cancer and ovarian cancer are genetically predisposed to them. This is called hereditary breast and ovarian cancer (HBOC). The women have to make hard choices about tests and treatment. Researchers want to study the best way to guide them. A kind of writing exercise might help if it is done before genetic counseling. It is called a self-affirmation (SA) exercise. It may lead to better communication in the counseling and better behavioral outcomes. Objective: To test if an SA exercise done with HBOC genetic counseling could improve client communication and behavior. Eligibility: Adults ages 18-90 with an appointment at the HBOC clinic at St. Luke s Health System Adults ages 18-90 who are genetic counselors with breast and ovarian cancer clients Design: Appointment participants will be screened by phone. They will arrive 15 minutes early to their appointment. They will do a 10- to 15-minute survey and writing exercise. This includes questions about: If they have cancer If they have had or were offered genetic counseling Things that are important to them After the appointment, they will take a 10- to 15-minute follow-up survey. It can be in the office or online. It includes questions about how they felt about the writing exercise and their counseling. Counselor participants will take a 2- to 5-minute survey after sessions with clients in the study. This includes questions about how the client was in the session. They will take a 10- to 15-minute survey at the end of the study. It will be about their opinions of the writing exercise.