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Breast Cancer clinical trials

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NCT ID: NCT03384992 Enrolling by invitation - Breast Cancer Clinical Trials

Targeted eHealth Intervention to Reduce Fear of Recurrence Among Breast Cancer Survivors

FoRtitude
Start date: March 2014
Phase: N/A
Study type: Interventional

The FoRtitude trial aims to evaluate an eHealth intervention designed to teach breast cancer survivors strategies to manage anxiety about cancer recurrence. The eHealth intervention includes educational content and interactive tools, designed to teach coping strategies and/or inert content, depending on the study participant's randomization assignment. The FoRtitude study will examine whether three coping strategies (relaxation training, cognitive restructuring, worry practice) are more effective than general health-related content in reducing fear of cancer recurrence.

NCT ID: NCT03294330 Enrolling by invitation - Breast Cancer Clinical Trials

SPY-X: A Study to Assess the Feasibility of Using SPY Alone for Sentinel Node Localization for Melanoma or Breast Cancer

SPYX
Start date: October 11, 2017
Phase: Phase 3
Study type: Interventional

The objective of this study is to determine if fluorescence lymphangiography can be used alone to localize sentinel nodes in patients with melanoma or breast cancer. The hypothesis is that sentinel nodes can be identified using only indocyanine green (ICG) and fluorescence lymphangiography, without the need for technetium99 and a gamma probe.

NCT ID: NCT03136367 Enrolling by invitation - Breast Cancer Clinical Trials

What Matters Most: Choosing the Right Breast Cancer Surgery for You

Start date: September 18, 2017
Phase: N/A
Study type: Interventional

What Matters Most is a study that aims to determine how best to help women of lower socioeconomic status make high-quality decisions about early stage breast cancer treatments. What Matters Most will be comparing two decision aids used in the clinic visit to usual care (what normally happens in the clinic). The first decision aid (Option Grid) presents evidence-based information about lumpectomy and mastectomy in a tabular format using text only. The second decision aid (Picture Option Grid) presents evidence-based information about lumpectomy and mastectomy using pictures, pictographs and simplified text. What Matters Most aims to show that the interventions can reduce disparities in decision-making and treatment choice between women of high and low SES.

NCT ID: NCT03116035 Enrolling by invitation - Breast Cancer Clinical Trials

Impact of Pre-Operative Web-based Breast Cancer Information on the Quality of Patient Decision-Making

Start date: April 24, 2014
Phase: N/A
Study type: Interventional

This is a prospective randomized control trial to compare the impact of two different types of pre-operative web-based breast cancer information on the quality of patient decision making. Patients are emailed web-based information prior to the surgical consultation. Outcomes are assess at multiple time points: 1) prior to the surgical consultation, 2) immediately following the consultation.

NCT ID: NCT02980848 Enrolling by invitation - Breast Cancer Clinical Trials

Assessing Breast Density's Value in Imaging - A Comparative Effectiveness Study

BCSC-ADVANCE
Start date: September 2016
Phase: N/A
Study type: Observational [Patient Registry]

This Beast Cancer Surveillance Consortium (BCSC) ADVANCE study is a large, observational pragmatic comparative effectiveness research study using high-quality, prospectively collected data from BCSC registries to generate evidence on how breast density should be integrated into decision making around breast cancer screening and preoperative diagnostic work-up. We will augment existing BCSC registry infrastructure with additional prospective data collection and collection of patient reported outcomes (PROs), CISNET modeling of long-term screening outcomes, and qualitative data from focus groups with women represented in two aims.

NCT ID: NCT02955940 Enrolling by invitation - Breast Cancer Clinical Trials

An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

Start date: November 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to provide continued supply of ruxolitinib alone, ruxolitinib plus background cancer therapy, or background cancer therapy alone to subjects from an Incyte-sponsored study of ruxolitinib that has reached its study objectives or has been terminated. This study will also provide another mechanism for reporting adverse events related to study drug safety.

NCT ID: NCT02943265 Enrolling by invitation - Breast Cancer Clinical Trials

Care Coordination for Complex Cancer Survivors in an Integrated Safety Net System

Start date: September 18, 2017
Phase: N/A
Study type: Interventional

Nearly 70% of people living with cancer are "complex patients" with multiple chronic conditions who must deal not only with effects of their cancer but also continuing diseases such as diabetes, depression, hypertension, or heart disease. Care coordination strategies shown to be effective in improving outcomes for common medical conditions seen in primary care include: systematic transitions for patients to and from specialty care; intensive case management; and a team-based approach to comprehensive care. Despite an Institute of Medicine report suggesting these strategies as potential ways to improve care for cancer survivors, their implementation has not yet been evaluated for cancer survivors. Parkland Health and Hospital Systems will be implementing care coordinator strategies as part of as quality assurance/quality improvement activities, which Aim 2 and Aim 3 (research components) will evaluate. This protocol has been organized to reflect this distinction between the aims. The investigators expect no more than 1500 patients to be included in these study aims.

NCT ID: NCT02910986 Enrolling by invitation - Breast Cancer Clinical Trials

Latinas Learning About Density

Start date: September 2016
Phase: N/A
Study type: Interventional

This study will examine behavioral and psychological outcomes of breast density notification using a 3-group randomized design comparing usual written notification to two educationally enhanced approaches.

NCT ID: NCT02897934 Enrolling by invitation - Breast Cancer Clinical Trials

CWI and Discharge After Breast Cancer Surgery

Start date: August 2016
Phase: N/A
Study type: Observational

The objectives of this work are threefold: 1. To evaluate the analgesic efficacy of CWI in women discharged within 23 hours of major breast cancer surgery 2. To evaluate objective indices of patient recovery following anaesthesia and surgery in a 23 hour model of care 3. To evaluate patient satisfaction with their care pathway

NCT ID: NCT02831439 Enrolling by invitation - Breast Cancer Clinical Trials

A Statewide Intervention to Reduce Use of Unproven or Ineffective Breast Cancer Care

Start date: September 2014
Phase: N/A
Study type: Interventional

The goal of this project is to examine the effectiveness and potential cost savings of two organizational interventions aimed at reducing the use of ineffective or unproven care among women with incident breast cancer.