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Breast Cancer clinical trials

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NCT ID: NCT03919682 Completed - Breast Cancer Clinical Trials

Promoting Early Detection of Breast Cancer in Rural Rwanda: Impact of Community Health Worker and Nurse Training

Start date: April 18, 2015
Phase: N/A
Study type: Interventional

This project proposes a pilot intervention in Burera District to train rural Rwandan community health workers (CHWs) in breast awareness, and to train primary care nurses at rural health centers in the assessment and management of breast complaints, with a focus on when patients must be urgently referred for more advanced evaluation. The project will randomize health centers to receive the intervention and will evaluate the impact of these trainings on nurse and CHW knowledge and skills. In order to help Rwanda prepare for national early detection efforts, the investigators will also assess the impact of these trainings on patient volume at the health center level, and visits and further diagnostic testing at the district hospital level. The investigators will also examine the impact on the length of diagnostic delays experienced by patients with a breast problem. Among those patients diagnosed with breast cancer, the investigators will also assess their stage at diagnosis.

NCT ID: NCT03889171 Completed - Breast Cancer Clinical Trials

Comparison to Psychological, Medical and Emotional Influencing Communication and Achievement Factors to Oncogenetics Tests

Start date: August 2012
Study type: Observational

The purpose of the study was to analyze the psychological and emotional determinants of domestic dissemination of information about genetic risk of cancer and to compare the level of diffusion syndromes in breast/ ovarian cancer ( BRCA1 / BRCA2) and colon/endometrial ( HNPCC )

NCT ID: NCT03888677 Completed - Breast Cancer Clinical Trials

Dose-adjusted Adjuvant FEC Compared to Standard FEC for Breast Cancer

Start date: February 2001
Phase: Phase 3
Study type: Interventional

This is an open randomized phase III study. The primary objective of this study is to compare FEC adjuvant chemotherapy in operable breast cancer given either as fixed doses calculated according to the patients surface area or with doses adjusted according to leukopenia after course one in order to achieve hematological equitoxicity. The main aim of the study is to test whether chemotherapy dosage aimed at hematological equitoxicity will improve the effect of adjuvant chemotherapy.

NCT ID: NCT03887130 Completed - Breast Cancer Clinical Trials

Study of Oral Vinorelbine Plus Capecitabine Versus Taxane-gemcitabine Combinations as 1st Line Chemotherapy in Metastatic Breast Cancer

Start date: March 2006
Phase: Phase 2
Study type: Interventional

The aim of this international open-label randomized phase II trial is to evaluate the efficacy and safety of an all-oral combination and two all-intravenous combinations as first-line therapy for HER2-negative mBC patients.

NCT ID: NCT03868865 Completed - Breast Cancer Clinical Trials

Effects of an Integrative Day-care Clinic Program for Breast Cancer Patients During Chemotherapy

Start date: August 7, 2012
Phase: N/A
Study type: Interventional

The aim of the study was to evaluate a new integrative day-care clinic concept for breast cancer patients receiving chemotherapy. This is an explorative pilot study. Therefore, all outcomes are analyzed exploratively.

NCT ID: NCT03858738 Completed - Breast Cancer Clinical Trials

A Pilot Study on Use of Liquid Crystal Contact Thermography to Detect Early Breast Cancer

Start date: April 20, 2015
Study type: Observational

The study was a multicentre, observational, cross-sectional, open and monitored trial involving 274 females who were subject to an examination using liquid crystal contact thermography device as a complementary tool to standard diagnostic imaging procedures of the breast glands. The study was conducted in specialist outpatient clinics. Patients were eligible to participate in the study upon signing the informed consent form. There was no follow up after the thermographic examination. The study will comprise of a single registration of thermographic images of the breasts which will be subjected to automatic and expert analysis by radiologists.

NCT ID: NCT03846999 Completed - Breast Cancer Clinical Trials

Comorbidities and Health Care Services Utilisation Among Long-term Breast Cancer Survivors

Start date: January 1, 2012
Study type: Observational

The increased likelihood of survival can be explained by numerous factors, such as improvements in breast cancer screening and advances in diagnosis and treatment and aging. This phenomenon is associated with comorbidity due to cancer treatment and external factors like aging or lifestyle. Little is known about how these women follow-up their disease, their pattern of use of health resources and their met and unmet needs. Studying the health needs of these women is a cancer-related priority for Cancer Organizations.The project is aimed at: 1) Describing the comorbidities and patterns of use of primary and specialized care in women who have survived a breast cancer for at least five years; 2) Comparing the comorbidities and patterns of use of long time breast cancer survivors with women without a cancer diagnosis; and 3) Estimating the use of resources in long time survivors of breast cancer adjusted for survival-time and comorbidities.

NCT ID: NCT03844685 Completed - Breast Cancer Clinical Trials

Red Clover and Lifestyle Changes to Contrast Menopausal Symptoms in Premenopausal Breast Cancer Patients Given Tamoxifen

Start date: July 5, 2012
Phase: Phase 2
Study type: Interventional

A prospective double-blind randomized trial of red clover extract (Promensil) vs placebo in surgically-treated premenopausal women with estrogen receptor-positive breast cancer taking tamoxifen

NCT ID: NCT03799757 Completed - Breast Cancer Clinical Trials

Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain

Start date: January 2016
Phase: Phase 4
Study type: Interventional

in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early postoperative period

NCT ID: NCT03788187 Completed - Breast Cancer Clinical Trials

Persistant Organics Pollutants in Breast Cancer.

Start date: August 2013
Phase: N/A
Study type: Interventional

Persistant Organics Pollutants (POP) accumulate in the adipose tissue (AT) and could modulate tumor progression as part of the microenvironment. The investigators tested the hypothesis that POPs exposure may be associated with breast cancer metastasis analyzing the concentrations of 46 POPs in both adipose tissue and serum samples from breast tumor patients (benign, malignant with and without lymph node metastasis)