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Breast Cancer clinical trials

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NCT ID: NCT03698942 Completed - Breast Cancer Clinical Trials

Delphinus SoftVue™ ROC Reader Study

DMT SV RRS
Start date: September 23, 2018
Phase:
Study type: Observational

The purpose of this multi‐reader, multi‐case (MRMC) reader study is to evaluate reader performance when SoftVue™ automated breast ultrasound and screening mammography are combined, compared to screening mammography alone, in women with dense breast parenchyma. This includes obtaining information that can be used to properly plan, design, and power future ROC reader studies. This reader study will include a minimum of 6 radiologist readers and an enriched sample of at least 100 breast screening or diagnostic cases to be selected from the library of images collected under Delphinus Protocol #DMT‐2015.001 (NCT03257839). The reader study image case set will be enriched with cancer cases.

NCT ID: NCT03652935 Completed - Breast Cancer Clinical Trials

Mindfulness, Breast Cancer and Psycho-Immune Dysregulation

Start date: September 15, 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the benefits of a Mindfulness Based Stress Reduction (MBSR) program for psycho-immune dysregulation in women newly diagnosed with breast cancer compared to women with breast cancer completing an attention control condition (health education classes). Women will be randomized to either the MBSR or health education classes. They will complete psychometric instruments evaluating psychological outcomes and will provide blood samples for immune outcomes. They will also provide saliva samples for cortisol diurnal rhythm determination. Measures will be done longitudinally pre and post MBSR or health education program. It is hypothesized that MBSR participants will exhibit improved psychological and immunological outcomes over time, as compared to women randomized to the health education classes.

NCT ID: NCT03615430 Completed - Breast Cancer Clinical Trials

Serratus Plane Block in Preventing Postoperative Pain of Mastectomy

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

A prospective, double-blinded randomized controlled, 1-year follow-up study was designed to compare the analgesic effect of serratus plane block (SPB) after breast cancer surgery. Women undergoing radical mastectomy were dIvided into Control group and SPB group. The postoperative acute pain was evaluated by numerical rating scale (NRS) and the effect of preventing chronic pain was assessed at 3, 6, 12 months after surgery by NRS.

NCT ID: NCT03612934 Completed - Breast Cancer Clinical Trials

The Impact of SPC on Advanced Breast Cancer Patients

Start date: May 1, 2015
Phase:
Study type: Observational

The aim of this prospective, observational study is the evaluation of the effectiveness of a 14-day Specialist Palliative Care therapy in participants with advanced breast cancer carried out in a stationary palliative care unit in Poland. The length of the entire study will be 36 months.

NCT ID: NCT03604939 Completed - Breast Cancer Clinical Trials

Improving Access to Control of Diseases for Women

IMPACD
Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the feasibility and acceptability of the model of delivering CHW-driven home-based comprehensive NCD control services aimed to prevent premature deaths from cardio-vascular diseases, stroke and breast, cervix and oral cancers in the hard-to-reach women.

NCT ID: NCT03581630 Completed - Breast Cancer Clinical Trials

Effects of Mediterranean Diet and Naltrexone/Bupropion Treatment in Obese Breast Cancer Patients

Start date: July 29, 2017
Phase: N/A
Study type: Interventional

Obesity among breast cancer survivors is known to be associated with recurrence and other co-morbidities. However, there have been no studies on weight reduction program combining diet and anti-obesity drug for obese breast cancer survivors. The purpose of this randomized clinical trial is to examine the effects of Mediterranean Diet and naltrexone/bupropion treatment on inflammation and metabolic risk factors in overweight or obese breast cancer patients after breast cancer treatment.

NCT ID: NCT03576521 Completed - Breast Cancer Clinical Trials

Evaluation of Ocoxin®-Viusid® in Breast Cancer

Start date: May 13, 2015
Phase: Phase 2
Study type: Interventional

The purpose is to determine the efficacy of the nutritional supplement Ocoxin-Viusid oral solution (OV) in the reduction of acute toxicity of Chemotherapy (CT) treatment with patients with breast carcinoma. A randomized, double-blind phase II clinical trial was designed, with a sample of 120 patients distributed in 2 arms: 60 patients will receive the CT treatment plus the OV, 60 will receive CT plus OV placebo. The OV / placebo will be administered before, during and 3 weeks after the conclusion of the CT. A better tolerance to the treatment is expected with the addition of the nutritional supplement.

NCT ID: NCT03575520 Completed - Breast Cancer Clinical Trials

Safety and Efficacy of Pegteograstim in Korean Breast Cancer Patients

Start date: June 7, 2016
Phase: Phase 2
Study type: Interventional

This is a prospective, single arm study, which is examining doxorubicin and cyclophosphamide (AC) once every 2 weeks with pegteograstim support in Korean early breast cancer.

NCT ID: NCT03546673 Completed - Breast Cancer Clinical Trials

Health Benefits of Expressive Writing: Study One

Komen
Start date: July 2009
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial (RCT) with the aim of determining the cultural sensitivity, feasibility, and effectiveness of an expressive writing intervention for Chinese breast cancer survivors.

NCT ID: NCT03546478 Completed - Breast Cancer Clinical Trials

99mTc Labelled Affibody SPECT/CT Imaging for Breast Cancer HER2 Characterization

Start date: June 24, 2015
Phase: Early Phase 1
Study type: Interventional

This is an open-label single photon emission tomography/computed tomography (SPECT/CT) study to investigate the diagnostic performance and evaluation efficacy of 99mTc-ABH2 in breast cancer patients. A single dose of 370±54 Mega-Becquerel (MBq)99mTc-ABH2 will be injected intravenously. Visual and semiquantitative method will be used to assess the SPECT/CT images.