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Breast Cancer clinical trials

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NCT ID: NCT03518268 Not yet recruiting - Breast Cancer Clinical Trials

Vivomixx for Prevention of Bone Loss in Women With Breast Cancer Treated With an Aromatase Inhibitor

Start date: May 2018
Phase: Phase 1/Phase 2
Study type: Interventional

This study evaluates the efficacy of the probiotic food supplement Vivomixx in the prevention of bone loss occurring in post menopausal women with breast cancer treated with an aromatase inhibitor. Half of the participants will receive Vivomixx while the other half will receive a placebo. The primary endpoint is to assess changes of bone turnover markers during the period of 6 months.

NCT ID: NCT03517332 Recruiting - Breast Cancer Clinical Trials

Circulating Tumor DNA Exposure in Peripheral Blood

Start date: January 1, 2015
Phase:
Study type: Observational

This is a prospective, multi-center, blinded feasibility study. The objective of this study is to test the feasibility of the detection of tumor DNA of a variety of tumors in peripheral blood using a novel process for the detection of circulating tumor DNA (ctDNA).

NCT ID: NCT03516253 Not yet recruiting - Breast Cancer Clinical Trials

Fish Oil and EPO in Breast Cancer

Start date: June 20, 2018
Phase: N/A
Study type: Interventional

Recent literature data suggest beneficial effects of dietary fats in patients with cancers, in particular polyunsaturated fatty acids (PUFAs). Fish oil and evening primrose oil provide a high amount of PUFAs and a desirable n-6/n-3 PUFAs ratio.

NCT ID: NCT03514121 Recruiting - Breast Cancer Clinical Trials

FPA150 in Patients With Advanced Solid Tumors

FPA150-001
Start date: March 27, 2018
Phase: Early Phase 1
Study type: Interventional

This is a multi-center study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of FPA150, an anti-B7H4 antibody in patients with advanced solid tumors. The Phase 1a, open-label, cohort will identify a recommended dose of FPA150 to use for Phase 1b.

NCT ID: NCT03511859 Recruiting - Breast Cancer Clinical Trials

Detecting Circulating Tumor Cells (CTCs) and Cell Free DNA (cfDNA) in Peripheral Blood of Breast Cancer (BC) Patients to Develop the Clinical Application for Early Detection and Diagnostics

Start date: November 16, 2017
Phase:
Study type: Observational

Utilization of circulating-tumor-cell (CTC) and cell free DNA (cfDNA) as novel and noninvasive tests for diagnosis confirmation, therapy selection, and cancer surveillance is a rapidly growing area of interest. In the wake of FDA approval of a liquid biopsy test, it is important for clinicians to acknowledge the obvious clinical utility of liquid biopsy for cancer management throughout the course of the disease.

NCT ID: NCT03511378 Recruiting - Breast Cancer Clinical Trials

Assessment of the Immunogenicity of Peg-filgrastim Versus Neulasta® as an Adjunct to Chemotherapy in Patients With Breast Cancer

Start date: March 6, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the immunogenicity of Peg-filgrastim versus Neulasta® as an adjunct to chemotherapy in patients with breast cancer

NCT ID: NCT03511079 Not yet recruiting - Breast Cancer Clinical Trials

Music as a Perioperative Therapy in Breast Cancer Patients

Start date: May 2018
Phase: N/A
Study type: Interventional

Music has often been used in hospitals as a therapy but there is a limited amount of research looking at how music actually affects the different molecules in the body, such as cortisol (a marker of stress). There is especially a lack of research in the context of surgery. The hope is that this study will show that music can be used to minimize some of the side effects related to breast surgery and improve the patient experience.

NCT ID: NCT03509090 Recruiting - Breast Cancer Clinical Trials

Evaluation of Analgesic Efficacy of Ultrasound-guided Erector Spinae Block in Segmental Mastectomy.

Start date: March 27, 2018
Phase: N/A
Study type: Interventional

Erector spinae plane block (ESPB) is a recently described block. Although there is still no consensus of its mechanism, the published case series seems to promise a new regional anesthesia technique for both chronic and acute pain. In this clinical trial, the postoperative analgesic effect of ESPB will be studied in patients underwent unilateral breast cancer surgery.

NCT ID: NCT03508011 Recruiting - Breast Cancer Clinical Trials

A Study of IMP4297 in Patients With Advanced Solid Tumors

Start date: August 23, 2017
Phase: Phase 1
Study type: Interventional

This is a Phase I, first-in-human, open-label, dose-escalation study of IMP4297 administered orally once every day to patients with advanced solid tumors for whom standard therapy either does not exist or has proven to be ineffective or intolerable. Patients with advanced breast cancer, ovarian cancer or prostate cancer are preferred. There are two stages to this study: a dose-escalation stage and a dose-expansion stage.

NCT ID: NCT03507543 Recruiting - Breast Cancer Clinical Trials

The Safety and Pharmacokinetics of IMP4297 in Patients With Advanced Solid Tumors

Start date: February 3, 2017
Phase: Phase 1
Study type: Interventional

This is a phase 1, First-In-Human, open label study, trialing a new PARP (poly-ADP ribose polymerase) inhibitor medication IMP4297 in participants with advanced solid tumour.